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Kinomics
Das umfassende Referenzwerk zur Kinase-Forschung: Ausführlich werden die Themen Kinase-Engineering, Peptidsubstrat-Engineering, das Design von Co-Substraten und Kinasehemmer erläutert sowie deren Anwendung in der Bio- und Pharmaforschung beschrieben.
Peptide Materials
Peptides are the building blocks of the natural world; with varied sequences and structures, they enrich materials producing more complex shapes, scaffolds and chemical properties with tailorable functionality. Essentially based on self-assembly and self-organization and mimicking the strategies that occur in Nature, peptide materials have been developed to accomplish certain functions such as the creation of specific secondary structures (a- or 310-helices, b-turns, b-sheets, coiled coils) or biocompatible surfaces with predetermined properties. They also play a key role in the generation of hybrid materials e.g. as peptide-inorganic biomineralized systems and peptide/polymer conjugates, pr...
Micro Plastics
This book focuses on the detection, extraction, remediation techniques, and future perspectives of microplastics. It includes characteristics, fluctuations, distribution, and water remediation of microplastics using various functionalized nanomaterials. This book also covers the impact of microplastics discharged from domestic and various industrial fields such as pharmaceutical, clothing, polymer industries, etc., for the quantification of poisonous substances in water. Different techniques in water remediation and environment as well as in the determination of hazard, toxicity, and monitoring standards towards microplastics are also covered. Features: Discusses the presence of microplastic...
Nanobiosensors and Nanobioanalyses
This book provides a comprehensive review of established, cutting-edge, and future trends in the exponentially growing field of nanomaterials and their applications in biosensors and bioanalyses. Part I focuses on the key principles and transduction approaches, reviewing the timeline featuring the important historical milestones in the development and application of nanomaterials in biosensors and bioanalyses. Part II reviews various architectures used in nanobiosensing designs focusing on nanowires, one- and two-dimensional nanostructures, and plasmonic nanobiosensors with interferometric reflectance imaging. Commonly used nanomaterials, functionalization of the nanomaterials, and developme...
Nanobiotechnology for Sustainable Food Management
Among the most novel and ever-growing approaches to improving the food industry is nanobiotechnology. In this book, the prospective role of nanobiotechnology in food which includes quality control and safety through nanosensors and biosensors, targeted delivery of nutrients, controlled release of nutrients, proteins, antioxidants, and flavors through encapsulation and enzymatic reactions for food fortification of fat-soluble compounds is discussed. Along the chapters of this book, nanobiotechnological techniques are addressed in detail with specific emphasis on food science applications. Features: Discusses nanobiotechnology in food for quality control and safety Covers food processing and packaging for food safety Explores the positive role of nanomaterials towards the sustainability of food Provides efficient, real, and sustainable solutions to pertinent global problems Includes case studies and research directions of the nanobiotechnology This book is aimed at researchers and graduate students in nanotechnology and food engineering.
BIOSENSORES ELECTROQUÍMICOS PARA SEGUIMIENTO MÍNIMAMENTE INVASIVO DE ENFERMEDADES DEGENERATIVAS
La enfermedad de Alzheimer es una de las enfermedades degenerativas más estudiadas y la forma más común de demencia entre las personas mayores. Para su estudio se realiza el seguimiento de distintas proteínas, las cuales se acumulan en el organismo generando la enfermedad. Con el fin de que este seguimiento pueda ser realizado por los propios cuidadores y, si es preciso, por personal no altamente cualificado en residencias, ambulatorios o en el domicilio de los pacientes, actualmente se busca desarrollar dispositivos portátiles, sensibles, fiables, precisos y económicos, que permitan alcanzar este objetivo. De acuerdo con estas características, los biosensores electroquímicos han dem...
Fusion Protein Technologies for Biopharmaceuticals
The state of the art in biopharmaceutical FUSION PROTEIN DESIGN Fusion proteins belong to the most lucrative biotech drugs—with Enbrel® being one of the best-selling biologics worldwide. Enbrel® represents a milestone of modern therapies just as Humulin®, the first therapeutic recombinant protein for human use, approved by the FDA in 1982 and Orthoclone® the first monoclonal antibody reaching the market in 1986. These first generation molecules were soon followed by a plethora of recombinant copies of natural human proteins, and in 1998, the first de novo designed fusion protein was launched. Fusion Protein Technologies for Biopharmaceuticals examines the state of the art in developing...
Kinomics
Authored by the world's leading kinase experts, this is a comprehensive introduction to current knowledge and practice within this emerging field. Following an overview of the major players and pathways that define the kinome, the major part of this work is devoted to current strategies of kinome investigation and manipulation. As such, kinase engineering, peptide substrate engineering, co-substrate design and kinase inhibitor design are discussed in detail, and their potential applications in kinome analysis and kinome-based pharmacotherapy are shown. The result is a toolbox for every kinase researcher: By addressing and comparing current approaches to the study of kinase action, both novice and established researchers will benefit from the practical knowledge contained in this invaluable reference.
