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Lumpy Skin Disease
  • Language: en

Lumpy Skin Disease

  • Type: Book
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  • Published: 2018
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  • Publisher: Unknown

This book provides a comprehensive but concise overview on the economically important emerging cattle pox virus derived Lumpy Skin Disease, including the characteristics of causative agent, description of clinical signs in cattle, pathology and histopathology, immunity, geographical distribution, epidemiology and transmission pathways, control and eradication of the disease. In addition the recent developments in vaccination, mathematical modeling and risk assessment are discussed. Lumpy Skin Disease currently spreads aggressively across the Middle and Near East. The first incursion to the European Union territory occurred in Greece in autumn 2015. The book targets clinicians and field veterinarians in Lumpy Skin Disease affected regions, veterinary authorities as well as advanced students in veterinary medicine and virology.

Delivery of Polynucleotides and Oligonucleotides for Improving Immune Responses to Vaccines
  • Language: en

Delivery of Polynucleotides and Oligonucleotides for Improving Immune Responses to Vaccines

  • Type: Book
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  • Published: 2003
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  • Publisher: Unknown

None

Emerging Arboviruses
  • Language: en
  • Pages: 276

Emerging Arboviruses

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DNA Vaccines
  • Language: en
  • Pages: 382

DNA Vaccines

In the early 1990s, almost 200 yr after Edward Jenner demonstrated the effectiveness of the smallpox vaccine, a new paradigm for vaccination emerged. The conventional method of vaccination required delivery of whole pathogens or structural subunits, but in this new approach, DNA or genetic information was administered to elicit an immunological response. Once it was observed that plasmid DNA delivered in vivo led to production of an encoded transgene (1), two ground-breaking studies demonstrated that immunological responses could be generated against antigenic transgenes via plasmid DNA delivered by DNA vaccination (as this approach is called) (2,3). The appe- ance of this new vaccination st...

Delivery of Polynucleotides and Oligonucleotides for Improving Immune Responses to Vaccines
  • Language: en

Delivery of Polynucleotides and Oligonucleotides for Improving Immune Responses to Vaccines

  • Type: Book
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  • Published: 2003
  • -
  • Publisher: Unknown

Vaccination is one of the major achievements of modern medicine. As a result of vaccination, diseases such as polio and measles have been controlled and small pox has been eliminated. However, despite these successes there are still many diseases of microbial origin that cause tremendous suffering because there are no vaccines or the vaccines available are inadequate. The development of DNA based vaccines and immunostimulatory CpG oligonucleotides (ODNs) as adjuvants offer new possibilities for developing new vaccines. The objectives of this research were to improve the delivery of polynucleotides and oligonucleotides to enhance their potency and to evaluate the feasibility of non-invasive m...

Lumpy Skin Disease
  • Language: en
  • Pages: 99

Lumpy Skin Disease

  • Type: Book
  • -
  • Published: 2018-07-03
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  • Publisher: Springer

This book provides a comprehensive but concise overview on the economically important emerging cattle pox virus derived Lumpy Skin Disease, including the characteristics of causative agent, description of clinical signs in cattle, pathology and histopathology, immunity, geographical distribution, epidemiology and transmission pathways, control and eradication of the disease. In addition the recent developments in vaccination, mathematical modeling and risk assessment are discussed. Lumpy Skin Disease currently spreads aggressively across the Middle and Near East. The first incursion to the European Union territory occurred in Greece in autumn 2015. The book targets clinicians and field veterinarians in Lumpy Skin Disease affected regions, veterinary authorities as well as advanced students in veterinary medicine and virology.

Viral Vectors in Veterinary Vaccine Development
  • Language: en
  • Pages: 232

Viral Vectors in Veterinary Vaccine Development

This highly accessible textbook introduces readers to the development of viral vectors and discusses their application in veterinary vaccinology. It offers comprehensive information on the latest advances in this emerging research field, together with a broad overview of the history of veterinary vaccines and viral vectors. The book also addresses issues concerning funding, translational research and ethics that will impact the future development, manufacture and global use of viral vector-based veterinary vaccines. The book addresses the needs of graduate students and researchers in the fields of Veterinary Medicine, Virology and Immunology. ​

Pathogen Transmission at the Domestic-Wildlife Interface: A Growing Challenge that Requires Integrated Solutions
  • Language: en
  • Pages: 144

Pathogen Transmission at the Domestic-Wildlife Interface: A Growing Challenge that Requires Integrated Solutions

Over thousands of years, wildlife has coexisted with domestic animals in dynamic systems. The domestic-wildlife interfaces are those physical spaces where wild and domestic species overlap and potentially interact through direct and indirect contact, with the inherent risk of pathogen transmission. The nature of this interface is complex and can significantly vary over time and across landscapes throughout the world. Over the last centuries, processes such as human intervention on agriculture and animal husbandry, industrialization, or globalization have altered ecosystems. These changes often lead to more interconnected interfaces and increased opportunities for the emergence and spread of pathogens because the human population is increasing and expanding, livestock production is therefore increasing to supply the growing food demand, and wildlife, often under the pressure of habitat reduction, is becoming more exposed to these new interfaces.

New-generation vaccines and novel vaccinal strategies against infectious diseases of livestock, wild and companion animals
  • Language: en
  • Pages: 128

New-generation vaccines and novel vaccinal strategies against infectious diseases of livestock, wild and companion animals

Emerging and re-emerging infections, in particular those caused by viruses, are expected to rise in correlation, among other factors, with climate changes. Antibiotic resistance is another issue that will limit the therapeutic arsenal against bacterial and parasitic infections. Therefore, one must be adequately prepared to overcome and prevent current and novel infections, and vaccination remains the optimal way to fight infectious diseases in humans. This is also true for many impacting diseases of livestock and companion animals, to which there are no available vaccines. First (attenuated and inactivated) and second (subunit) generation vaccines have their limitations. To overcome this, ef...

Emerging Infectious Diseases
  • Language: en
  • Pages: 1056

Emerging Infectious Diseases

  • Type: Book
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  • Published: 2007
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  • Publisher: Unknown

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