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Haplotyping
This book aims to be an introduction to haplotype information for both the wet and dry labs. Chapters detail co-barcoding and linked-reads based methods, third generation sequencing based methods, Hi-C based methods, single-cell and Strand-seq, and methods for using haplotype data once obtained. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Haplotyping: Methods and Protocols aims to provide compréhensive and accessible methods to undergraduate, graduate, and established scientists.
Optical and Optoelectronic Polymers
The field of optoelectronic polymers has continuously expanded in the past two decades because of their innovative applications in a variety of technologies in optoelectronic, photonic and energy research. Groups across the world are still looking into the fundamentals, as well as their applications, which remain to be fully understood and envisioned. This is the first book on the topic for researchers who are entering the field, highlighting the remarkable basic science and technological potential of this class of materials. Chapters will focus on the fundamental concepts as well as up-and-coming research into the applications of these polymers. Chapters will look at topics such as pure organic phosphorescence and external stimuli-responsive luminescent materials that are not covered in other books.
Synthetic Biology
Leading researchers draw on the recent literature in Synthetic Biology, from both dedicated journals and broader sources, making this an essential reference to any library supporting this research in this emerging field.
Love, Sex, and Marriage
If the language we use influences and reflects the way that we see the world, then the fields of LOVE, SEX, and MARRIAGE, will show how speakers of English view their closest social and emotional relationships. Love, Sex, and Marriage provides a classification of English terms for these three fields from the earliest written records of the language until the present day. This volume makes it possible to trace changing attitudes towards social and sexual ties, and to understand those ties as earlier speakers of English did, through the language they used. The terms are arranged by meaning, and are listed chronologically within semantic fields, with their dates of usage. Notes on individual terms provide further information about their connotations and development. Language does not exist in isolation from the people who speak it, so background information about changes in social conditions, religious beliefs, and medical advancements is also included. A brief introduction to basic semantic terminology explains the principles behind the classification, and an alphabetical index facilitates the location of individual terms.
Telephone Directory
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Transcriptomics in Health and Disease
The study of transcriptomics is key to understanding complex diseases. This new edition will build on the foundation of the first edition while incorporating the progress that has been made in the field of transcriptomics in the past six years, including bioinformatics for data analysis. Written by leading experts, chapters address new subjects such as methodological advances in large-scale sequencing, the sequencing of single-cells, and spatial transcriptomics. The new edition will address how transcriptomics may be used in combination with genetic strategies to identify causative genes in monogenic and complex genetic diseases. Coverage will also explore transcriptomics in challenging groups of diseases, such as cancer, inflammation, bacterial infection, and autoimmune diseases. The updated volume will be useful for geneticists, genome biologists, biomedical researchers, molecular biologists, bioinformaticians, and students, among others.
RNA and Cancer
Accumulating evidence supports the role of defects in post-transcriptional gene regulation in the development of cancer. RNA and Cancer examines the recent advances in our understanding of post-transcriptional gene regulation, especially RNA processing and its role in cancer development and treatment. A particular focus is mRNA splicing, but other topics such as microRNAs, mRNA stability, the perinucleolar compartment, and oligonucleotide therapeutics are also covered in detail. All chapters have been written by internationally renowned experts. The book is intended for all with an interest in gene regulation and cancer biology, and especially for those not directly working on RNA biology, including clinicians and medical students. It is hoped that it will stimulate further innovative research collaborations between RNA biologists and cancer researchers to the benefit of patients.
Advances in Vascular Medicine
Understanding the many complex cellular and molecular mechanisms underlying human vascular diseases is essential in improving the treatment of this important and wide-ranging group of diseases that affect a large proportion of the world po- lation. This book is based on lectures presented at an International Vascular Biology Workshop held in London and chaired by Professor Dame Carol Black. The c- tents are complemented by some invited chapters, all written by world experts in areas of basic science and clinical medicine highly relevant to vascular biology and disease. We are particularly grateful to Professor Arshed Quyyumi, Professor of Medicine and Cardiology at Emory University, who with...
Making Scientists
For many college students, studying the hard sciences seems out of the question. Students and professors alike collude in the prejudice that physics and molecular biology, mathematics and engineering are elite disciplines restricted to a small number with innate talent. Gregory Light and Marina Micari reject this bias, arguing, based on their own transformative experiences, that environment is just as critical to academic success in the sciences as individual ability. Making Scientists lays the groundwork for a new paradigm of how scientific subjects can be taught at the college level, and how we can better cultivate scientists, engineers, and other STEM professionals. The authors invite us ...
Urological Oncology
As a professional resource for all doctors, oncologists and urologists involved in the care of uro-oncology patients, this book puts emphasis on developing advanced practice with in-depth discussions to support evidence based, patient focused care. Urological Oncology, Second Edition offers an updated multi-disciplinary and multi professional approach to the assessment, diagnosis, treatment and follow-up care of patients being investigated and treated for urological malignancies. Mainly aimed at oncologists and urologists, it is also useful for general physicians as well as trainee nurses and nurse practitioners in urology / urological oncology.
