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Endolysosomal Voltage-Dependent Cation Channels
This book covers the molecular structures and the cellular and in vivo function of endosomes and lysosomes, i.e. intracellular vesicles which are involved in many cellular processes such as endocytosis, intracellular trafficking, degradation of material from inside (e.g. autophagy) and outside the cell as well as exocytosis. Membranes of endolysosomal organelles contain an amazing number and diversity of ion channels. These ion channels are the topic of the present book that focusses on describing the structure, the biophysical properties, physiological functions of endolysosomal ion channels at the molecular, cellular and in vivo level.
TRP Channels in Health and Disease
Almost 25 years ago, the first mammalian transient receptor potential (TRP) channel was cloned and published. TRP channels now represent an extended family of 28 members fulfilling multiple roles in the living organism. Identified functions include control of body temperature, transmitter release, mineral homeostasis, chemical sensing, and survival mechanisms in a challenging environment. The TRP channel superfamily covers six families: TRPC with C for “canonical”, TRPA with A for “ankyrin”, TRPM with M for “melastatin”, TRPML with ML for “mucolipidin”, TRPP with P for “polycystin”, and TRPV with V for “vanilloid”. Over the last few years, new findings on TRP channels have confirmed their exceptional function as cellular sensors and effectors. This Special Book features a collection of 8 reviews and 7 original articles published in “Cells” summarizing the current state-of-the-art on TRP channel research, with a main focus on TRP channel activation, their physiological and pathophysiological function, and their roles as pharmacological targets for future therapeutic options.
Toxic Injustice
The pesticide dibromochloropropane, known as DBCP, was developed by the chemical companies Dow and Shell in the 1950s to target wormlike, soil-dwelling creatures called nematodes. Despite signs that the chemical was dangerous, it was widely used in U.S. agriculture and on Chiquita and Dole banana plantations in Central America. In the late 1970s, DBCP was linked to male sterility, but an uneven regulatory process left many workers—especially on Dole’s banana farms—exposed for years after health risks were known. Susanna Rankin Bohme tells an intriguing, multilayered history that spans fifty years, highlighting the transnational reach of corporations and social justice movements. Toxic Injustice links health inequalities and worker struggles as it charts how people excluded from workplace and legal protections have found ways to challenge power structures and seek justice from states and transnational corporations alike.
Grazer Morgenpost
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Hemodialysis Access
This comprehensive reference on the fundamentals of hemodialysis access creation and advanced management for maintenance is designed to meet the needs of all surgeons and physicians responsible for the treatment and care of patients undergoing dialysis. The book opens by discussing every aspect of dialysis access planning, including selection of the right access for the individual patient and access strategies. Hemodialysis access techniques, from the most basic to the most complex and unconventional, are then described step by step, and guidance is provided on follow-up. Detailed attention is also devoted to the challenging management of specific complications of dialysis access surgery, including failing hemodialysis access. The book includes a wealth of informative, high-quality images and illustrations, and the authors are prominent vascular surgeons, transplant surgeons, general surgeons, nephrologists, and interventional radiologists from across the United States.
Troubling American Women
American women have lived in Hong Kong, and in neighboring Macao, for nearly two centuries. Many were changed by their encounter with Chinese life and British colonialism. Their openness to new experiences set them apart, while their "pedagogical impulse" gave them a reputation for outspokenness that troubled others. Drawing on memoirs, diaries, newspapers, films, and other texts, Stacilee Ford tells the stories of several American women and explores how, through dramatically changing times, they communicated their notions of national identity and gender.Troubling American Womenis a lively and provocative study of cross-cultural encounters between the Hong Kong and the US and use of stereotypes of American womanhood in Hong Kong popular culture. Stacilee Fordhas lived in Hong Kong for 18 years. She teaches history and American studies at the University of Hong Kong.
New York Magazine
New York magazine was born in 1968 after a run as an insert of the New York Herald Tribune and quickly made a place for itself as the trusted resource for readers across the country. With award-winning writing and photography covering everything from politics and food to theater and fashion, the magazine's consistent mission has been to reflect back to its audience the energy and excitement of the city itself, while celebrating New York as both a place and an idea.
New York Magazine
New York magazine was born in 1968 after a run as an insert of the New York Herald Tribune and quickly made a place for itself as the trusted resource for readers across the country. With award-winning writing and photography covering everything from politics and food to theater and fashion, the magazine's consistent mission has been to reflect back to its audience the energy and excitement of the city itself, while celebrating New York as both a place and an idea.
