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Other People's Houses
'First published 54 years ago and yet feels as timely as any book I've read this year' Observer Nine months after the Nazi occupation of Austria, 600 Jewish Children assembled at Vienna station to board the first of the Kindertransports bound for Britain. Among them was 10 year old Lore Segal. For the next seven years, she lived as a refugee in other people's houses, moving from the Orthodox Levines in Liverpool, to the staunchly working class Hoopers in Kent, to the genteel Miss Douglas and her sister in Guildford. Few understood the terrors she had fled, or the crushing responsibility of trying to help her parents gain a visa. Amazingly she succeeds and two years later her parents arrive; their visa allows them to work as domestic servants - a humiliation for which they must be grateful. In Other People's Houses Segal evokes with deep compassion, clarity and calm the experience of a child uprooted from a loving home to become stranded among strangers.
Biochemistry and Molecular Genetics of Cancer Metastasis
The success rate for treatment of primary neoplasms has improved sig nificantly due to improved surgical, radiotherapy, and chemotherapy methods, and by supportive patient care. In contrast, the treatment of cancer metastases, the cause of most cancer deaths, has not been very successful. Approximately 50% or more of patients with primary malignant neoplasms already have established metastases. Consequently, the most important problem in cancer treatment is the destruction or prevention of metastases. Metastases research has obvious clinical importance. Yet it has only been recently that investigators have attempted to study the mechanisms in volved in this process. This is in part due to th...
New Experimental Modalities in the Control of Neoplasia
Acquisition of new knowledge about the biological and bio chemical nature of neoplastic cells has led to the design and development of several experimental approaches in the tre&tment of cancer. These approaches emerge from the recent work in tu mor virology, e. g. the control of vital cellular genes by viral regulatory signals; the implication of monoclonal antibodies as a vehicle for the targeted drug delivery and selective de struction of tumor cells; immunologic advances in the recog nition of some specific events during metastatic growth; the role of biological response modifiers in modifying or rever sing malignant growth; and biochemical advances, such as the role of gene amplificatio...
Shakespeare's Kitchen
The thirteen interrelated stories of Shakespeare's Kitchen concern the universal longing for friendship, how we achieve new intimacies for ourselves, and how slowly, inexplicably, we lose them. Featuring six never-before-published pieces, Lore Segal's stunning new book evolved from seven short stories that originally appeared in the New Yorker (including the O. Henry Prize–;winning “The Reverse Bug”). Ilka Weisz has accepted a teaching position at the Concordance Institute, a think tank in Connecticut, reluctantly leaving her New York circle of friends. After the comedy of her struggle to meet new people, Ilka comes to embrace, and be embraced by, a new set of acquaintances, including the institute's director, Leslie Shakespeare, and his wife, Eliza. Through a series of memorable dinner parties, picnics, and Sunday brunches, Segal evokes the subtle drama and humor of the outsider's loneliness, the comfort and charm of familiar companionship, the bliss of being in love, and the strangeness of our behavior in the face of other people's deaths. A magnificent and deeply moving work, Shakespeare's Kitchen marks the long-awaited return of a writer at the height of her powers.
Her First American
Hailed by the New York Times as coming “closer than anyone to writing The Great American Novel,” Lore Segal stuns with this passionate love story of a refugee from Hitler’s Europe and a witty, hard-drinking black intellectual For Ilka Weissnix, everything is new. Having recently arrived in the United States, she is determined to escape the immigrant communities of New York and boards a train headed west to discover “the real America.” She finds Carter Bayoux “sitting on a stool in a bar in the desert, across from the railroad.” Older, portly, experienced, and black, Carter is magnetic. To Ilka, he exemplifies the values and cultures of a changing America. In order to understand...
Physiology of Membrane Disorders
The second edition of Physiology of Membrane Disorders represents an extensive revision and a considerable expansion of the first edition . Yet the purpose ofthe second edition is identical to that of its predecessor, namely, to provide a rational analysis of membrane transport processes in individual membranes, cells, tissues, and organs, which in tum serves as a frame of reference for rationalizing disorders in which derangements of membrane transport processes playa cardinal role in the clinical expression of disease. As in the first edition, this book is divided into a number of individual, but closely related, sections. Part V represents a new section where the problem of transport acro...
Clinical Disorders of Membrane Transport Processes
Clinical Disorders of Membrane Transport Processes is a softcover book containing a portion of Physiology of Membrane Disorders (Second Edition). The parent volume contains six major sections that deal with general aspects of the physiology of transport processes and specific aspects of transport processes in cells and in organized cellular systems, namely epithelia. This text contains the last section, which deals with the application of the physiology of transport processes to the understanding of clinical disorders. We hope that this smaller volume will be helpful to individuals particularly interested in clinical derangements of membrane transport processes. THOMAS E. ANDREOLI JOSEPH F. ...
Advances in Cancer Research
ADVANCES IN CANCER RESEARCH is a biannual publication that includes timely reviews on the most cutting-edge issues in cancer research. Volume 66 contains encompassing overviews of p53 and its role in both breast cancer and in the cell cycle. Approximately 50% of all human tumors involve mutations of the p53 gene, suggesting that proper understanding of its properties and mechanisms could offer real hope for finding successful clinical therapy. Other themes presented in Volume 66 include cyclins and cyclin-dependent kinases in the cell cycle. Approximately 50% of all human tumors involve mutations of the p53 gene, suggesting that proper understanding of its properties and mechanisms could off...
