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Supramolecular Structure and Function 9
  • Language: en
  • Pages: 318

Supramolecular Structure and Function 9

The book is based on International Summer Schools on Biophysics held in Croatia which, contrary to other workshops centered mainly on one topic or technique, has very broad scope providing advanced training in areas related to biophysics. This volume presents papers in the field of biophysics for studying biological phenomena by using physical methods and/or concepts. Its scope should be of interest for students at doctoral or postdoctoral level and to experienced scientists.

Systems Analysis of Chromatin-Related Protein Complexes in Cancer
  • Language: en
  • Pages: 320

Systems Analysis of Chromatin-Related Protein Complexes in Cancer

​​​​​​​​​​​​​​​​​​​​​​​ Epigenetic modifications underlie all aspects of human physiology, including stem cell renewal, formation of cell types and tissues. They also underlie environmental impacts on human health, including aging and diseases like cancer. Consequently, cracking the epigenetic "code" is considered a key challenge in biomedical research. Chromatin structure and function are modified by protein complexes, causing genes to be turned “on” or “off” and controlling other aspects of DNA function. Yet while there has been explosive growth in the epigenetics field, human chromatin-modifying machines have only recently started to b...

Reviews in Computational Chemistry, Volume 28
  • Language: en
  • Pages: 570

Reviews in Computational Chemistry, Volume 28

The Reviews in Computational Chemistry series brings together leading authorities in the field to teach the newcomer and update the expert on topics centered around molecular modeling, such as computer-assisted molecular design (CAMD), quantum chemistry, molecular mechanics and dynamics, and quantitative structure-activity relationships (QSAR). This volume, like those prior to it, features chapters by experts in various fields of computational chemistry. Topics in Volume 28 include: Free-energy Calculations with Metadynamics Polarizable Force Fields for Biomolecular Modeling Modeling Protein Folding Pathways Assessing Structural Predictions of Protein-Protein Recognition Kinetic Monte Carlo Simulation of Electrochemical Systems Reactivity and Dynamics at Liquid Interfaces

Protein Modules and Protein-Protein Interactions
  • Language: en
  • Pages: 343

Protein Modules and Protein-Protein Interactions

  • Type: Book
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  • Published: 2002-11-24
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  • Publisher: Elsevier

Protein modules engage in a multitude of interactions with one another and with other cellular components, notably with DNA. These interactions are a central aspect of protein function of great relevance in the post-genomic era. This volume describes a panel of approaches for analyzing protein modules and their interactions, ranging from bioinformatics to physical chemistry, to biochemistry, with an emphasis on the structure-function relationship in protein-protein complexes involved in cellular processes including signal transduction. - Comprehensive overview of different facets of macromolecule interactions - Computational and bioinformatics aspects of analyzing protein modules and their interactions - Emphasis on structure-function relationship in protein-protein complexes involved in cellular processes

Leadership in Science and Technology: A Reference Handbook
  • Language: en
  • Pages: 985

Leadership in Science and Technology: A Reference Handbook

  • Type: Book
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  • Published: 2011-10-20
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  • Publisher: SAGE

Tackling 100 key topics and providing case studies in the area of science and technology leadership, this reference handbook is an essential resource for students in this area.

Artemia Biology
  • Language: en
  • Pages: 385

Artemia Biology

  • Type: Book
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  • Published: 2018-01-18
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  • Publisher: CRC Press

Artemia is widely used in both life-sciences research and aquaculture. Although there are over 4000 references regarding Artemia, the literature is widely scattered. Artemia Biology provides a comprehensive, state-of-the-art review of this literature, containing a considerable amount of previously unpublished data. Although all aspects of Artemia biology are covered, the book emphasizes whole-organism approaches. Topics covered include molecular genetics, ontogeny, clonal diversity, mitochondrial DNA-based phylogeny, and comparisons of Artemia and Parartemia (including a taxonomic key to Parartemia species). The book also contains the latest information on Artemia culturing in fertilized ponds and culture tanks, as well as the use of the organism as a food source. Researchers investigating basic biological questions involving molecular genetics, biochemistry, enzymatic and developmental activities, physiology, ecological genetics and adaptation, ecology, and aquaculture production will find this book indispensable.

Environmental Effects on Molecular Structure and Properties
  • Language: en
  • Pages: 577

Environmental Effects on Molecular Structure and Properties

The holding of the 8th Jerusalem Symposium was saddened by the sudden death of Professor Ernst D. Bergmann at the very eve of this meeting. With him disappeared one of the leading world scientists in the field of physical chemistry and biochemistry. His innumerable friends and admirers over the whole world mourn him profoundly. All those who knew him personally and among them the participants in the previous Jerusalem Symposia will remember for ever the exceptional qualities of the scientist and the unusual human warmth of the man. With Ernst D. Bergmann the state of Israel lost one of the founders of its Science and one of its most brilliant and renowned representatives. The spirit which he...

Computer Modelling in Molecular Biology
  • Language: en
  • Pages: 259

Computer Modelling in Molecular Biology

This book supplies an application-oriented introduction to molecular simulation techniques used to study a wide range of problems in molecular biology. Each chapter focuses in detail on one kind of application, including the scientific background, the appropriate methodology and the relationship to experimental results. The book contains many areas of interest to basic and industrial scientists, including: - flexibility of peptides - protein-peptide interactions - ion translocation across membranes - modelling protein and nucleic acid conformations - stability of mutant proteins - modelling conformational transitions Currently the only up-to-date compilation available, this book enables readers to get an overview of the methods and how they are used in various specialized applications without having to search for them in a large number of papers in different journals.

Data Management of Protein Interaction Networks
  • Language: en
  • Pages: 145

Data Management of Protein Interaction Networks

Current PPI databases do not offer sophisticated querying interfaces and especially do not integrate existing information about proteins. Current algorithms for PIN analysis use only topological information, while emerging approaches attempt to exploit the biological knowledge related to proteins and kinds of interaction, e.g. protein function, localization, structure, described in Gene Ontology or PDB. The book discusses technologies, standards and databases for, respectively, generating, representing and storing PPI data. It also describes main algorithms and tools for the analysis, comparison and knowledge extraction from PINs. Moreover, some case studies and applications of PINs are also discussed.

Advances in Technological Applications of Logical and Intelligent Systems
  • Language: en
  • Pages: 296

Advances in Technological Applications of Logical and Intelligent Systems

  • Type: Book
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  • Published: 2009
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  • Publisher: IOS Press

Contains papers on relevant technological applications of logical methods and some of their extensions and gives an idea of some applications of logical methods to numerous problems, including relevant concepts and results, in particular those related to paraconsistent logic.