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With its focus on drugs so recently introduced that they have yet to be found in any other textbooks or general references, the information and insight found here makes this a genuinely unique handbook and reference. Following the successful approach of the previous volumes in the series, inventors and primary developers of successful drugs from both industry and academia tell the story of the drug's discovery and describe the sometimes twisted route from the first drug candidate molecule to the final marketed drug. The 11 case studies selected describe recent drugs ranging across many therapeutic fields and provide a representative cross-section of present-day drug developments. Backed by plenty of data and chemical information, the insight and experience of today's top drug creators makes this one of the most useful training manuals that a junior medicinal chemist may hope to find. The International Union of Pure and Applied Chemistry has endorsed and sponsored this project because of its high educational merit.
"Native to the New World, the potato was domesticated by Andean farmers, probably in the Lake Titicaca basin, almost as early as grain crops were cultivated in the Near East. Full of essential vitamins and energy-giving starch, the potato has proved a valuable world resource. Curious Spaniards took the potato back to Europe, from whence it spread worldwide. Today, the largest potato producer is China, with India not far behind. To tell the potato's story, Lang has done fieldwork in South America, Asia, and Africa."--Jacket.
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The honey bees were formerly seen as a small, static group comprising four species, whose behavior and ecology were simple variants on the patterns found in Apis mellifera. The picture now is one of a large, actively speciating group, reflecting in part the complex geological and biological influence of the Apis environment. Research on this diversity has benefitted from new techniques of DNA analysis applied to several long-standing problems in honey bee phylogenetics and that are reported in this volume. The behavior and ecology of the Apis species and populations are also more diverse and differentiated than previously recognized: Radically different orientation systems as expressed through dance language exist in various species. This study of Apis will be of great interest not only to biologists and apiculturalists but to anyone interested in systematics, genetics, and ethology. Our view of apis has changed radically in the past few years as a result of recent research on the Asian honeybee. The contributors to this book focus on systematics, genetics, behaviour and ecology to offer a synthesis for understanding this economically and scientifically important genus.