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New Trends in Cross-Coupling
  • Language: en
  • Pages: 914

New Trends in Cross-Coupling

Following on from its recognition in the 2010 Nobel Prize for Chemistry, contributors from across the globe present the latest cross-coupling trends in both academia and industry.

Synthetic Methods in Drug Discovery
  • Language: en
  • Pages: 474

Synthetic Methods in Drug Discovery

The number of available synthetic methods can be overwhelming. In order to create novel motifs and templates which confer new and potentially valuable drug-like properties, it is important to know which synthetic methodologies will give the best results. Similarly, which methodologies are used to progress potential drug candidates from leads through the development process? What are the current industrial research problems and how can they be resolved in an industrial setting? This book highlights key methods that have real impact in drug discovery and facilitate delivery of drug molecules. Synthetic Methods in Drug Discovery Volume 1 focuses on the hugely important area of transition metal ...

Modern Amination Methods
  • Language: en
  • Pages: 285

Modern Amination Methods

Organic compounds containing amino groups are at the center of modern organic chemistry, and are widely used in the pharmaceutical industry, crop protection, natural product chemistry, and in advanced materials. Modern methods for the introduction of the amino group are therefore of major importance to synthetic chemists and product developers. Over the last decade, many methods have been developed to generate new C-N bonds. At the same time, the pharmaceutical and chemical industry was rapidly moving away from the development of racemic compounds to the direct synthesis of enantiomerically pure materials. The articles of this book, written by internationally recognized experts, thus focus on asymmetric synthesis. The most recent catalytic amination methods have particularly revolutionized the chemistry of amino compounds - and you find them all in this first comprehensive overview.

Sustainable Chemistry
  • Language: en
  • Pages: 506

Sustainable Chemistry

Focussing on catalysis through non-endangered metals, this book is an important reference for researchers working in catalysis and green chemistry.

Organometallic Chemistry
  • Language: en
  • Pages: 516

Organometallic Chemistry

Organometallic chemistry is an interdisciplinary science which continues to grow at a rapid pace. Although there is continued interest in synthetic and structural studies the last decade has seen a growing interest in the potential of organometallic chemistry to provide answers to problems in catalysis synthetic organic chemistry and also in the development of new materials. This Specialist Periodical Report aims to reflect these current interests reviewing progress in theoretical organometallic chemistry, main group chemistry, the lanthanides and all aspects of transition metal chemistry. Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major ...

Carbon-carbon, Carbon-nitrogen and Carbon-sulfur Bond Formation Reactions
  • Language: en
  • Pages: 268

Carbon-carbon, Carbon-nitrogen and Carbon-sulfur Bond Formation Reactions

The construction of C-X (X = C, N, S) bonds is an important research content in the field of organic synthesis and drug preparation. Focusing on the green construction of the core skeleton of functional fine chemicals, the team has carried out research on green synthesis and catalytic reactions of fine chemicals, realized the effective synthesis of high value-added fine chemicals, and obtained a series of new systems of transition metal palladium and copper-catalyzed halogenated aromatic hydrocarbons involved in C-C and C-N coupling reactions; realized the efficient preparation of biphenyl, arylamine and aryl thioether compounds using water as solvent. Aiming at atomic economy, we realized t...

Advanced Organic Chemistry
  • Language: en
  • Pages: 988

Advanced Organic Chemistry

Concentrating on the most important reactions used for organic synthesis, this upper-level textbook presents the material by reaction type. The final chapter discusses the planning and execution of multi-step synthesis.

C-H and C-X Bond Functionalization
  • Language: en
  • Pages: 489

C-H and C-X Bond Functionalization

This book covers the latest research on transition-metal mediated aromatic C-H and C-X functionalizations with a focus on the two main metals most widely used to achieve cross coupling transformations.

Transition Metal Reagents and Catalysts
  • Language: en
  • Pages: 500

Transition Metal Reagents and Catalysts

Transition Metal Reagents and Catalysts Innovations in Organic Synthesis Jiro Tsuji Emeritus Professor, Tokyo Institute of Technology, Japan Numerous innovative and practical synthetic methods using transition metal complexes as either catalysts or reagents have been developed over the last 35 years. Transition Metal Reagents and Catalysts combines the varied applications of transition metal complexes in a unique and timely book in this rapidly advancing area of organic synthesis. This text is an easily understandable and enjoyable read for organic chemists who are not yet familiar with organo-transition metal chemistry. Transition Metal Reagents and Catalysts presents: * Complete coverage o...

Organometallic Chemistry
  • Language: en
  • Pages: 566

Organometallic Chemistry

Organometallic chemistry is an interdisciplinary science which continues to grow at a rapid pace. Although there is continued interest in synthetic and structural studies the last decade has seen a growing interest in the potential of organometallic chemistry to provide answers to problems in catalysis synthetic organic chemistry and also in the development of new materials. This Specialist Periodical Report aims to reflect these current interests reviewing progress in theoretical organometallic chemistry, main group chemistry, the lanthanides and all aspects of transition metal chemistry. Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major ...