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The Emergence of Drugs which Block Calcium Entry
  • Language: en
  • Pages: 163

The Emergence of Drugs which Block Calcium Entry

Calcium Entry Blockers (CEBs) are a new class of drugs which have been pushing back the frontiers of science and medicine for almost two decades. This report reviews some of the wealth of chemical, biological and clinical data describing the discovery and development of these compounds. The scientific importance, therapeutic benefit and marketing potential of these compounds have caused an explosion of scientific literature describing their effects in many preclinical and clinical settings. The definitional characteristics of these compounds suggest a certain predictability of their biological profile but their therapeutic usefulness varies widely dependent upon their physical properties, net hemodynamic effects, duration of action and incidence of side effects. CEBs appear uniquely suited to the treatment of the underlying complexity of cardiovascular disease. The CEBs of the future may live up to the expectations of pathophysiologically based therapeutics and allow the heart and blood vessels to outlive the cells which they support. The development of CEBs is an evolving story of epic proportions and represents the cooperative efforts of individuals in all areas of science.

Congressional Record
  • Language: en
  • Pages: 1344

Congressional Record

  • Categories: Law
  • Type: Book
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  • Published: 1968
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  • Publisher: Unknown

None

Catalog of Copyright Entries. Third Series
  • Language: en
  • Pages: 1602
Pharmacology
  • Language: en
  • Pages: 746

Pharmacology

  • Type: Book
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  • Published: 1993-07
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  • Publisher: Unknown

None

The Engineering Index Annual
  • Language: en
  • Pages: 2264

The Engineering Index Annual

  • Type: Book
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  • Published: 1992
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  • Publisher: Unknown

Since its creation in 1884, Engineering Index has covered virtually every major engineering innovation from around the world. It serves as the historical record of virtually every major engineering innovation of the 20th century. Recent content is a vital resource for current awareness, new production information, technological forecasting and competitive intelligence. The world?s most comprehensive interdisciplinary engineering database, Engineering Index contains over 10.7 million records. Each year, over 500,000 new abstracts are added from over 5,000 scholarly journals, trade magazines, and conference proceedings. Coverage spans over 175 engineering disciplines from over 80 countries. Updated weekly.

IBZ
  • Language: en
  • Pages: 1288

IBZ

  • Type: Book
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  • Published: 1981
  • -
  • Publisher: Unknown

None

Journal of Cardiovascular Pharmacology
  • Language: en
  • Pages: 740

Journal of Cardiovascular Pharmacology

  • Type: Book
  • -
  • Published: 1982
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  • Publisher: Unknown

None

Federation Proceedings
  • Language: en
  • Pages: 1690

Federation Proceedings

  • Type: Book
  • -
  • Published: 1983
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  • Publisher: Unknown

None

The Annals of Thoracic Surgery
  • Language: en
  • Pages: 1162

The Annals of Thoracic Surgery

  • Type: Book
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  • Published: 1994-04
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  • Publisher: Unknown

None

The Horseplayer's Guide to Picking Winners
  • Language: en
  • Pages: 164

The Horseplayer's Guide to Picking Winners

  • Type: Book
  • -
  • Published: 1977
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  • Publisher: Unknown

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