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The gastrointestinal tract has a number of unique features. Its extensive surface is formed by a single layer of rapidly renewing cells, the intestinal epithelial cells. These cells are in contact with a number of other cell populations, including the largest part of the immune system, and with an excessive luminal antigen load, including vast numbers of bacteria. Furthermore two more organs, namely liver and pancreas, are part of the system. The rapid renewal of the epithelial layer, the interactions of different cell types, and the balance between cell proliferation and death, have been fascinating subjects of studies in recent years. Much has been learned, and cytokines have emerged as important mediators for all these interactions and homeostatic systems. This book, the proceedings of the Falk Symposium 113 on `Cytokines and Cell Homeostasis in the Gastrointestinal Tract', held in Regensburg, Germany, 16-18 September 1999, provides a forum for basic scientists and interested clinicians to exchange ideas, to discuss concepts and to plan further studies.
Physiology of the Gastrointestinal Tract, Fifth Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine — covers the study of the mechanical, physical, and biochemical functions of the GI Tract while linking the clinical disease or disorder, bridging the gap between clinical and laboratory medicine. The gastrointestinal system is responsible for the breakdown and absorption of various foods and liquids needed to sustain life. Other diseases and disorders treated by clinicians in this area include: food allergies, constipation, chronic liver disease and cirrhosis, gallstones, gastritis, GERD, hemorrhoids, IBS, lactose intolerance, pancreatic, appendicitis,...
This book addresses three fundamental building blocks of JIT, namely setting up a JIT production system, improving quality, and instilling total employee involvement. JIT implementation issues are covered and supported by an industrial case study.
"Exorbitant prices for lifesaving drugs, safety recalls affecting tens of millions of Americans, and soaring rates of addiction and overdose on prescription opioids have caused many to lose faith in pharmaceutical companies. Now, Americans are demanding national reckoning with a monolithic industry. In Pharma, award-winning journalist and New York Times best-selling author Gerald Posner uncovers the real story of the Sacklers, the family that became one of America's wealthiest from the success of OxyContin, their blockbuster narcotic painkiller at the centure of the opioid crisis. The unexpected twists and turns of the Sakler family saga are told against the startling chronicle of a powerful industry that sits at the intersection of public health and profits. Pharma reveals how and why American drug companies have put earnings ahead of patients"--
A new method for making phenological forecasts and bioclimatic estimations; Theory and characteristics of phenotemperature nomograms (PTNs); a brief description of forecasting the yield, and numbers of parasites; Phytophenological forecasts and bioclimatic estimations; Phenologicalo forecasts and bioclimatic estimations for entonologists and phytopathologists; Combined phenological forecasting as a method for the study and management of agroecosystems (agrobiogeocenoses); The new ex perimental-mathematical method for phenological forecasting and bioclimatic estimations in medical and veterinary parasitology and virology; Application of the phenological method in microbiology, forecasting the ducation of the bactericidal phase of milk. Forescasting the durationof butter formation in cream; The general phenological principle; Criticism against the podolsky method, and the dissemination of this mew method; Further development of the theory and practice of the podolski method, and its prospects.
First comprehensive collection of Feyerabend's philosophy of quantum physics, the hotbed of all key issues of his most debated ideas.
Information theory is essentially about correlations, and the novel approach of Bananaworld is to get at what's counterintuitive about quantum information by considering correlations between normally mundane experiences that every reader can relate to.
Written in clear, straightforward language, Just-in-Time Manufacturing: An introduction discusses in-depth the implementation of JIT manufacturing. The objectives are twofold: firstly, to acquaint the reader with the overall JIT concept and the factors necessary for its implementation, and secondly to reinforce this with an actual case study of JIT implementation in a manufacturing company.
Human health issues relating to amino acids are extremely broad and include metabolic disorders of amino acid metabolism as well as their presence in food and use as supplements. This book covers the biochemistry of amino acid metabolism in the context of health and disease. It discusses their use as food supplements, in clinical therapy and nutritional support and focuses on major recent developments, highlighting new areas of research that will be needed to sustain further interest in the field.