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Molecular Aspects of Hematologic Malignancies
This book provides a state-of-the-art approach to the molecular basis of hematologic diseases and its translation into improved diagnostics and novel therapeutic strategies. Several representative hemato-oncologic malignancies are analyzed in detail: acute lymphoblastic leukemia, acute myeloid leukemia, B-cell Non-Hodgkin lymphomas, multiple myeloma, chronic lymphocytic leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. Experts in the field describe the molecular methods applied for modern diagnostics and therapies, such as hematopoietic stem cell transplantation, donor recipient matching, banking of biological material, analyses of post-transplant chimerism, and minimal residual disease monitoring. The volume concludes with an extensive section comprising thorough step-by-step protocols of molecular techniques in hematology, all of them validated in the authors’ own laboratories.
Ethnopharmacology
Ethnopharmacology is one of the world’s fastest-growing scientific disciplines encompassing a diverse range of subjects. It links natural sciences research on medicinal, aromatic and toxic plants with socio-cultural studies and has often been associated with the development of new drugs. The Editors of Ethnopharmacology have assembled an international team of renowned contributors to provide a critical synthesis of the substantial body of new knowledge and evidence on the subject that has emerged over the past decade. Divided into three parts, the book begins with an overview of the subject including a brief history, ethnopharmacological methods, the role of intellectual property protectio...
Flow Cytometry
"Flow Cytometry - Recent Perspectives" is a compendium of comprehensive reviews and original scientific papers. The contents illustrate the constantly evolving application of flow cytometry to a multitude of scientific fields and technologies as well as its broad use as demonstrated by the international composition of the contributing author group. The book focuses on the utilization of the technology in basic sciences and covers such diverse areas as marine and plant biology, microbiology, immunology, and biotechnology. It is hoped that it will give novices a valuable introduction to the field, but will also provide experienced flow cytometrists with novel insights and a better understanding of the subject.
Selected Topics of Computational and Experimental Fluid Mechanics
This book contains invited lectures and selected contributions presented at the Enzo Levi and XIX Annual Meeting of the Fluid Dynamic Division of the Mexican Physical Society in 2013. It is aimed at fourth year undergraduate and graduate students, and scientists in the fields of physics, engineering and chemistry who are interested in fluid dynamics from an experimental and theoretical point of view. The invited lectures are introductory and avoid the use of complicated mathematics. The fluid dynamics applications include multiphase flow, convection, diffusion, heat transfer, rheology, granular material, viscous flow, porous media flow, geophysics and astrophysics. The material contained in the book includes recent advances in experimental and theoretical fluid dynamics and is suitable for both teaching and research.
Unfolding Cluster Evolution
Various theories have been put forward as to why business and industry develops in clusters and despite good work being carried out on path dependence and dynamics, this is still very much an emerging topic in the social sciences. To date, no overarching theoretical framework has been developed to show how clusters evolve. Unfolding Cluster Evolution aims to address this gap by presenting theoretical and empirical research on the geography of innovation. This contributed volume seeks to shed light on the understanding of clusters and its dynamic evolution. The book provides evidence to suggest that traditional perspectives from evolutionary economic geography need to be wedded to management thinking in order to reach this point. Bringing together thinking from a range of disciplines and countries across Europe, this book explores a wide range of topics from the capability approach, to network dynamics, to multinational corporations, to firm entry and exit and social capital. This book will be of interest to policy makers and students of urban studies, economic geography, and planning and development.
More Argentine Than You
Whether in search of adventure and opportunity or fleeing poverty and violence, millions of people migrated to Argentina in the nineteenth and early twentieth centuries. By the late 1920s Arabic speakers were one of the country’s largest immigrant groups. This book explores their experience, which was quite different from the danger and deprivation faced by twenty-first-century immigrants from the Middle East. Hyland shows how Syrians and Lebanese, Christians, Jews, and Muslims adapted to local social and political conditions, entered labor markets, established community institutions, raised families, and attempted to pursue their individual dreams and community goals. By showing how societies can come to terms with new arrivals and their descendants, Hyland addresses notions of belonging and acceptance, of integration and opportunity. He tells a story of immigrants and a story of Argentina that is at once timely and timeless.
Advances in Malignant Hematology
This comprehensive book captures and compiles new and current information on hematologic malignancies. New knowledge of cellular disease processes, molecular pathology, and cytogenetic, epigenetic and genomic changes has influenced the current outlook toward haematological malignancies. This recent and ongoing expansion of knowledge on malignant hematology has not previously been utilized to its full capacity due to its diffuse distribution scattered over the internet and research publications. This book is written by experts from the American and European continent, sharing their current thoughts and knowledge on the pathobiology of malignant haematological diseases of the blood, as well as current treatment strategies and future developments in the area of these haematological diseases.
Pedro de Valencia and the Catholic Apologists of the Expulsion of the Moriscos
The Spanish Moriscos, Muslims forcibly converted to Christianity, were expelled by Philip III between 1609 and 1614. Subsequently, writers known as Catholic Apologists wrote justifying the event. Pedro de Valencia, humanist, biblical scholar, jurist and royal Chronicler, condemned expulsion. Both Apologists and Pedro de Valencia made their case by invoking Divine Providence: the former contended that millenarian prophecies and apocalyptic visions were signs of divine warning beforehand and of approval afterwards; Valencia urged Philip III to act as a shepherd king, arguing that Divine Providence would punish monarchs who put political expediency before moral rectitude. Drawing on unpublished source material, the book juxtaposes the ideals of Valencia, a Christian humanist, with the bigotry, superstition and racism of the Apologists.
Three Essays on the Times and Work of Tomás de Mercado
The purpose of this edition is to provide an English translation of three essays about Tomás de Mercado’s book, Deals and Contracts of Merchants and Traders. This translation has been made from the 1569 edition of the book published in Salamanca. The book was later the object of new editions and it was expanded by two more chapters, with an Italian translation appearing in 1571. However, an English edition had never been made before. The 1569 edition is composed of four Books: the first dedicated to merchants and their contracts, the second to currency and loans, the third to usury and the fourth to the question of the obligation of restitution when a reprehensible action is committed.
