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Handbook of Tuberculosis
This second of the three-volume tuberculosis book series provides a comprehensive overview of immunological and cell biological aspects of tuberculosis. Edited by the undisputed world leader in the field, this is the most comprehensive book on the topic available, and the first in recent years to focus on both basic research and clinical aspects of TB.
Handbook of Tuberculosis
Coinciding with the first TB therapies to enter clinical trials in 60 years, this is the most comprehensive account of the latest developments in clinical, therapeutic and basic research into the disease, presented by the most prolific of all researchers in the field. Divided into three clearly structured volumes, the first deals with molecular biology and biochemistry of the pathogen, including genetics and genomics, as well as drug design. The second volume covers cell biology, immunology and vaccine development, while the third is devoted to epidemiology and clinical approaches, including drug resistance, veterinary aspects and clinical field trials. With one new infection worldwide every second, this is an essential reference for bacteriologists, immunologists, pathologists and pathophysiologists, molecular and cell biologists, as well as those working in the pharmaceutical industry.
Immunology of Infection
Established for almost 30 years, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalized, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research. Immunology of Infection, edited by two of the foremost figures in the field, presents the most appropriate, up-to-date techniques in the detail you require. The layout is structured for ease of reference, and the volume will be essential reading for all researchers working in microbiology, immunology, virology, mycology, and parasitology. The new volu...
The Immune Response to Infection
Examines the mechanisms of both the innate and adaptive immune systems as they relate to infection and disease. • Explores the underlying mechanisms of immunity and the many sequelae of host-pathogen interactions, ranging from the sterile eradication of the invader, to controlled chronic infection, to pathologic corollaries of the host-pathogen crosstalk. • Discusses the pathogenesis of certain autoimmune disorders and cancers that are induced by infectious agents but then become independent of the infection process. • Serves as a resource for immunologists, molecular microbiologists, infectious disease clinicians, researchers, and students.
The Innate Immune Response to Infection
Delivers a state-of-the-art review of the innate immune system, utilizing the most current concepts of cellular and molecular biology. The book focuses on evolutionary aspects, describing the major cells, humoral factors, receptors, and effector responses central to innate immunity and its important relation to acquired immunity. In-depth treatment is given to the performance of the innate immune system in various situations, including bacterial, viral, fungal, and parasitic infection.
Tuberculosis
The authors discuss fundamental questions about the biology, genetics, mechanisms of pathogenicity, mechanisms of resistance, and drug development strategies that are likely to provide important new knowledge about TB and new interventions to prevent and treat this disease.
The Way of the Linguist
The Way of The Linguist, A language learning odyssey. It is now a cliché that the world is a smaller place. We think nothing of jumping on a plane to travel to another country or continent. The most exotic locations are now destinations for mass tourism. Small business people are dealing across frontiers and language barriers like never before. The Internet brings different languages and cultures to our finger-tips. English, the hybrid language of an island at the western extremity of Europe seems to have an unrivalled position as an international medium of communication. But historically periods of cultural and economic domination have never lasted forever. Do we not lose something by rely...
Novel Vaccination Strategies
The protection mode of most available vaccines is based on antibody responses. Since efficient immune responses to many pathogens rely on activating all arms of the immune system, traditional vaccine development does not provide efficient protection against many diseases. Novel vaccination strategies need to allow presentation of antigens that activate the full array of the immune response in the right composition and should prevent pathogen entry by mobilizing the mucosal immune response. New technological advances optimize the immunogenicity of 'live' and sub-unit vaccines. This book offers an interdisciplinary overview on research and future strategies for rational vaccine design based on recent developments in molecular biology and immunology. It covers new aspects of the immunological interplay between prokaryotic and eukaryotic systems as well as achievements in the development of novel vaccine candidates. Chapters on edible vaccines, on vaccines against bioterror agents and on economical and safety aspects of novel vaccine development round off this title.
Heuristic Search
Search has been vital to artificial intelligence from the very beginning as a core technique in problem solving. The authors present a thorough overview of heuristic search with a balance of discussion between theoretical analysis and efficient implementation and application to real-world problems. Current developments in search such as pattern databases and search with efficient use of external memory and parallel processing units on main boards and graphics cards are detailed. Heuristic search as a problem solving tool is demonstrated in applications for puzzle solving, game playing, constraint satisfaction and machine learning. While no previous familiarity with heuristic search is necessary the reader should have a basic knowledge of algorithms, data structures, and calculus. Real-world case studies and chapter ending exercises help to create a full and realized picture of how search fits into the world of artificial intelligence and the one around us. - Provides real-world success stories and case studies for heuristic search algorithms - Includes many AI developments not yet covered in textbooks such as pattern databases, symbolic search, and parallel processing units
Exploring Immunology
Knapp und präzise erklärt dieses einführende Lehrbuch der Immunologie die Funktion des Immunsystems anhand sorgfältig ausgewählter Beispiele aus der klinischen Praxis und dem Experiment. Von Büchern mit ähnlichem Themenspektrum unterscheidet es sich durch den klar evidenzbasierten Ansatz. Die Autoren -- ein erfahrener Dozent und ein angesehener Forscher -- regen dabei stets zur kritischen Reflexion des gelernten Stoffs an. Based on examples using clinical and experimental data, this concise introductory textbook provides an insight into the immune system, prompting readers to ask critical questions in order to further advance our understanding. Website: www.wiley-vch.de/home/immunology
