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Wonder Drug
  • Language: en
  • Pages: 449

Wonder Drug

  • Type: Book
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  • Published: 2024-07-23
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  • Publisher: Random House

“A shocking saga of pharmaceutical malpractice . . . Wonder Drug is both a first-rate medical thriller and the searing account of a forgotten American tragedy.”—Patrick Radden Keefe, author of Empire of Pain A “fascinating and compassionate” (People) account of the most notorious drug of the twentieth century and the never-before-told story of its American survivors. Longlisted for the Andrew Carnegie Medal In 1959, a Cincinnati pharmaceutical firm, the William S. Merrell Company, quietly began distributing samples of an exciting new wonder drug already popular around the world. Touted as a sedative without risks, thalidomide was handed out freely, under the guise of clinical trial...

Metal Ions in Neurological Systems
  • Language: en
  • Pages: 247

Metal Ions in Neurological Systems

Metal ions in the brain are a necessity as well as a poison. The presence of metal ions in the active sites of biological catalysts or metalloproteins and in the biological functioning of nucleic acids is very well documented and they are required for brain activity. On the other hand, metals are very effective in generating oxidative stress. This effect does not only play a role in immunology but also is the root of practically all neurodegenerative disorders by inducing disease via the death of neurons. Managing metal ions in the brain could therefore be an important strategy in the search for therapeutic agents used in the treatment of neurodegenerative diseases. This new title gives an overview to key topics in the area of metal ions in the brain. It focuses on the role of metal ions in neurological systems by describing their advantageous functions as well as their poisonous features. It is therefore of interest for scientists in biochemistry and biophysics, physiology, toxicology as well as for physicians focused on this topic.

Aesthetics and Politics in Modern German Culture
  • Language: en
  • Pages: 298

Aesthetics and Politics in Modern German Culture

  • Categories: Art
  • Type: Book
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  • Published: 2010
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  • Publisher: Peter Lang

"The papers... were delivered at a conference, Aesthetics and Politics in Modern German Culture, which was held in honour of Professor Rhys W. Williams ... the conference took place, from 31 August to 2 September 2008, at the University of Wales Conference Centre, Gregynog Hall" --Foreword.

Surf Dog Miracles
  • Language: en
  • Pages: 36

Surf Dog Miracles

One morning in September 2011, a large crowd gathered at the shore in Huntington Beach, California. The people had come to watch dozens of surfers ride the rolling ocean waves. This wasn’t just any surfing competition, however—the surfers were dogs! With more than a thousand fans cheering the competitors on, an English bulldog named Sir Hollywood rode a long wave and was declared one of the winners. Surf dog competitions are fairly new, but dogs have been riding surfboards with their owners for fun since the 1920s. In Surf Dog Miracles, kids will meet the talented dogs that learn to balance on a surfboard, recover if they almost fall off the board, and even surf backward. Some surf dogs raise money for charity, while others can help people with disabilities ride a wave. Packed with real-life stories and full-color photos of these special animals, this book is sure to be a favorite of dog lovers everywhere.

The Waiting Water
  • Language: en
  • Pages: 150

The Waiting Water

The Waiting Water addresses one of the most recurrent and troubling motifs in German Realist literature—death by drowning. Characters find themselves before bodies of water, presented with the familiar realm above the surface and the unobservable, uncanny domain beneath it. With somber regularity, they then disappear into the depths. Alexander Sorenson explores the role that these hidden deaths in water play within a literary movement that set out precisely to reveal universal truths about human life. The poetics of submergence, he argues, revolve around two concepts fundamental to Poetic Realism—order and sacrifice. Focusing on texts by Adalbert Stifter, Gottfried Keller, Marie von Ebner-Eschenbach, and Theodor Storm, along with material from earlier and later epochs, The Waiting Water shows that the pervasive symbolism of drowning scenes in German Realism, which typically occur in zones of narrative invisibility on the social periphery, reveals the extent to which realist narrative uses the natural environment to work through deeply embedded and hidden tensions that troubled the social and moral life of the age.

Ancient DNA Typing
  • Language: en
  • Pages: 320

Ancient DNA Typing

This is the definitive source of information on techniques for the identification and sequencing of old DNA (pieces) and their use in biological and medical research and application. Application of aDNA techniques are useful tools for investigations reaching from evolutionary studies to law enforcement approaches. What brings them together is the interest in specific methods of handling aDNA, i.e. elaborated PCR and sequencing techniques and the interpretation of the results. This books serves as an ideal guideline for it demonstrates how problem-solving strategies can be applied in various areas.

Analytical Techniques for Clinical Chemistry
  • Language: en
  • Pages: 37

Analytical Techniques for Clinical Chemistry

Discover how analytical chemistry supports the latest clinical research This book details the role played by analytical chemistry in fostering clinical research. Readers will discover how a broad range of analytical techniques support all phases of clinical research, from early stages to the implementation of practical applications. Moreover, the contributing authors' careful step-by-step guidance enables readers to better understand standardized techniques and steer clear of everyday problems that can arise in the lab. Analytical Techniques for Clinical Chemistry opens with an overview of the legal and regulatory framework governing clinical lab analysis. Next, it details the latest progres...

Parents in the Spotlight
  • Language: en
  • Pages: 352

Parents in the Spotlight

Children and parents have become a focus of debates on ‘new social risks’ in European welfare states. Policymaking elites have converged in defining such risks, and they have outlined new forms of parenting support to better safeguard children and activate their potential. Increasingly, parents are suspected of falling short of public expectations. Contributors to this special issue scrutinize this shift towards parenting as performance and analyse recent forms of parenting support.

Interwar Vienna
  • Language: en
  • Pages: 312

Interwar Vienna

Although beset by social, political, and economic instabilities, interwar Vienna was an exhilarating place, with pioneering developments in the arts and innovations in the social sphere. Research on the period long saw the city as a mere shadow of its former imperial self; more recently it has concentrated on high-profile individual figures or party politics. This volume of new essays widens the view, stretching disciplinary boundaries to consider the cultural and social movements that shaped the city. The collapse of the Austro-Hungarian Empire resulted not in an abandonment of the arts, but rather led to new forms of expression that were nevertheless conditioned by the legacies of earlier ...