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Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are just as important but have been largely ignored in other works. Aimed at medical professionals and pharmaceutical specialists, this book integrates extracellular and intracellular signalling processes and offers a fresh perspective on new drug targets.
Is your firm’s board creating value—or destroying it? Change is coming. Leadership at the top is being redefined as boards take a more active role in decisions that once belonged solely to the CEO. But for all the advantages of increased board engagement, it can create debilitating questions of authority and dangerous meddling in day-to-day operations. Directors need a new road map—for when to lead, when to partner, and when to stay out of the way. Boardroom veterans Ram Charan, Dennis Carey, and Michael Useem advocate this new governance model—a sharp departure from what has been demanded by governance activists, raters, and regulators—and reveal the emerging practices that are de...
This book provides an in-depth comparative analysis of inequality and the stratification of the digital sphere. Grounded in classical sociological theories of inequality, as well as empirical evidence, this book defines ‘the digital divide’ as the unequal access and utility of internet communications technologies and explores how it has the potential to replicate existing social inequalities, as well as create new forms of stratification. The Digital Divide examines how various demographic and socio-economic factors including income, education, age and gender, as well as infrastructure, products and services affect how the internet is used and accessed. Comprised of six parts, the first ...
This publication examines how opening sequences in films, classic and contemporary, act as hooks to draw the viewer into the film, showing frame by frame how graphics, type and animation are used to create atmosphere, set tone, and lend impact to movies. From Hitchcock and Godard to Tarantino, Luc Besson, and Tim Burton, this large format coffee table book finally illuminates this critical role designers play in filmmaking and gives credit to those that often go uncredited.
This book provides a roadmap for early-career scholars who seek to produce quality research that has a significant impact, within their chosen field and beyond.
In the world of Facebook, Twitter and Yelp, water-cooler conversations with co-workers and backyard small talk with neighbors have moved from the physical world to the digital arena. In this new landscape, organizations ranging from Fortune 500 companies to government agencies to political campaigns continuously monitor online opinions in an effort to guide their actions. Are consumers satisfied with our product? How are our policies perceived? Do voters agree with our platform? Measuring online opinion is more complex than just reading a few posted reviews. Social media is replete with noise and chatter that can contaminate monitoring efforts. By knowing what shapes online opinions, organizations can better uncover the valuable insights hidden in the social media chatter and better inform strategy. This book can help anyone facing the challenge of making sense of social media data to move beyond the current practice of social media monitoring to a more comprehensive use of social media intelligence.
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This book presents the first ever comprehensive overview of national laws recognising sign languages, the impacts they have and the advocacy campaigns which led to their creation. It comprises 18 studies from communities across Europe, the US, South America, Asia and New Zealand. They set sign language legislation within the national context of language policies in each country and show patterns of intersection between language ideologies, public policy and deaf communities’ discourses. The chapters are grounded in a collaborative writing approach between deaf and hearing scholars and activists involved in legislative campaigns. Each one describes a deaf community’s expectations and hopes for legal recognition and the type of sign language legislation achieved. The chapters also discuss the strategies used in achieving the passage of the legislation, as well as an account of barriers confronted and surmounted (or not) in the legislative process. The book will be of interest to language activists in the fields of sign language and other minority languages, policymakers and researchers in deaf studies, sign linguistics, sociolinguistics, human rights law and applied linguistics.
This historic book may have numerous typos and missing text. Purchasers can usually download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1883 edition. Excerpt: ... total amount expended up to that time being " 176, 6, 7i, {not including clothing, &c, received from home." * * *) He was graduated in the class of 1767, his diploma in Latin being dated "Nassau Hall on the day before the Callends of October, 1767," and signed by the Rev. William Tennent, pres.; Elihu Spinner, John Blair, John S. Brainerd, Johannes McQus, Richardus Treat, and Carolus Macknight. This diploma was, in 1875, in the hands of Dr. Otho Evans, of Franklin, War...