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The second volume of the Biomedical translational research discusses advancements in biomedical research for understanding the pathophysiology of various diseases towards improving diagnosis and treatment. It presents the integration of molecular-based technologies, clinical genomics, and medical informatics to improve diagnostic and treatment strategies. Further, the book reviews molecular genomics approaches for diagnosis and managing tuberculosis. It also covers the innovative strategies for cancer treatment through targeting metabolic pathways, tumor microenvironment, cancer stem cells, and immune cells. It also illuminates novel strategies for heart failure diagnosis and therapeutic approaches for the treatment of heart failure. It discusses improvements in translational research for discovery of new diagnostic tests, identifying novel biomarkers and drugable targets, and predicting optimal treatments based on understanding the underlying molecular basis of the disease. Lastly, it reviews the preclinical models of restenosis and their application and limitation in the evaluation of device-based interventional technologies for the treatment of coronary artery diseases.
This book presents the select proceedings of the International Conference on Functional Material, Manufacturing and Performances (ICFMMP) 2019. The book primarily covers recent research, theories, and practices relevant to surface engineering and processing of materials. It focuses on the lesser-known technologies and advanced manufacturing methods which may not be standardized yet but are highly beneficial to material and manufacturing industrial engineers. The book includes current advances in the field of coating, deposition, cladding, nanotechnology, surface finishing, precision machining, processing, and emerging advanced manufacturing technologies which enhance the performance of materials in terms of corrosion, wear and fatigue. The book can be a valuable reference for beginners, researchers, and professionals interested in materials processing and allied fields.
The term "biodiversity" or "biological diversity" describes the variety of living beings on Earth encompassing microorganisms, plants, animals, and ecosystems, such as coral reefs, forests, and deserts. In fact, it also represents a wealth of biological resources available to us. Today, instead of exploring and preserving its unmapped biodiversity, mankind has gone away from mother nature, conquering the domain through relentless exploitation. This has resulted in an ecological imbalance and thereby has posed serious threat to biodiversity. Declining biodiversity is, therefore, a concern for countless reasons. Biodiversity’s wealth of genetic information can be conserved by storing biologi...
BollySwar is a decade-wise compendium of information about the music of Hindi films. Volume 8 chronicles the Hindi film music of the decade between 2001 and 2010. This volume catalogues more than 1000 films and 8000 songs, involving more than 2000 music directors, lyricists and singers. An overview of the decade highlights the key artists of the decade - music directors, lyricists and singers - and discusses the emerging trends in Hindi film music. A yearly review provides listings of the year's top artists and songs and describes the key milestones of the year in Hindi film music. The bulk of the book provides the song listing of every Hindi film album released in the decade. Basic informat...
In this second edition of his highly acclaimed book, Christopher P. Cannon, MD, and a team of preeminent clinical investigators have thoroughly revised and expanded every chapter to reflect the recent explosion of clinical trials on the management of acute coronary syndromes (ACS). This includes: the newer tests, such as C reactive protein; a multimarker approach to diagnosis and risk stratification; new antiplatelet agents; and combinations of thrombolytic-antithrombotic regimens. Also discussed are the latest developments in interventional cardiology, the use of cost-effectiveness in clinical trials to choose appropriate therapies, and the employment of critical pathways analysis to improve compliance with evidence-based medicine and guideline recommendations.
The book explores the fundamental principles, advances in forensic techniques, and its application on forensic DNA analysis. The book is divided into three modules; the first module provides the historical prospect of forensic DNA typing and introduces fundamentals of forensic DNA typing, methodology, and technical advancements, application of STRs, and DNA databases for forensic DNA profile analysis. Module 2 examines the problems and challenges encountered in extracting DNA and generating DNA profiles. It provides information on the methods and the best practices for DNA isolation from forensic biological samples and human remains like ancient DNA, DNA typing of skeletal remains and disast...
Biomedical research is the first step towards the creation of new medications and treatments that help to manage different types of health conditions and diseases. The prevention and cure of diseases would be practically impossible without such type of research. Although the drug discovery and development processes are far too costly, time-consuming, prone to failure, and have low success rate, today the term "translational research or medicine" seems to have become trendy, yet it is insufficient. The present book is a sincere attempt by dedicated researchers to convey the importance of translational biomedical research, medicine, and disease, primarily, basic and clinical difficulties in th...
ProjectX India | 15th July 2021 edition provides you with power-packed information on 246 projects from 66 sectors of the Indian economy. In this issue we have covered 43 projects in Conceptual/Planning Stage, 48 Contract Awards, 42 Projects Under Implementation, 104 Tenders, and 9 other projects. The project information is provided along with nearest contacts as available in the public domain to facilitate B2B exchange. Each issue of ProjectX India series provides you with information on new projects & ongoing projects from India, Contract Awards, Project Updates, Commissioned Projects and Tenders. This e-book serves to all those who are interested to know and tap the project opportunities in the Construction, Infrastructure, and Industrial segment. The aim is to serve you with the right information on upcoming and ongoing projects, contracts, and tenders from India. The business opportunities are coming to the fore each day, and we, at ProjectX India, are eager to grab and provide the information which can make a difference to your business. Identify the right project through ProjectX India and accelerate your business. Thank You and Happy Reading.
This book presents drug repurposing strategies to combat infectious diseases and cancer. It discusses key experimental and in silico approaches for modern drug repositioning, including signature matching, molecular docking, genome-wide associated studies, and network-based approaches aided by artificial intelligence. Further, the book presents various computational and experimental strategies for better understanding disease mechanisms and identify repurposed drug candidates for personalized pharmacotherapy. It also explores the databases for drug repositioning, summarizes the approaches taken for drug repositioning, and highlights and compares their characteristics and challenges. Towards the end, the book discusses challenges and limitations encountered in computational drug repositioning.
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