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Surgery in the Multimodal Management of Gastric Cancer
Although there has been a slow but steady decrease in incidence, gastric cancer remains the second leading cause of cancer death worldwide. Several aspects of the oncological and surgical management are still controversial and so gastric cancer represents a challenge for the surgeon. This book aims to delineate the state of the art in the surgical and oncological treatment of gastric cancer, describing the new TNM staging system, the extent of visceral resection and lymphadenectomy focusing on the different open and minimally invasive surgical techniques and discussing intraoperative chemohyperthermia and neoadjuvant and adjuvant treatment. Operative endoscopy and endoscopic ultrasonography are also discussed, as these now have an important role in both diagnostic work-up and palliative care of gastric cancer patients. Only a multidisciplinary approach involving the surgeon, gastroenterologist, and oncologist can produce the comprehensive and integrated overview that today constitutes a winning strategy for the optimization of results.What we hope we have achieved is a flexible, up-to-date, exhaustive publication, rich in illustrations and consistent with evidence-based medicine.
Surgical Treatment of Pancreatic Diseases
Pancreatic diseases are a crucial issue not only because of their epidemiological significance, and their anatomical and metabolic complexity, but also because of the different treatment options available and their implications for surgery. Due to the slow but steady increase in the incidence of pancreatitis and pancreatic cancer, these diseases are today a real challenge for the surgeon. This volume presents the state of the art of surgery in the treatment of inflammatory and neoplastic pancreatic diseases, describing in detail the different approaches and their most relevant technical aspects. Also described are conventional and interventional radiology, operative endoscopy and endoscopic ultrasonography (which has recently acquired a diagnostic role), and adjuvant and neoadjuvant therapy for treatment or palliation: for only a multidisciplinary approach can produce a global vision, a winning strategy for the optimization of results. Along with the texts, all written by experts, the volume includes color images and drawings. It will prove itself a very useful tool in clinical practice.
Gastric Cancer: the 25-year R-Evolution
Twenty-five years ago, a monograph on gastric cancer was published by the Italian Society of Surgery: that book is recognized as a milestone in the management of these tumors in Italy. Oncological and surgical knowledge in the field of gastric cancer have changed dramatically over the last 25 years. The aim of this book is to offer an essential update on current diagnostic approaches and optimal treatment strategies. It gives comprehensive information on gastric cancer not neglecting the basic sciences, which can shed light on the carcinogenesis mechanisms involved in this pathology. The principles of tailored and multimodal treatment are examined according to the latest guidelines with the ...
Lung Cancer
This work, Lung Cancer, Volume 2: Diagnostic and Therapeutic Methods and Reviews, in the Methods in Molecular Medicine series presents an overview of the current status of those methods useful in the diagnosis and tre- ment of lung cancer—both as it exists in the clinic and as it is being revoluti- ized in the laboratory. The book is intended to serve as a resource for researchers wishing to increase their knowledge of current and cutting edge technologies, in order that their investigations into neoplasms of the lung may benefit from this enriched diversity of techniques and approaches. Owing to the complex nature of the disease and the variety of methods available to analyze and attack it, no volume attempting to define diagnostic and therapeutic approaches to lung cancer can ever be complete. The sheer number of investigators involved in lung cancer research guarantees that some aspect will be inadvertently excluded. However, I hope that the range of techniques included herein will serve to open up new avenues of investigation for both the novice and experienced researcher.
Encyclopedia of Molecular Mechanisms of Disease
This comprehensive encyclopedia supplies the reader with concise information on the molecular pathophysiology of disease. Entries include defined diseases (such as Parkinson's disease) as well as pathophysiological entities (such as tremor). The 1,200 essays are brilliantly structured to allow rapid retrieval of the desired information. For more detailed reading, each entry is followed by up to five references. Individual entries are written by leading experts in the respective area of research to ensure state-of-the-art descriptions of the mechanisms involved. It is an invaluable companion for clinicians and scientists in all medical disciplines.
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Io con la morte
In queste pagine si respirano tutta la sofferenza e il dolore dell’Autore che ci racconta la sua personale e intima esperienza di vita: dalla scoperta di avere un cancro a tutto il percorso che ha compiuto, con l’assistenza fondamentale della famiglia e dei tanti medici e operatori sanitari incontrati. Ma non si tratta solo di parole che ci raccontano dei momenti più bui e difficili. Nel buio infatti si fa avanti una luce, prima piccola e flebile, poi sempre più luminosa. L’idea che ci accompagna della morte trova forma e personificazione nei momenti più difficili della vita, quando tutto sembra oramai perduto per sempre. Ma è allora che c’è una parola a cui dobbiamo aggrapparci...
La Medicina Oncologica : Diagnosi, Terapia e gestione clinica
Dopo diverse edizione del volume di Gianni Bonadonna, la casa editrice EDRA ha rilevato il catalogo della Masson ed ha voluto realizzare un nuovo testo per rendere conto degli enormi cambiamenti in oncologia medica con la rapida e costante evoluzione delle terapie oncologiche. In questi ultimi anni si è passati infatti dalla progressione lineare tra ricerca di base, sperimentazione e pratica clinica all’affermarsi di un nuovo modello di “flusso circolare”. Questo ha significato la possibilità di rispondere con farmaci mirati alle specifiche caratteristiche metaboliche, istologiche o molecolari del tumore. Nella trattazione di ciascuna neoplasia l’obiettivo degli autori era far emergere questo nuovo rapporto tra i dati di laboratorio e l’assistenza al letto del malato Il testo vuole essere un punto di riferimento per l’attività professionale quotidiana dell’oncologo clinico nel suo complesso ma sarà sicuramente uno strumento di formazione importante per lo specializzando.
