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Experimental and Computational Methods in the Development of Diagnostics and Therapeutics for Colon Cancer
Cancer continues to be one of the major causes of illness and death worldwide. Cancer is growing at a shocking speed and touches every geographic region of the world. It is predicted that by 2030 there will be 21.7 million new cases and 13 million deaths. To overcome this problem efficiently and to make significant progress in cancer research and therapy, both the scientific and healthcare sectors must work together. Recent advancements in the development of AI-based methods i.e. ensemble or stacking algorithms to discover novel biomarkers using gene expression and other data provide greater opportunity for complete data analysis to decipher the mechanism of colon cancer initiation, progress...
Emerging Optical Network Technologies
Optical networks have moved from laboratory settings and theoretical research to real-world deployment and service-oriented explorations. New technologies such as Ethernet PON, traffic grooming, regional and metropolitan network architectures and optical packet switching are being explored, and the landscape is continuously and rapidly evolving. Some of the important issues involving these new technologies involve the architectural, protocol, and performance related issues. This book addresses many of these issues and presents a birds eye view of some of the more promising technologies. Researchers and those pursuing advanced degrees in this field will be able to see where progress is being made and new technologies are emerging. Emerging Optical Network Technologies: Architectures, Protocols and Performance provides state-of-the-art material written by the most prominent professionals in their respective areas.
Focus on Leukemia Research
This new book brings together leading research from around the globe. Leukaemia is cancer that begins in blood cells. In people with leukaemia, the bone marrow produces abnormal white blood cells. The abnormal cells are leukaemia cells. At first, leukaemia cells function almost normally. In time, they may crowd out normal white blood cells, red blood cells, and platelets. The scope of the book includes the four common types of leukaemia: chronic lymphocytic leukaemia (chronic lymphoblastic leukaemia, CLL) - most often affecting people over age 55; chronic myeloid leukaemia (chronic myelogenous leukaemia, CML) - affects mainly adults; acute lymphocytic leukaemia (acute lymphoblastic leukaemia, ALL) - the most common type of leukaemia in young children; and acute myeloid leukaemia (acute myelogenous leukaemia, AML) - which occurs in both adults and children. New advances in diagnosis, pathogenesis and therapy are also presented.
Transcription Factors
Transcription Factors Normal and Malignant Development of Blood Cells Katya Ravid and Jonathan Licht The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearranged and aberrantly activated in leukemias (blood malignancies). Transcription Factors: Normal and Malignant Development of Blood Cells focuses on those major transcription factors involved in activation of lineage-specific gene expression during normal versus malignant development of specific blood lineages, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification...
Photochemistry
This annual review, the 50th volume in the series, provides critical analysis for anyone wanting to keep up to date with the literature on photochemistry and its applications. This essential volume combines reviews on the latest advances in photochemical research with specific topical highlights in the field. The volume starts with periodical reports of the recent literature on organic and computational aspects, including computational advances in photochemistry, chemiluminescence and dark photochemistry, organic aspects of photochemistry of alkenes, dienes and polyenes, aromatic compounds, oxygen-containing functions and those functions containing other heteroatoms, and finally a chapter on...
Targeted Genome Engineering via CRISPR/Cas9 in Plants
Targeted Genome Engineering via CRISPR/Cas9 in Plants provides in-depth insights into the use of the emerging "CRISPR/Cas9" technology for precise genome editing. This technology has revolutionized plant science research particularly for crop improvement owing to its simplicity and efficiency. The book provides a wide range of CRISPR/Cas9 gene editing techniques for a variety of plants. Chapters include the latest applications of CRISPR/Cas9 system in connection with abiotic stresses, biotic stresses, biofortification, yield improvement, disease modelling and prognosis and molecular diagnosis. Targeted Genome Engineering via CRISPR/Cas9 in Plants also evaluates various regulatory and ethical...
Cholera and the Ecology of Vibrio cholerae
Only in recent years has it been revealed that V. cholerae is a normal inhabitant of esturine and riverine waters. This means that even if the disease can be eliminated from human population by vaccines etc. the vibrio will continue to survive independently in the environment. It is likely that the environment is the source of epidemic strains. This is the first book to focus on the implication of these discoveries.
