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Issues in Biophysics and Geophysics Research and Application: 2012 Edition
Issues in Biophysics and Geophysics Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biophysics. The editors have built Issues in Biophysics and Geophysics Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biophysics in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biophysics and Geophysics Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Geography in America at the Dawn of the 21st Century
Geography in America at the Dawn of the 21st Century surveys American geographers' current research in their specialty areas and tracks trends and innovations in the many subfields of geography. As such, it is both a 'state of the discipline' assessment and a topical reference. It includes an introduction by the editors and 47 chapters, each on a specific specialty. The authors of each chapter were chosen by their specialty group of the American Association of Geographers (AAG). Based on a process of review and revision, the chapters in this volume have become truly representative of the recent scholarship of American geographers. While it focuses on work since 1990, it additionally includes related prior work and work by non-American geographers. The initial Geography in America was published in 1989 and has become a benchmark reference of American geographical research during the 1980s. This latest volume is completely new and features a preface written by the eminent geographer, Gilbert White.
Rifting and Sediments in the Red Sea and Arabian Gulf Regions
Rifting and Sediments in the Red Sea and Arabian Gulf Regions is a unique text that covers a wide range of topics related to the tectonics and geology of the Red Sea and Arabian (Persian) Gulf region. This book is a collection of invited and peer-reviewed chapters contributed by active researchers around the world. The topics covered in this book include tectonics, magmatism, and lithology, particularly in the Red Sea area. The book also delves into the sediments and evaporites of the Red Sea and Gulf. As the area around the Arabian Peninsula is prone to earthquakes, the seismic hazard estimated in the Red Sea region is also covered by several chapters. Each chapter presents new data and offers extensive lists of references for the reader to explore further. With the ongoing debates regarding the structure of the Red Sea, this book serves as an excellent resource for researchers and any individuals interested in the geology of these two unique seas.
Human and Animal Relationships
Mycology, the study of fungi, originated as a subdiscipline of botany and was a descriptive discipline, largely neglected as an experimental science until the early years of this century. A seminal paper by Blakeslee in 1904 provided evidence for self-incompatibility, termed "heterothallism", and stimulated interest in studies related to the control of sexual reproduction in fungi by mating-type specificities. Soon to follow was the demonstration that sexually reproducing fungi exhibit Mendelian inheritance and that it was possible to conduct formal genetic analysis with fungi. The names Burgeff, Kniep and Lindegren are all associated with this early period of fungal genetics research. These...
A Comprehensive Guide to Toxicology in Preclinical Drug Development
A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. The book discusses discovery toxicology and the international guidelines for safety evaluation,...
Microarrays
Microarray Technology, Volumes 1 and 2, present information in designing and fabricating arrays and binding studies with biological analytes while providing the reader with a broad description of microarray technology tools and their potential applications. The first volume deals with methods and protocols for the preparation of microarrays. The second volume details applications and data analysis, which is important in analyzing the enormous data coming out of microarray experiments. Among the topics discussed in Volume 1: Synthesis Methods, are matrices in the synthesis of microarrays, array optimization processes, array-based comparative genomic hybridization, 60-mer oligonucleotide probe...
Benefit-Risk Assessment in Pharmaceutical Research and Development
Many practitioners in the pharmaceutical industry are still largely unfamiliar with benefit-risk assessment, despite its growing prominence in drug development and commercialization. Helping to alleviate this knowledge gap, Benefit-Risk Assessment in Pharmaceutical Research and Development provides a succinct overview of the key considerations relevant to benefit-risk assessment across the pharmaceutical R&D spectrum, from early clinical development to late-stage development to regulatory review to post-launch assessment. The book first presents interpretations of benefit and risk in the context of a molecule moving from preclinical evaluation into its early testing in humans. It next consid...
Parasitism: The Good, The Bad and The Ugly
Parasitism is a tight association between species in which one organism, the parasite, lives on or inside the host, causing it harm, and is structurally adapted to this way of life. Until the twenty-first century, parasitism was studied by parasitologists, rather than ecologists or evolutionary biologists. Today, parasitism is a major element of evolutionary ecology, as nearly all free-living animals are hosts to at least one parasite species. Since it is in the parasite's evolutionary interest for its host to flourish, long-term coevolution can lead to a stable relationship bordering on mutualism. According to Lynn Margulis, when resources are scarce, natural selection, moves relationships from parasitism to mutualism, as it was brilliantly illustrated in Margulis' endosymbiosis theory, where eukaryotic mitochondria and chloroplasts descended from formerly free-living prokaryotes. Boundary between mutualism, symbiosis, and pathological parasitism is a thin red line that frequently overlapping without a theory enough clear to explain this thigh relationship between the parasite and its host.
