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ROS were long considered one of the key players in tissue injury. Indeed, overproduction of ROS results in oxidative stress, a process leading to the development of many pathological conditions. For the treatment of these conditions, the use of antioxidants was proposed. Over time, it was shown that ROS at low concentrations act as signaling molecules, leading to the regulation of physiological functions. Moreover, several interventions that increase ROS generation activate stress-adaptive responses that extend the lifespan. It was also shown that excessive use of antioxidants can counter the beneficial effects of ROS. Currently, much progress has been made in understanding the role of ROS i...
UNLIMITED HAPPINESS AND ETERNAL LIFE One is a fool’s errand and the other a distinct possibility. In this data-driven survival guide, Dr. Bob Nguyen takes you on a whirlwind campaign that covers these endeavors and much more. From building awareness and managing expectations, to life repurposing and fostering relationships, to adopting the latest anti-ageing and longevity biohacks, this book delivers a practical, actionable and wide-ranging response to the common calamity that is midlife crisis. In these pages, Nguyen first describes turmoil typical of each decade of life, detailing how COVID took the crisis out of midlife and made it a transgenerational pandemic. Suddenly, adults of all a...
ROS were long considered one of the key players in tissue injury. Indeed, overproduction of ROS results in oxidative stress, a process leading to the development of many pathological conditions. For the treatment of these conditions, the use of antioxidants was proposed. Over time, it was shown that ROS at low concentrations act as signaling molecules, leading to the regulation of physiological functions. Moreover, several interventions that increase ROS generation activate stress-adaptive responses that extend the lifespan. It was also shown that excessive use of antioxidants can counter the beneficial effects of ROS. Currently, much progress has been made in understanding the role of ROS i...
For many centuries, fenugreek has been one of the most popular spices and vegetables serving as an integral part of culinary practices across many cultures. Fenugreek contains exceptional nutritional and medicinal properties, but scientific evidence for its potential health benefits has been considerably understudied and is beginning to grow. This book is a comprehensive compilation and documentation on the scientific profile of fenugreek and its phytoconstituents, including their most known applications and health benefits. It features a wide range of chapters written by highly experienced academics and industrial professionals. Topics cover applications of fenugreek including information o...
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This book presents the latest, innovative research findings on P2P, Parallel, Grid, Cloud, and Internet Computing. It gathers the Proceedings of the 12th International Conference on P2P, Parallel, Grid, Cloud and Internet Computing, held on November 8–10, 2017 in Barcelona, Spain. These computing technologies have rapidly established themselves as breakthrough paradigms for solving complex problems by enabling the aggregation and sharing of an increasing variety of distributed computational resources at large scale. Grid Computing originated as a paradigm for high-performance computing, offering an alternative to expensive supercomputers through different forms of large-scale distributed c...