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Molecular mechanisms and physiology of disease
In a simplified form, epigenetics refers to heritable changes in phenotype that are not due to changes in the underlying DNA sequence. In this book, epigenetic mechanisms of regulation and dysregulation in health and disease are explored in great depth. Detailed chapters on epigenetic processes including DNA methylation and chromatin post-translational modifications including potential interventions with DNA methyltransferase inhibitors and histone deacetylase inhibitors are explored in initial chapters. These provide a detailed overview and important background to the entire field. The book is then focussed on epigenetic mechanisms involved in various diseases including anti-inflammatory an...
Decolonising Criminology
This book undertakes an exploratory exercise in decolonizing criminology through engaging postcolonial and postdisciplinary perspectives and methodologies. Through its historical and political analysis and place-based case studies, it challenges criminological inquiry by installing colonial structures of power at the centre of the contemporary criminological debate. This work unseats the Western nation-state as the singular point of departure for comparative criminological and socio-legal research. Decolonising Criminology argues that postcolonial and postdisciplinary critique can open up new pathways for criminological investigation. It builds on recent debates in criminology from outside of the Anglosphere. The authors deploy a number of heuristic devices, perspectives and theories generally ignored by criminologists of the Global North and engage perspectives concerned with articulating new decolonised epistemologies of the Global South. This book disputes the view that colonisation is a thing of the past and provides lessons for the Global North.
History of Allergy
The prevalence of allergic diseases has increased dramatically over recent decades, both in terms of the number of sufferers and the number of allergies. This is a trend that has frequently been referred to as 'the epidemic of the 21st century'. As described in ancient texts, allergies have been known for over 2,000 years, but the term 'allergy' was only coined at the beginning of the 20th century when doctors began to understand their pathophysiological basis. This book presents a detailed and varied historical overview of the field of allergology. Beginning with insights on allergy from antiquity to the 20th century and the development of the associated terminology, it compiles historical ...
The Routledge International Handbook on Decolonizing Justice
The Routledge International Handbook on Decolonizing Justice focuses on the growing worldwide movement aimed at decolonizing state policies and practices, and various disciplinary knowledges including criminology, social work and law. The collection of original chapters brings together cutting-edge, politically engaged work from a diverse group of writers who take as a starting point an analysis founded in a decolonizing, decolonial and/or Indigenous standpoint. Centering the perspectives of Black, First Nations and other racialized and minoritized peoples, the book makes an internationally significant contribution to the literature. The chapters include analyses of specific decolonization p...
Atopic Dermatitis
This book presents the state of the art in research into atopic dermatitis, or atopic eczema, and provides numerous effective practical management recommendations that are grounded in the immense clinical experience of the author. A scientific evidence-based approach to the subject is adopted, progressing from clinical symptoms in different disease stages, molecular genetics, and pathophysiology through to treatment and prevention. All aspects of patient management are covered, including diagnostics, avoidance strategies, emollient therapy, and acute treatment of eczema and itch. Diverse special therapeutic approaches are discussed, ranging from glucocorticoids, topical calcineurin inhibitor...
Lipids in Health and Nutrition
The wide coverage of the apparently dual nature of lipids provides the latest information for graduates and researchers in the food science and nutrition areas.
Advances in High Temperature Ceramic Matrix Composites and Materials for Sustainable Development
Global population growth and tremendous economic development has brought us to the crossroads of long-term sustainability and risk of irreversible changes in the ecosystem. Energy efficient and ecofriendly technologies and systems are critically needed for further growth and sustainable development. While ceramic matrix composites were originally developed to overcome problems associated with the brittle nature of monolithic ceramics, today the composites can be tailored for customized purposes and offer energy efficient and ecofriendly applications, including aerospace, ground transportation, and power generation systems. The 9th International Conference on High Temperature Ceramic Matrix C...
