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Fast Facts: Thrombotic Thrombocytopenic Purpura
Thrombotic thrombocytopenic purpura (TTP) is a rare disorder of the blood coagulation system. In most cases, a lack of the ADAMTS13 enzyme leads to an accumulation of ultra-large von Willebrand factor molecules in the plasma which, in turn, initiate the formation of microscopic thromboses in small blood vessels. TTP is a medical emergency. Timely diagnosis and urgent and effective management are vital – mortality in those untreated is in the region of 90%. The understanding of TTP pathogenesis has increased markedly in recent decades. It is now known that TTP is acquired (immunemediated) or congenital, and that the most common type – the acquired form – predominantly affects women in t...
Fast Facts for Patients: Thrombotic Thrombocytopenic Purpura
Thrombotic thrombocytopenic purpura (TTP) is a rare disorder of the blood coagulation system. In most cases, a lack of the ADAMTS13 enzyme leads to an accumulation of ultra-large von Willebrand factor molecules in the plasma which, in turn, initiate the formation of microscopic thromboses in small blood vessels. TTP is a medical emergency. Timely diagnosis and urgent and effective management are vital – mortality in those untreated is in the region of 90%. The understanding of TTP pathogenesis has increased markedly in recent decades. It is now known that TTP is acquired (immunemediated) or congenital, and that the most common type – the acquired form – predominantly affects women in t...
The Coagulation Consult
There have been many changes in the field of coagulation during the past decade. New concepts of epidemiology of risk factors for thrombosis now help clinicians predict who is more likely to form clots after surgery, or after being placed on oral contraceptives. New anticoagulants have the potential to redefine how patients with atrial fibrillation and venous thrombosis are managed. There are new forms of recombinant clotting factors which have changed our approach to hypofibrinogenemia and von Willebrand’s disease. Newer antiplatelet agents are available and their use in patients receiving cardiac stents has mushroomed. The management of thrombosis in the setting of pregnancy has changed ...
Treatment of Acute Leukemias
In Treatment of Acute Leukemias, international experts not only review the state-of-the-art in managing children and adults with acute leukemia, but also debate the pros and cons of current controversial and problematic issues. The book summarizes the best diagnostic and treatment practices for acute leukemias in children, adolescents, and adults. Among the therapies discussed are methotrexate, asparaginase, antipurines, epipodophyllotoxins, hematopoietic stem cell transplantation, hematopoietic growth factors, and immunotherapy.
Internal Medical Care of Cancer Patients
This comprehensive text defines and addresses the broad spectrum of acute and chronic internal medicine disorders that occur in cancer patients and cancer survivors as side effects of the disease itself, or from treatment regimens.
Medical Care of Cancer Patients
Recent therapeutic advances in cancer treatment indicate that cancer is becoming a chronic disease rather than a killer. This comprehensive text is the first to define and address the broad spectrum of acute and chronic internal medicine disorders that occur in cancer patients and cancer survivors as side-effects of the disease itself, or of the treatment regimens. The authors cover nononcologic aspects of internal medicine such as anorexia, obesity, bone loss, diabetes, depression, pain, fatigue, congestive heart failure, skin disorders, and pneumonia. This book is conceived as a companion to standard internal medicine and oncology texts - a comprehensive reference resource for internists caring for cancer patients and oncologists in practice. The text is extensively indexed for easy access and retrieval of information.
Directory of Graduate Research
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.
Roger's Textbook of Pediatric Intensive Care
Long recognized as the leading text in this dynamic field, Rogers’ Textbook of Pediatric Intensive Care provides comprehensive, clear explanations of both the principles underlying pediatric critical care disease and trauma as well as how these principles are applied. Led by Drs. Donald H. Shaffner, John J. McCloskey, Elizabeth A. Hunt, and Robert C. Tasker, along with a team of 27 section editors as well as more than 250 expert global contributors, the fully revised Sixth Edition brings you completely up to date on today’s understanding, treatments, technologies, and outcomes regarding critical illness in children.
The Official ABMS Directory of Board Certified Medical Specialists
The Official ABMS Directory is a database that includes over 600,000 physician profiles, including their board certification status. The current edition allows users to... Research physicians' education, hospital and academic appointments, professional memberships, and certification/recertification status. Find board-certified specialists in any geographic area. Locate qualified healthcare pro-fessionals for a preferred provider plan, and monitor the qualifications of physicians already in the plan. Refer patients with confidence, and keep up to date on career moves and the whereabouts of colleagues.
