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At the time of the first edition of Principles of Cancer Biotherapy in 1987, this book represented the first comprehensive textbook on biological therapy. In 1991, when the second edition was published, there was still some doubt on the part of many oncologists and cancer researchers as to the therapeutic value of these new approaches. By 2003 and the fourth edition, it was generally agreed that biopharmaceuticals were producing major opportunities for new cancer therapies. Cancer biotherapy has now truly matured into the fourth modality of cancer treatment. This fifth revised edition describes the tremendous progress that has been made in recent years using biologicals in cancer treatment. ...
The book summarizes an evolving science and a rapidly changing medical practice. In this new millennium, it now becomes possible to envision a much more diversified system of cancer research and treatment that will afford greater opportunities for patients. Some forms of cancer biotherapy use the strategy of tumour stabilization and control through continued biological therapy, akin to the use of insulin in the treatment of diabetes. This textbook illustrates new methods of thinking and new strategies for control of cancer. It is always difficult to move from past dogma to future opportunity, but this fourth edition of Principles of Cancer Biotherapy illustrates why it is so important to the patients, for researchers and clinicians to explore and apply these new opportunities in cancer biotherapy.
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A Neurosurgeon discovers the chemical basis connecting life and death, and now the mob and FDA are out to steal his discovery and destroy him.
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Biological Response Modifiers: New Approaches to Disease Intervention focuses on biological response modifiers (BRMs) and the ways they provide novel approaches to disease control. It examines how BRMs act through an organism's own biological response mechanisms and how their mechanisms of action can be utilized to develop new modalities of chemotherapy. Organized into 15 chapters, this volume begins with an overview of specific agents and approaches to biological therapy, the basic concepts of immunity, and BRM screening. It then discusses interferons and their immunoregulatory functions; mechanism of interferon action; how nucleic acids and polynucleotides regulate the immune system; clini...