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NEW YORK TIMES BESTSELLER • “An impassioned book, laced with anger and indignation, about how our public education system scorns so many of our children.”—The New York Times Book Review In 1988, Jonathan Kozol set off to spend time with children in the American public education system. For two years, he visited schools in neighborhoods across the country, from Illinois to Washington, D.C., and from New York to San Antonio. He spoke with teachers, principals, superintendents, and, most important, children. What he found was devastating. Not only were schools for rich and poor blatantly unequal, the gulf between the two extremes was widening—and it has widened since. The urban school...
The advent of next-generation sequencing technologies has resulted in a remarkable increase our understanding of human and animal neurological disorders through the identification of disease causing or protective sequence variants. However, in many cases, robust disease models are required to understand how changes at the DNA, RNA or protein level affect neuronal and synaptic function, or key signalling pathways. In turn, these models may enable understanding of key disease processes and the identification of new targets for the medicines of the future. This e-book contains original research papers and reviews that highlight either the impact of next-generation sequencing in the understanding of neurological disorders, or utilise molecular, cellular, and whole-organism models to validate disease-causing or protective sequence variants.
Amazing Grace is Jonathan Kozol’s classic book on life and death in the South Bronx—the poorest urban neighborhood of the United States. He brings us into overcrowded schools, dysfunctional hospitals, and rat-infested homes where families have been ravaged by depression and anxiety, drug-related violence, and the spread of AIDS. But he also introduces us to devoted and unselfish teachers, dedicated ministers, and—at the heart and center of the book—courageous and delightful children. The children we come to meet through the friendships they have formed with Jonathan defy the stereotypes of urban youth too frequently presented by the media. Tender, generous, and often religiously devout, they speak with eloquence and honesty about the poverty and racial isolation that have wounded but not hardened them. Amidst all of the despair, it is the very young whose luminous capacity for love and transcendent sense of faith in human decency give reason for hope.
Comprehensive and complete, Shackelford’s Surgery of the Alimentary Tract delivers the definitive, clinically oriented, cutting-edge guidance you need to achieve optimal outcomes managing the entire spectrum of gastrointestinal disorders. Make effective use of the latest endoscopic, robotic, and minimally invasive procedures as well as medical therapies with unbeatable advice from a "who’s who" of international authorities! Find expert answers to any clinical question in gastrointestinal surgery, from the esophagus to the colon. See exactly what to look for and how to proceed from an abundance of beautifully detailed intraoperative and laparoscopic photographs.
"Extraordinarily affecting....A very important book....To read and remember the stories in this book, to take them to heart, is to be called as a witness." THE BOSTON GLOBE There is no safety net for the millions of heartbroken refugees from the American Dream, scattered helplessly in any city you can name. RACHEL AND HER CHILDREN is an unforgettable record for humanity, of the desperate voices of the men, women, and especially children, and their hourly struggle for survival, homeless in America.
Since the early 1980s, when the federal courts began dismantling the landmark ruling in Brown v. Board of Education, segregation of black children has reverted to its highest level since 1968. In many inner-city schools, a stick-and-carrot method of behavioral control traditionally used in prisons is now used with students. Meanwhile, as high-stakes testing takes on pathological and punitive dimensions, liberal education has been increasingly replaced by culturally barren and robotic methods of instruction that would be rejected out of hand by schools that serve the mainstream of society. Filled with the passionate voices of children, principals, and teachers, and some of the most revered leaders in the black community, The Shame of the Nation pays tribute to those undefeated educators who persist against the odds, but directly challenges the chilling practices now being forced upon our urban systems. In their place, Kozol offers a humane, dramatic challenge to our nation to fulfill at last the promise made some 50 years ago to all our youngest citizens.
First multi-year cumulation covers six years: 1965-70.