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CRISPR
The book presents a machine-generated literature review on CRISPR (clustered regularly interspaced short palindromic repeats) from 114 selected papers published by Springer Nature in the last few years, which are then organized by the book editors with a human-written introduction to each chapter. Each chapter presents summaries of predefined themes and provides the reader with a basis for further exploration of the topic. As one of the experimental projects initiated by Springer Nature for AI book content generation, this book shows the latest developments in the CRISPR field. It will be a useful reference for graduate students who are interested in CRISPR-related research and early-career researchers who need an overview of the current development of the field.
Principles and Practice of Gynecologic Oncology
Completely reorganized to be more clinically focused on diagnosis and treatment, Principles and Practice of Gynecologic Oncology, Eighth Edition, provides the up-to-date information practitioners, researchers, and students need in an easily accessible manner. Drs. Dennis S. Chi, Dineo Khabele, Don S. Dizon, and Catheryn Yashar oversee an expert team of international, multidisciplinary authors who offer practical coverage of the entire field, including new management and treatment strategies for gynecologic cancers. Each disease site now has a dedicated section with individual chapters on epidemiology, pathogenesis, prevention, diagnostic imaging, radiation, chemotherapy, targeted therapy, and more—all designed for quick clinical reference and efficient study.
DNA Replication
Updated and revised, this thorough volume covers a range of methods focusing on systems, including mammalian, yeast, bacterial and archaeal. This second edition of DNA Replication: Methods and Protocols describes approaches to analyze whole genomes to single molecules, as well as both in vivo and in vitro experiments. As a volume in the highly successful Methods in Molecular Biology series, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, DNA Replication: Methods and Protocols, Second Edition provides a collections of methods intended for newcomers to this research field and for established laboratories.
R-Loops
This detailed book compiles a series of laboratory protocols covering the most important aspects of R-loop biology. Beginning with a range of methods allowing for the detection of DNA-RNA hybrids, as well as their purification and visualization by electron microscopy, the volume continues with methods based on the use of RNase H-derived tools to detect DNA-RNA hybrids in vitro and in vivo. Several protocols permit studying non-canonical RNA nucleotides in the R-loop context, as well as a number of specific protocols devoted to the investigation of R-loop topology and their functional roles in the biology of mitochondria and telomeres. Finally, a large block of chapters is dedicated to differ...
Cézanne to Van Gogh
The fascinating story of Dr. Paul Gachet's collection of works of art by artists such as Cezanne, Van Gogh, and Monet.
Doing Business 2010
The seventh in a series of annual reports investigating the regulations that enhance business activity and those that constrain it, 'Doing Business' presents quantitative indicators on business regulations and the protection of property rights that can be compared across 183 economies--from Afghanistan to Zimbabwe--and over time. Regulations affecting 10 stages of a business's life are measured: starting a business, dealing with construction permits, employing workers, registering property, getting credit, protecting investors, paying taxes, trading across borders, enforcing contracts and closing a business. Data in 'Doing Business 2010' are current as of June 1, 2009. The indicators are used to analyze economic outcomes and identify what reforms have worked, where and why.
A Chaotic Hierarchy
This collection of articles introduces the idea of a hierarchical order in chaotic systems and natural phenomena. To understand nature, nonlinear sciences use a multidisciplinary perspective. Therefore the book integrates research work of different fields: experimental evidence for the theory drawn from physics, biology and chemistry; theoretical progress in mathematical treatment, numerical techniques and graphical methods of nonlinear sciences; and to not-yet-understood philosophical and fundamental problems related to chaos and cosmos, chaos and quantum mechanics or evolutionary dynamics. Featuring the most recent advances in nonlinear dynamics this collection should provide an indispensable reference source and starting point for further research concerning dynamical and hierarchical chaotic systems. Besides this book is in honor of Professor O E Rössler, one of the pioneers of Chaos Theory, who celebrated his 50th birthday in May 1990.
