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Neurotransmission is a multicomponent process. Transmitters, released by neuronal activity, act on pre- and postsynaptic receptors, and many books detail advances in the receptor field. In addition, after their release from nerve endings, transmitters are removed from the neuronal vicinity by uptake into neuronal or glial cells by specific tra- porter proteins that have been studied intensely over the last 30 years; this information is scattered throughout numerous publishing vehicles. Therefore, the primary aim of this second edition of N- rotransmitter Transporters: Structure, Function, and Regulation is to offer a comprehensive picture of the characterization of neurotransmitter transport...
Movement Disorder Emergencies: Diagnosis and Treatment provides a fresh and unique approach to what is already a high-profile subspecialty area in clinical neurology. The disorders covered in this volume are standard fare in the field but emphasize the urgencies and emergencies that can occur. One of the very attractive features of the field of movement disorders is that diagnosis is often based on unique visible and sometimes audible phenomenological symptoms and signs. Therefore, in this era of highly sophisticated laboratory and radiological diagnostic tools, the diagnosis of many movement disorders is still largely made in the clinic where pattern recognition is key. Crucial to astute cl...
Inflammation has invaded the field of psychiatry. The finding that cytokines are elevated in various affective and psychotic disorders brings to the forefront the necessity of identifying the precise research domain criteria (RDoCs) that inflammation is responsible for. This task is certainly the most advanced in major depressive disorders. The reason is that a dearth of clinical and preclinical studies has demonstrated that inflammation can cause symptoms of depression and conversely, cytokine antagonists can attenuate symptoms of depression in medical and psychiatric patients with chronic low grade inflammation. Important knowledge has been gained on the symptom dimensions that inflammation is driving and the mechanisms of action of cytokines in the brain, providing new targets for drug research and development. The aim of the book “Inflammation-Associated Depression” is to present this field of research and its implications in a didactic and comprehensive manner to basic and clinical scientists, psychiatrists, physicians, and students at the graduate level.
(Screen World). The 2006 edition of Screen World highlights the surprise Academy Award-winner for Best Picture, Crash, featuring Matt Dillon, Terrence Howard, and Sandra Bullock, which also won Academy Awards for Best Original Screenplay and Best Film Editing; the groundbreaking gay love story Brokeback Mountain, winner of three Academy Awards, with Oscar-nominated performances by Heath Ledger and Jake Gyllenhaal; the Johnny Cash biopic Walk the Line, which earned a Best Actress Academy Award for Reese Witherspoon and a Best Actor nomination for Joaquin Phoenix; Philip Seymour Hoffman's uncanny, Oscar-winning Best Actor impersonation of Truman Capote in Capote; Best Supporting Actress winner...
Now in its Third Edition, this comprehensive, problem-based textbook discusses the full range of complications in anesthesiology. Major sections cover intraoperative and postoperative complications affecting each organ system-respiratory, cardiovascular, neurologic, ophthalmologic, renal, hematologic and hemostatic, gastrointestinal, endocrine, obstetric, immunologic and infectious, and disorders of temperature regulation. Coverage includes problems that are rarely mentioned in older textbooks, such as ischemic optic neuropathy and postoperative cognitive dysfunction. Chapters address complications associated with specific equipment and techniques, with adverse drug interactions, and with herbal remedies and over-the-counter medications. Also included are chapters on medicolegal issues and risks to the anesthesiologist.
Orofacial Pain: A Guide to Medications and Management brings together guidance and information on the rational use of medications for the treatment of chronic orofacial pain. Focusing on clinically relevant information throughout and aiming itself squarely at the needs of dentists and other clinicians working directly with orofacial pain, the book covers the use of oral, injectable and topical medications for managing neuropathic and musculoskeletal pain, headache, and uncommon orofacial pain disorders. Useful features, such as discussion of the top 60 medications prescribed for orofacial pain, are integrated with comprehensive coverage of drug types, pharmacolegal issues, and the interaction of medication management with other treatment strategies.
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