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This book summarizes the global progress in medical and scientific research toward converting traditionally chronic autoimmune diseases into a drug-free reversible illness using hematopoietic stem cell transplantation (HSCT) and other cellular therapies such as T regulatory cells (Treg), mesenchymal stromal/stem cells, and chimeric antigen receptor T (CAR T) cells in order to reintroduce sustained immune tolerance. This title provides information on different types of stem cells and immune cells; post-transplant immune regeneration; cellular regulatory requirements; ethical and economic considerations; and the advantages and disadvantages of HSCT in the treatment of a variety of autoimmune d...
This open access book provides a concise yet comprehensive overview on how to build a quality management program for hematopoietic stem cell transplantation (HSCT) and cellular therapy. The text reviews all the essential steps and elements necessary for establishing a quality management program and achieving accreditation in HSCT and cellular therapy. Specific areas of focus include document development and implementation, audits and validation, performance measurement, writing a quality management plan, the accreditation process, data management, and maintaining a quality management program. Written by experts in the field, Quality Management and Accreditation in Hematopoietic Stem Cell Transplantation and Cellular Therapy: A Practical Guide is a valuable resource for physicians, healthcare professionals, and laboratory staff involved in the creation and maintenance of a state-of-the-art HSCT and cellular therapy program.
At the outset of the twentieth century, malaria was Italy’s major public health problem. It was the cause of low productivity, poverty, and economic backwardness, while it also stunted literacy, limited political participation, and undermined the army. In this book Frank Snowden recounts how Italy became the world center for the development of malariology as a medical discipline and launched the first national campaign to eradicate the disease. Snowden traces the early advances, the setbacks of world wars and Fascist dictatorship, and the final victory against malaria after World War II. He shows how the medical and teaching professions helped educate people in their own self-defense and in the process expanded trade unionism, women’s consciousness, and civil liberties. He also discusses the antimalarial effort under Mussolini’s regime and reveals the shocking details of the German army’s intentional release of malaria among Italian civilians—the first and only known example of bioterror in twentieth-century Europe. Comprehensive and enlightening, this history offers important lessons for today’s global malaria emergency.
In 2013, Edward Snowden revealed that the NSA and its partners had been engaging in warrantless mass surveillance, using the internet and cellphone data, and driven by fear of terrorism under the sign of ’security’. In this compelling account, surveillance expert David Lyon guides the reader through Snowden’s ongoing disclosures: the technological shifts involved, the steady rise of invisible monitoring of innocent citizens, the collusion of government agencies and for-profit companies and the implications for how we conceive of privacy in a democratic society infused by the lure of big data. Lyon discusses the distinct global reactions to Snowden and shows why some basic issues must be faced: how we frame surveillance, and the place of the human in a digital world. Surveillance after Snowden is crucial reading for anyone interested in politics, technology and society.
NEW YORK TIMES BESTSELLER Edward Snowden, the man who risked everything to expose the US government’s system of mass surveillance, reveals for the first time the story of his life, including how he helped to build that system and what motivated him to try to bring it down. In 2013, twenty-nine-year-old Edward Snowden shocked the world when he broke with the American intelligence establishment and revealed that the United States government was secretly pursuing the means to collect every single phone call, text message, and email. The result would be an unprecedented system of mass surveillance with the ability to pry into the private lives of every person on earth. Six years later, Snowden...
2022 IPPY Silver Medal 2021 Foreword Indies Gold Winner for History 2021-22 Reader Views Literary Awards Silver Medal Winner 2021 Best Book Awards Finalist in US History sponsored by American Book Fest A Second Reckoning tells the story of John Snowden, a Black man accused of the murder of a pregnant white woman in Annapolis, Maryland, in 1917. He refused to confess despite undergoing torture, was tried--through legal shenanigans--by an all-white jury, and was found guilty on circumstantial evidence and sentenced to death. Despite hair-raising, last-minute appeals to spare his life, Snowden was hanged for the crime. But decades after his death, thanks to tireless efforts by interested citize...
It began with an unsigned email: "I am a senior member of the intelligence community". What followed was the most spectacular intelligence breach ever, brought about by one extraordinary man, Edward Snowden. The consequences have shaken the leaders of nations worldwide, from Obama to Cameron, to the presidents of Brazil, France, and Indonesia, and the chancellor of Germany. Edward Snowden, a young computer genius working for America's National Security Agency, blew the whistle on the way this frighteningly powerful organisation uses new technology to spy on the entire planet. The spies call it "mastering the internet". Others call it the death of individual privacy. This is the inside story ...
As seen on "60 Minutes" a "brilliant and sobering" (Paul Kennedy, Wall Street Journal) look at the history and human costs of pandemic outbreaks The World Economic Forum #1 book to read for context on the coronavirus outbreak "Well-written, highly entertaining and relevant."--Financial Times, "Best Books of 2020: Readers' Choice" This sweeping exploration of the impact of epidemic diseases looks at how mass infectious outbreaks have shaped society, from the Black Death to today. In a clear and accessible style, Frank M. Snowden reveals the ways that diseases have not only influenced medical science and public health, but also transformed the arts, religion, intellectual history, and warfare....
A collection of 42 projects in 1/12 scale lace. Advice covers equipment, beginners' braid, stitches and techniques, followed by pieces for every room in the dolls' house. The projects include curtains, shawls, bedspreads, parasols and a tablecloth.