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Special features of the book We have divided every organic reaction in following subsections: It is hope that this type of presentation will greatly aid the memory and understanding of students. Principle: Includes text and general reactions with examples. We have indicated changes in functional groups while conversion of reactants into final products with the use of advanced ChemBioDraw Ultra tool. The text of manuscript has been made simple and lucid with pictorial presentations. Mechanism: Includes text and detailed stepwise mechanism by highlighting the changes in reactants at every step. The context includes beautiful and clear representation of mechanisms; each step is shown without us...
Prodrug Design: Perspectives, Approaches and Applications in Medicinal Chemistry provides a focused overview of this critical area of drug discovery, as that continuous process strives not only to discover new drug compounds but also to modify the existing ones. This valuable primer supports this mission of drug development and its goal of reducing undesired effects and improving therapeutic effectiveness of drug compounds. Providing a unique compilation of data, insightful case studies, and review of existing literature in the area, the book will promote innovation in medicinal and pharmaceutical chemistry research, exploring the limitations of existing drugs and their improvement. Prodrug Design reviews marketed compounds, the safety of promoieties, and a detailed classification of prodrugs organized by therapeutic area for easy reference. - Offers unique, detailed overview of Prodrug research and literature - Provides detailed chemical structures - Includes Prodrug listing by therapeutic area
Biochemistry, Biophysics, and Molecular Chemistry: Applied Research and Interactions provides the background needed in biophysics and molecular chemistry and offers a great deal of advanced biophysical knowledge. It emphasizes the growing interrelatedness of molecular chemistry and biochemistry, and acquaints one with experimental methods of both disciplines. This book addresses some of the enormous advances in biochemistry, particularly in the areas of structural biology and bioinformatics, by providing a solid biochemical foundation that is rooted in chemistry. Topics include scientific integrity and ethics in the field; clinical translational research in cancer, diabetes, and cardiovascular disease; emerging drugs to treat neurodegenerative diseases; swine, avian, and human flu; the use of big data in artificial knowledge in the field; bioinformatic insights on molecular chemistry; and much more.
Recent Advancement in Prodrugs Drugs used as medicines have many limitations like low chemical stability, aqueous solubility, or oral absorption/bioavailability, rapid presystemic metabolism, toxicity, inadequate site specificity, or poor patient acceptance/compliance (unwanted adverse effects, unacceptable taste or odor, irritation or pain). Prodrugs design is an approach to overcome these limitations. Key features Covers recent advancements in development of prodrugs Presents balanced synthesis and applications of prodrug chemistry Discusses broad spectrum of prodrug categories and outlines industrial applications Reviews prodrugs in cancer nanomedicine, its therapy and treatment Elucidates mathematical models to study the kinetics of prodrugs This book covers recent advances in the design of prodrugs. It contains all the significant recent examples of prodrug chemistry developments and will aid academics and researchers seeking to generate new projects in the field.
Nanobiosensors for Bio-molecular Targeting presents the latest analytical methods for the detection of different substances in the range of small molecules to whole cells, exploring the advantages and disadvantages of each method. Biosensors combine the component of biological origin and physicochemical detector to show the presence of analytes in a given sample. The use of bionanotechnology has led to a significant advancement in the progression of nanobiosensors and has been effectively used for biomedical diagnosis. - Explains the detection techniques used by nanosensors, exploring the strengths and weaknesses of each for the detection of disease - Shows how biosensors are used to detect various types of biomolecules - Demonstrates how the use of nanomaterials makes biosensors both cheaper and more efficient
The term 'Pharmacy Practice' denotes both Community Pharmacy Practice and Hospital Pharmacy practice and hence all the matters relevant to both these Practices are covered in detail to help the budding pharmacists to choose and practice the carrier of their choice. As the pharmacy practice now is more patient-oriented than product Oriented, a new branch of Clinical Pharmacy Practice is included in Hospital Pharmacy Practice and that is dealt elaborately in this book so that students of Pharm.D can also find this book useful. The book has 21 chapters in all with model questions at the end of each chapter. Sub-headings of each chapter's content are given in the contents pages so that the readers can easily locate the topic they want to read.
This book is written with a view to help undergraduate and graduate students learn the fundamental principles and applications of different types of chromatography. The authors aim to facilitate the understanding of chromatographic techniques, through description of techniques in a lucid manner. Salient features The book encompasses the basic principles of chromatography, the techniques, and description of modern hyphenated chromatographic instrumentation and applications of these techniques. This book will serve students in developing their research interests in the field of chromatography.
This 6th edition of the established textbook covers every aspect of drug properties from the design of dosage forms to their delivery by all routes to sites of action in the body.
The five volume set LNCS 10960 until 10964 constitutes the refereed proceedings of the 18th International Conference on Computational Science and Its Applications, ICCSA 2018, held in Melbourne, Australia, in July 2018. Apart from the general tracks, ICCSA 2018 also includes 34 international workshops in various areas of computational sciences, ranging from computational science technologies, to specific areas of computational sciences, such as computer graphics and virtual reality. The total of 265 full papers and 10 short papers presented in the 5-volume proceedings set of ICCSA 2018, were carefully reviewed and selected from 892 submissions.
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