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Bacterial and Eukaryotic Porins
This first book dedicated to the topic relates the known physiological functions of porins to their molecular structure and mechanism, as documented by various in vitro and in vivo methods, including the generation of null mutants in mice. For the first time, it brings together biophysical evidence with studies performed in a cellular context, presenting a unified picture of the fundamental importance of porins for cellular function. With 16 contributions by an interdisciplinary team of leading porin researchers, this reference is essential reading for every molecular or structural biologist with an interest in this essential protein family.
The Handbook of Mass Media Ethics
This Handbook encapsulates the intellectual history of mass media ethics over the past twenty-five years. Chapters serve as a summary of existing research and thinking in the field, as well as setting agenda items for future research. Key features include: up-to-date and comprehensive coverage of media ethics, one of the hottest topics in the media community 'one-stop shopping' for historical and current research in media ethics experienced, top-tier editors, advisory board, and contributors. It will be an essential reference on media ethics theory and research for scholars, graduate students, and researchers in media, mass communication, and journalism.
Growing Up Fast
The first edition of Growing Up Fast attempted to counter the stereotype of poor, minority adolescent mothers and describe the diversity of their educational, work, parenting, and relationship experiences. The volume followed a strengths-based approach to understanding why some mothers appeared resilient to the stresses of early parenting, compared to their peers, and what obstacles undermine resiliency for some of these young women. We hear their stories in their own words. We also see how many disadvantaged mothers go on to succeed in school, work, and parenting while avoiding many of the risk associated with teen parenting . The research is based on a six-year study of 120 young disadvant...
100 Years On: Revisiting the First Russian Art Exhibition of 1922
The First Russian Art Exhibition (Erste Russische Kunstausstellung), which opened at the Galerie van Diemen in Berlin on October 15, 1922, and later travelled to Amsterdam, introduced a broad Western audience to the most recent artistic developments in Russia. The extensive show – more than a thousand works, including paintings, graphic works, sculptures, stage designs, architectural models, and works of porcelain – was remarkably inclusive in its scope, which ranged from traditional figurative painting to the latest constructions of the Russian avant-garde. Coming on the heels of the Treaty of Rapallo, the exhibition was a first cultural step towards bilateral relations between two youn...
Visual Pedagogies
This international collection presents theoretical, empirical and practice-led considerations of what can be envisioned as visual pedagogies, offering classic, creative, and contemporary re-workings of these paradigms. In complementary yet overlapping parts, this book explores understandings of visual pedagogies as learning with, through and/or about images, visual and digital environments, embodied performances and immersive experiences. As visual practices in academia gain momentum, the need to navigate visuality in ways that enhance sensibility and awareness of how/what we observe, analyze, criticize and reflect on in any given moment continues to grow. We understand visual pedagogies as ...
Cancer Associated Viruses
The acknowledgment that viruses are potent biological factors in driving many cancers have seen a dramatic upsurge in recent years in large part to the success of the human papilloma virus vaccine against invasive cervical carcinomas and followed by the awarding of the noble prize in medicine in 2008 to Dr. Harald zurHausen who identified the link between papilloma virus and cervical cancers. Over the last few years there have been some volumes addressing different aspects of viruses and cancers and to some extent focusing on the DNA viruses, more specifically the human DNA viruses. This proposed volume will attempt to review and address the major gaps in current knowledge in DNA viruses as well as RNA viruses bringing a historical perspective of where studies began to a more recent molecular approach and vaccine successes in tumor viruses. We will also cover other known oncogenic viruses associated cancers in other mammals in addition to humans.
PI3K signalling
The PI3Ks control many key functions in immune cells. PI3Ks phosphorylate PtdIns(4,5)P2 to yield PtdIns(3,4,5)P3. Initially, PI3K inhibitors such as Wortmannin, LY294002 and Rapamycin were used to establish a central role for Pi3K pathway in immune cells. Considerable progress in understanding the role of this pathway in cells of the immune system has been made in recent years, starting with analysis of various PI3K and Pten knockout mice and subsequently mTOR and Foxo knockout mice. Together, these experiments have revealed how PI3Ks control B cell and T cell development, T helper cell differentiation, regulatory T cell development and function, B cell and T cell trafficking, immunoglobulin class switching and much, much more. The PI3Kd inhibitor idelalisib has recently been approved for the treatment of B cell lymphoma. Clinical trials of other PI3K inhibitors in autoimmune and inflammatory diseases are also in progress. This is an opportune time to consider a Research Topic considering when what we have learned about the PI3K signalling module in lymphocyte biology and how this is making an impact on clinical immunology and haematology.
Periodontitis
Periodontitis is a disease that affects more than half the adult population in the world. Treatment is often based on ancient recommendations consisting in mechanically removing material from damaged zones. However, novel therapeutic management strategies exist, from prevention to efficient treatment, and regeneration. The need of integrative approaches to circumvent this worldwide pledge can be achieved through: A better understanding of this complex disease by promoting scientific research and a comprehensive multidisciplinary approach, including epidemiology, microbiology, immunology, physiology, therapeutics, psychology, etc. A better outreach by promoting vulgarization and recommendatio...
