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Molecular Basis and Emerging Strategies for Anti-aging Interventions
This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging interventions, while also discussing the discovery of targets for geroprotective drugs. Although significant medical advances in the treatment and eradication of life-threatening conditions such as cardiovascular and infectious disease have been made over the past five decades, the prevalence of age-related disorders still remains high in older populations. Intervening into aging is the next frontier in contemporary medicine, and will be of increasing importance over time, as other sources of poor health are combated more and more successfully. Given the universal interest in anti-aging strategies, the book will appeal to a very broad audience. It addresses a diverse range of anti-aging interventions – including stem cells, autophagy, senolytics, anti-inflammatory methods, and telomerase induction – that will be of interest to scientists and researchers from various disciplines in the life sciences.
Emerging Anti-Aging Strategies
The book focuses on the emerging anti-aging approaches for maintaining better health in old age. It provides a current understanding of the underlying principle, possible targets, implementation approaches, and efficacy of the various anti-aging strategies. The chapters include a wide range of topics incorporating the major advances in anti-aging strategies, including telomerase activation, stem cell therapy, autophagy induction, sirtuin activation, and dietary restrictions. Further, it discusses the epigenetic mechanisms underlying aging-related processes and epigenetic strategies to delay and reverse aging-related diseases. The book covers the strategy based on tissue engineering and regenerative medicine for understanding the complexity of aging and restoring the functionalities of organ systems. It further presents the applications of melatonin supplementation-based anti-aging therapeutic intervention. Finally, the book reviews the ethical dimension of anti-aging intervention strategies. This book is immensely useful to scientists and researchers from various disciplines in the life sciences.
Nutraceutical and Functional Foods in Disease Prevention
Current research on health, nutrition, and preventative care will always be in demand. As the battles against ailments such as diabetes and heart disease continue, medical professionals are seeking to create a healthier society through nutrition and dietary-based tactics. Nutraceutical and Functional Foods in Disease Prevention is a comprehensive publication providing current research on the dynamic fields of pharmaceutical and biomedical science in relation to nutrition. This book examines the interactions and associations between nutritive value and its therapeutic applications in human health. Touching on topics such as the impact of probiotics in human health and disease treatment, recent trends in functional foods for obesity management, and the clinical role of antioxidants in the treatment of diseases, this title proves a valuable resource for academicians, healthcare practitioners, medical researchers, and higher education students preparing for careers as health professionals.
Oxidative Stress in Vertebrates and Invertebrates
This volume presents a unique comparative treatment of the role oxidative stress plays in vertebrates and invertebrates in multiple organ systems with regards to cell death, development, aging, and human diseases, and anti-oxidant therapy. It offers comprehensive reviews of the current understanding of oxidative stress-mediated physiology and pathology as well as directions for future research. It also provides current information on the role of oxidative stress in neurodegenerative diseases, cardiovascular diseases, and various types of cancer mediated by oxidative stress.
Artificial Intelligence for Healthy Longevity
This book reviews the state-of-the-art efforts to apply machine learning and AI methods for healthy aging and longevity research, diagnosis, and therapy development. The book examines the methods of machine learning and their application in the analysis of big medical data, medical images, the creation of algorithms for assessing biological age, and effectiveness of geroprotective medications. The promises and challenges of using AI to help achieve healthy longevity for the population are manifold. This volume, written by world-leading experts working at the intersection of AI and aging, provides a unique synergy of these two highly prominent fields and aims to create a balanced and comprehensive overview of the application methodology that can help achieve healthy longevity for the population. The book is accessible and valuable for specialists in AI and longevity research, as well as a wide readership, including gerontologists, geriatricians, medical specialists, and students from diverse fields, basic scientists, public and private research entities, and policy makers interested in potential intervention in degenerative aging processes using advanced computational tools.
Sleep and Clocks in Aging and Longevity
This edited volume focuses on the interplay between sleep and circadian rhythms with health, aging and longevity. Sleep is absolutely important for human health and survival, as insufficient sleep is associated with a plethora of conditions, including the poor quality of life, onset of several diseases, and premature death. The sleep–wake cycle is an evolutionary conserved neurobiological phenomenon, and is a prominent manifestation of the biological clocks localised in the suprachiasmatic nucleus (SCN). Understanding bidirectional relationship between sleep and circadian rhythms is of utmost importance and urgency, especially in the context of modern lifestyle where sleep is often out of ...
Wellness Lifestyle Management
Contemporary society is affected by several non-communicable diseases mainly due to increasing inactivity. Hypokinetic diseases like diabetes, hypertension, and other cardiovascular diseases are causing severe strain on the nations. Inactivity not only increases obesity but is also a direct factor for non-communicable diseases. Though exercise seems an effective therapeutic factor that could heavily influence the health status of individuals, physical wellness alone cannot achieve the desired health status for an individual. Other aspects like nutrition and emotional stress also play a vital role in securing proper health fitness and functional health among individuals. Even optimizing and s...
