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Now in its thoroughly updated Third Edition, the Hypertension Primer is a comprehensive, readable source of state-of-the-art scientific and clinical information on hypertension. The book contains more than 150 short chapters by distinguished experts that cover every aspect of hypertension and its pathogenesis, epidemiology, impact, and management. The chapters are grouped into three well-organized sections--basic science, population science, and clinical management--and each chapter is cross-referenced to other relevant chapters. Each chapter is easily digestible and begins with a bulleted list of key points.
Brody's Human Pharmacology is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both basic and clinical perspectives. What can be a very difficult and complex topic is divided into easily digestible chapters, each of which is clearly structured from a therapeutic overview to mechanisms of action, relationships to clinical responses, pharmacokinetics, pharmacovigilance, new developments, and clinical relevance for all health professionals. - Contains all the essential aspects of pharmacology – suitable for exam preparation - Full color illustrations explain important processes and color-coded boxe...
This reference is a volume in the Handbook of Physiology, co-published with The American Physiological Society. Growth in knowledge about the microcirculation has been explosive with the field becoming fragmented into numerous subdisciplines and subspecialties. This volume pulls all of the critical information into one volume. - Meticulously edited and reviewed. Benefit: Provides investigators a unique tool to explore the significance of their findings in the context of other aspects of the microcirculation. In this way, the updated edition has a direct role in helping to develop new pathways of research and scholarship - Highlights the explosive growth in knowledge about the microcirculation including the biology of nitric oxide synthase (NOS), endothelial cell signaling, angiogenesis, cell adhesion molecules, lymphocyte trafficking, ion channels and receptors, and propagated vasomotor responses. Benefit: Microcirculatory biology has become fragmented into numerous sub-disciplines and subspecialties, and these reference reintegrates the information in one volume
BEST: Implementing Career Development Activities for Biomedical Research Trainees provides an instructional guide for institutions wanting to create, supplement or improve their career and professional development offerings. Each chapter provides an exclusive perspective from an administrator from the 17 Broadening Experiences in Scientific Training (BEST) institutions. The book can aid institutions who train graduate students in a variety of careers by teaching faculty and staff how to create and implement career development programming, how to highlight the effectiveness of offerings, how to demonstrate that creating a program from scratch is doable, and how to inform faculty and staff on getting institutional buy-in. This is a must-have for graduate school deans and faculty and staff who want to implement and institutionalize career development programing at their institutions. It is also ideal for graduate students and postdocs.
Key workers in vascular medicine and biology apply state-of-the-art techniques in cell and molecular biology to study the endothelial and vascular smooth muscle cells. The distinguished scientists and clinicians open a new area of endocrinology, which sees the vasculature and kidney as endocrine organs and sheds new light on the hormonal regulation of the cardiovascular system. They also add significantly to our current understanding of the autocrine, paracrine, and endocrine regulation of vascular function in health and in those vascular disease states that accompany diabetes mellitus, dyslipidemia, and hypertension. Endocrinology of the Vasculature is the first book to comprehensively and systematically explore the vasculature as an endocrine organ.
"A grand debut novel full of characters who come into a reader's mind and heart and never leave. Stephanie Powell Watts is a writer of wondrous skill, imagination, and sensitivity, and No One Is Coming to Save Us is a beautiful testament to that." Edward P. Jones, author of The Known World JJ Ferguson has returned home to Pinewood, North Carolina, to build his dream house and to pursue his high school sweetheart, Ava. But as he re-enters his former world, where factories are in decline and the legacy of Jim Crow is still felt, he’s startled to find that the people he once knew and loved have changed just as much as he has. Ava is now married and desperate for a baby, though she can’t see...
The discovery and development of a biological active molecule with therapeutic properties is an ever increasing complex task, highly unpredictable at the early stages and marked, in the end, by high rates of failure. As a consequence, the overall process leading to the production of a successful drug is very costly. The improvement of the net outcome in drug discovery and development would require, amongst other important factors, a good understanding of the molecular events that characterize the disease or pathology in order to better identify likely targets of interest, to optimize the interaction of an active agent (small molecule or macromolecule of natural or synthetic origin) with thos...
There is growing interest in understanding the dynamic roles of physical forces in vascular development, homeostasis, and disease. While it is well established that all cells are responsive to their external environment, and the cells of the vascular system are constantly exposed to hemodynamic forces, we are still uncovering how these external cues influence vascular cell signaling to direct cell identity, cell phenotype, vascular organization, and vessel function. Work is emerging that defines how vascular cells interpret and respond to these external forces to reveal how the biomechanical environment influences cell signaling and behavior. This collection on vascular mechanotransduction will address how cells respond to external physical forces during vessel development and organization, later in vessel homeostasis, and in the context of cardiovascular disease.