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This issue covers the latest developments in the understanding of rheumatoid arthritis at the early stage. Treatments such as with newer biologic agents and conventional disease-modifying antirheumatic drugs are reviewed. Also included are articles on imaging modalities as a means of identifying those in the early stages and monitoring response to treatment.
Artificial Intelligence Medicine: Technical Basis and Clinical Applications presents a comprehensive overview of the field, ranging from its history and technical foundations, to specific clinical applications and finally to prospects. Artificial Intelligence (AI) is expanding across all domains at a breakneck speed. Medicine, with the availability of large multidimensional datasets, lends itself to strong potential advancement with the appropriate harnessing of AI. The integration of AI can occur throughout the continuum of medicine: from basic laboratory discovery to clinical application and healthcare delivery. Integrating AI within medicine has been met with both excitement and scepticis...
Table 1 Cancer is the second most common cause of death in Americans (see www.cdc.gov). Colorectal cancer kills more Incidence and Mortality of the Five Most Common Gastrointestinal Malignancies Americans than any other malignancy except for lung cancer. The incidences and mortalities of the major gastrointestinal a a Site Incidence Mortality (GI) malignancies are shown in Table 1. Taken as a group, the five most common GI malignancies account for more cancers Colorectum 53.9 21.6 and more cancer deaths than for any other site. Pancreas 11.1 10.6 Stomach 9.1 4.9 Flexible endoscopy has given physicians unprecedented Liver/intrahepatic bile ducts 6.2 4.4 access to the GI tract. The ability to endoscopically visu- Esophagus 4.5 4.3 alize, biopsy, and apply therapy has had implications for the management of all the major GI malignancies. Accepted Data from SEER database 1992–2002 (www.seer.cancer.gov). applications of endoscopy range from detection of mal- a Per 100,000.
The Grants Register 2020 is the most authoritative and comprehensive guide available of postgraduate and professional funding worldwide. It contains international coverage of grants in almost 60 countries, both English and non-English speaking; information on subject areas, level of study, eligibility and value of awards; and information on over 6,000 awards provided by over 1,300 awarding bodies. Awarding bodies are arranged alphabetically with a full list of awards to allow for comprehensive reading. The Register contains full contact details including telephone, fax, email and websites as well as details of application procedures and closing dates. It is updated annually to ensure accurate information.
Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.
This book includes selecting the articles accepted for presentation and discussion at WCQR2021, held on January 20th to 22nd, 2021 (Virtual Conference). The World Conference on Qualitative Research (WCQR) is an annual event that aims to bring together researchers, academics and professionals, promoting the sharing and discussion of knowledge, new perspectives, experiences and innovations on Qualitative Research. WCQR2021 featured four main application fields (Education, Health, Social Sciences, and Engineering/Technology) and seven main subjects: Rationale and Paradigms of Qualitative Research; Systematization of Approaches with Qualitative Studies; Qualitative and Mixed Methods Research; Data Analysis Types; Innovative Processes of Qualitative Data Analysis; Qualitative Research in Web Context; Qualitative Analysis with Software Support. The book is a valuable resource for everyone interested in qualitative research, emphasizing Computer-Assisted Qualitative Data Analysis Software (CAQDAS).
Comprehensive in scope and invaluable for both practitioners and students, Mechanisms and Management of Pain for the Physical Therapist, 2nd Edition, thoroughly covers the wide range of issues requiring the interdisciplinary management of pain. Joined by more than 20 international contributors, Dr. Kathleen Sluka provides a practical, evidence-based framework for understanding the basics of pain mechanisms and management. This highly regarded, updated text covers the basics of pain neurobiology and reviews evidence on the mechanisms of action of physical therapy treatments, as well as their clinical effectiveness in specific pain syndromes.
The introduction of clinical governance gives National Health Service organisations a powerful incentive to focus on serious failures in health care. This report reviews what is known about the scale and nature of these failures, examining the extent to which the NHS has the capacity to learn from them when they do occur, and recommending measures which could help to minimise the likelihood of repeated failures in service in the future. Information was drawn from industry, aviation and academic research.