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Die Domstadt Köln hält den Atem an, als eine grausam zugerichtete Leiche gefunden wird. Aufgebahrt wie ein Engel, das Herz herausgetrennt. Der Täter hat keine Spuren hinterlassen und beinahe scheint es, als ginge ein blutrünstiges Phantom um. Als Sascha und sein Team die Ermittlungen aufnehmen, wird schnell klar, hier ist ein Serienmörder mit viel Liebe zum Detail am Werk. Je näher sie ihm kommen, desto schneller und brutaler schlägt er zu. Erst viel zu spät bemerkt Sascha, dass der "Geist" mit ihm spielt - ein Spiel, das für ihn tödlich enden soll.
Adaptable Architecture
Adaptable Architecture provides thought-provoking and inquisitive insights into how we can prolong the useful life of buildings by designing them to be more adaptable, and hence create a more sustainable built environment. The book provides a theoretical foundation counterpointed by the experiences and ideas of those involved in the design and use of buildings. It explains many approaches to designing for change, with lessons from history, and case studies including The Cedar Rapids Public Library, Kentish Town Health Centre and Folkestone Performing Arts Centre, which stretch our thinking beyond the conventional notions of adaptability. The authors reveal the many conditions that make it a ...
Textbook of Clinical Embryology
The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.
IVF in the Medically Complicated Patient
There is a unique set of circumstances affecting treatment for every patient involved in assisted reproduction, and those with pre-existing medical conditions, or those receiving medical therapies that may impact on the safety and success of their IVF treatment, are particularly challenging. Providing a concise but authoritative source of informati
Culture Media, Solutions, and Systems in Human ART
Detailed discussion of the history, current status and significance of ART media and the culture systems for their use.
Infertility in the Male
This extensively revised edition of the highly-respected reference book provides in-depth discussions on the latest developments in male reproductive medicine.
Textbook of Bladder Cancer
A comprehensive reference, drawing on the expertise of international leaders in the field, this text covers everything from epidemiology, pathology, and diagnosis to the treatment of both superficial and invasive bladder cancers . The book contains over 300 to quality illustrations.
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Oogenesis
The oocyte is the largest and most mysterious cell in the body of mammalian organisms. Through its growth and maturation, it reaches extreme levels of specialization, while maintaining at the same time a condition of totipotency. Its unique ability, in co-operation with the spermatozoon, to give rise to a fully developed organism formed from hundreds of different tissues and myriads of individual cells has inspired intellectuals of all ages. Oogenesis finds impetus and purpose in casting scientific perspective towards this unique cell for the benefit of scientists and assisted reproductive technology (ART) specialists. The authors of the chapters are distinguished authorities in their respective areas of competence. From the opening of the book the reader is lead on a fantastic voyage from the formation of the primordial oocyte to the development of the early embryo, passing through crucial processes of oogenesis, such as co-ordination of oocyte and follicle growth, gene expression and organelle reorganization during growth and maturation, epigenetic mechanisms, regulation of meiosis, totipotency, cell polarity, oogenesis in vitro and maternal regulation of early development.
The Principles of Clinical Cytogenetics
In the summer of 1989, one of us (SLG), along with his mentor, Dorothy Warb- ton, attended the Tenth International Workshop on Human Gene Mapping. The me- ing was held at Yale University in celebration of the first such event, which also took place there. This meeting was not open to the general public; one had to have contributed to mapping a gene to be permitted to attend. The posters, of course, were therefore all related to gene mapping, and many were covered with pretty, colorful pictures of a novel, fluorescent application of an old technology, in situ hybridization. Walking through the room, Dorothy remarked that, because of this new FISH technique, ch- mosomes, which had become yeste...
