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The Actin Cytoskeleton and Bacterial Infection
This volume describes the mechanisms which bacteria have created to secure their survival, proliferation and dissemination by subverting the actin cytoskeleton of host cells. Bacteria have developed a veritable arsenal of toxins, effector proteins and virulence factors that allow them to modify the properties of the intracellular actin cytoskeleton for their own purposes. Bacterial factors either modify actin directly as the main component of this part of the cytoskeleton or functionally subvert regulatory or signalling proteins terminating at the actin cytoskeleton. In short, this volume provides an overview of the various tricks bacteria have evolved to “act on actin” in order to hijack this essential host cell component for their own needs. As such, it will be of interest to scientists from many fields, as well as clinicians whose work involves infectious diseases.
Network North
Discussing a series of economic, confessional, political and espionage networks, this volume provides an illuminating study of network history in Northern Europe in the early modern period. The empirically researched chapters advance existing 'social network theory' into accessible historical discussion.
Antifascism After Hitler
Antifascism After Hitler investigates the antifascist stories, memory sites and youth reception that were critical to the success of political education in East German schools and extracurricular activities. As the German Democratic Republic (GDR) promoted national identity and socialist consciousness, two of the most potent historical narratives to permeate youth education became tales of communist resistors who fought against fascism and the heroic deeds of the Red Army in World War II. These stories and iconic images illustrate the message that was presented to school-age children and adolescents in stages as they advanced through school and participated in the official communist youth or...
Effector-Triggered Immunity
This volume presents a collection of protocols to study effector-triggered immunity (ETI) in both plants and animals from eminent groups in the field. The chapters in this book cover topics such as genetic manipulation of plant and animal pathogens, host cells, and the analysis of key host responses; and techniques used for the analysis of inflammasome activation, cell death pathways, and mitochondria damage in response to pathogens. All of these topics cover a broad spectrum of immunological, biochemical, cell biological, and structural biology approaches to examine ETI. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Effector-Triggered Immunity: Methods and Protocols is a valuable resource for both expert and novice researchers who are interested in learning more about the important and developing field of ETI.
The Terror of the Seas?
This important new book provides the first detailed and clear analysis of the Scots involvement in naval warfare during the early modern period. The lazy use by both contemporaries and some modern authors of the word ‘piracy’ as a catch-all for all sorts of maritime activity obscures a complex picture of Scottish maritime warfare. Through the use of letters of marque and reprisal (rightly distinguished in this analysis) as well as dedicated Crown fleets, Scottish warfare against against a wide range of enemies are scrutinised. This is an impressive book that makes and important contribution to our knowledge of European naval warfare. Its formidably broad range of sources sheds light on many previously little known, or unknown, aspects of naval history. It also provides many valuable new perspectives on the importance of the sea to the Scots, and of the Scots to the naval history of the British Isles.
Creative Industries Switzerland
Policy makers at all levels are discovering the notion of creative industries: the music industry, literature and book market, art market, film and television industries, performing arts, design, architecture, advertising, software / computer games - from economic and innovation strategies to education policy and urban development, the creative industries are being described as a model for success. However, strategies for real, practical implementation remain vague. This publication provides a greatly needed overview of the concepts and specific characteristics of this sector. It analyzes the international discourse, presents up-to-date empirical-statistical Europe-wide analyses, derives models and draws conclusions for the current debate in Switzerland, and places special emphasis on the innovative potential of the creative scene and its dynamics for the entire creative industry.
Never Trust a Russian
Never Trust a Russian is a novel of love, hate, deception and treachery set against the sprawling backdrop of Western Russia. The story begins in Baku on the Caspian Sea and follows three brothers as they flee the ravaging Bolsheviks. They travel with Anarchists, Boatmen and Gypsies across a landscape of turmoil and death. The tale is based upon one family’s journey to America.
