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Epigenetics
Epigenetic changes are heritable and reversible modifications that significantly affect gene expression without any change in DNA sequence. The epigenetic signature is remodelled during the lifespan as a direct consequence of both environment and lifestyle. Therefore, health or disease status strongly depends on epigenetic marks. This book summarizes the current knowledge in the field and includes chapters on epigenetics in plants and epigenetics in health and disease. It is written for a wide audience of basic and clinical scientists, teachers and students interested in gaining a better understanding of epigenetics.
Spermatozoa
Spermatozoa, the haploid male gametes, are highly specialized cells capable to fertilize eggs in order to produce diploid zygote. The biogenesis of spermatozoa requires finely modulated occurrence of mitotic, meiotic, and differentiation events. Hence, the production of high-quality spermatozoa impacts fertilization with outcomes on the health of the offspring. This book provides a comprehensive overview on the biogenesis, maturation, functions and activities of spermatozoa in both physiological conditions and infertility. Particular attention has been addressed to the impact of environment on sperm quality and to the appropriate selection of high-quality spermatozoa for in vitro fertilization. Taken together, this book targets a wide audience of basic and clinical scientists, teachers and students, and offers a better understanding of spermatozoa health and disease.
Modulators of hypothalamic-pituitary-gonadal axis for the control of spermatogenesis and sperm quality in vertebrates
Spermatogenesis is a process highly conserved throughout vertebrate species and is mainly under hypothalamic-pituitary control. It occurs in the testis in a stepwise fashion so that committed spermatogonia develop into spermatocytes and enter meiosis to produce round spermatids. These undergo a morphological transformation (spermiogenesis) into mature spermatids (i.e.: spermatozoa), which are differentially released from Sertoli cells (spermiation) depending on the species. In mammals, further transformations are necessary to form mature spermatozoa, suitable for fertilization. Gonadotropins, mainly responsive to gonadotropin-releasing hormone, control spermatogenesis through specific recept...
Cannabinoids in Health and Disease
This book provides a comprehensive overview of current knowledge of cannabinoid activity in human physiology and points out the importance of endocannabinoid system for the maintenance of human health and treatment of diseases. Each chapter has been organized with the aim to cover basic concepts in the modulation of endocannabinoid system in both physiological and pathological conditions, thanks to the integration of data from experimental animal models and clinical observations. A special focus has been put on the medical use of cannabinoids and on the targeting of endocannabinoid system as new therapeutic strategy for the prevention and treatment of human diseases. Taken together, this book targets a wide audience of basic and clinical scientists, teachers and students interested in gaining a better understanding in the field of cannabinoids.
The Multiple Facets of Kisspeptin Activity in Biological Systems
In 1996 a cDNA called KISS1 (KI in reference to the place of discovery-Hershey Pennsylvania, home of the famous Hershey Chocolate Kisses- and SS as suppressor sequence) was identified in non-metastatic melanoma cell lines. Its 54 amino-acid product, Kisspeptin-54 (Kp-54), was originally called metastin for its ability to inhibit cancer metastasis through the activation of a G coupled receptor, previously known as GPR54 and currently renamed the Kisspeptin receptor (KISS1R). Shorter active peptides all capable of binding to KISS1R have been identified and the physiological activities of these Kisspeptins are now known to extend not only to the suppression of metastasis. Kisspeptins currently ...
Stars and Rising Stars in Neuroendocrinology
Recognizing the future leaders of Neuroendocrine Science is fundamental to safeguarding tomorrow's driving force in innovation. This collection will showcase the high-quality work of internationally recognized researchers both in the midst and in the early stages of their careers. We aim to highlight research by leading scientists of the future across the entire breadth of neuroendocrinology, and present advances in theory, experiment and methodology with applications to compelling problems. Please note, contributions to the collection are by invitation only. Please inform the Editorial Office at endocrinology.editorial.office@frontiersin.org once you are prepared to submit. This Research Topic will accept the following article types: Original Research; Review; Mini Review; Systematic Review; Methods; Hypothesis and Theory; Opinion; and Perspective. All Rising Star researchers will be suggested by established Editors in recognition of their influence on the future directions in their respective fields.
International Review of Cytology
International Review of Cytology presents current advances and comprehensive reviews in cell biology—both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. - Authored by some of the foremost scientists in the field - Provides up-to-date information and directions for future research - Valuable reference material for advanced undergraduates, graduate students and professional scientists
Hormones and Reproduction of Vertebrates, Volume 2
Hormones and Reproduction of Vertebrates, Volume 2: Amphibians is the second of five second-edition volumes representing a comprehensive and integrated overview of hormones and reproduction in fishes, amphibians, reptiles, birds, and mammals. The book includes coverage of endocrinology, neuroendocrinology, physiology, behavior, and anatomy of amphibian reproduction. It provides a broad treatment of the roles of pituitary, thyroid, adrenal, and gonadal hormones in all aspects of reproduction, as well as descriptions of major life history events. New to this edition is a concluding assessment of the effect of environmental influences on amphibians. Initial chapters in this book broadly examine...
Science and Engineering of Polyphenols
SCIENCE AND ENGINEERING OF POLYPHENOLS A groundbreaking synthesis of rich and varied polyphenol research Polyphenols are a class of compounds, found naturally in fruits and vegetables, whose flexibility and ubiquity give them a vast range of applications in pharmaceutical, environmental, and biological research and development. They play a role in diagnosing and preventing diseases from diabetes to Parkinson’s to Alzheimer’s and have been integral in food preservation. The field of polyphenols research has the potential to touch virtually every area of organic production. Science and Engineering of Polyphenols provides a current and comprehensive overview of this field of research and it...
Anandamide
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume reviews recent advances in the formation of endogenous cannabinoids and their receptors, metabolism and relation to disease processes. - Longest running series published by Academic Press - Contributions by leading international authorities
