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From first principles to real-world applications-here is the first comprehensive guide to drug discovery and development Modern drug discovery and development require the collaborative efforts of specialists in a broadarray of scientific, technical, and business disciplines-from biochemistry to molecular biology, organic chemistry to medicinal chemistry, pharmacology to marketing. Yet surprisingly, until now, there were no authoritative references offering a complete, fully integrated picture of the process. The only comprehensive guide of its kind, this groundbreaking two-volume resource provides an overview of the entire sequence of operations involved in drug discovery and develop-?ment-f...
Biodiversity is declining at an alarming rate due to anthropogenic activities around the world. This book is the second volume in the new series Biodiversity Hotspots of the World, which highlights the 36 hotspot regions of the world, regions that have been designated as reaping maximum benefit from preservation efforts. This series is our humble attempt to document these hotspots as a conservation and preservation measure. The concise volumes in this series focus on the most interesting and important properties of these hotspots, covering physiography and climatology; vegetation and forest types; amphibian and reptile biodiversity; genetic diversity of crops, plants, fishes, butterflies, in...
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
This book is an easy-to-use reference that provides ready guidance on the diagnosis and treatment of the full range of tumors of the central nervous system in adults and children. The new edition has been completely revised to reflect the continually evolving landscape of neuro-oncology and provide readers with a thorough update that will inform their clinical practice. Since the previous edition, molecular neuropathology has progressed considerably, leading to a new understanding of specific clinical entities with corresponding changes in treatment concepts. Moreover, tumor biology has become better integrated with clinical neuro-oncology in truly translational efforts. These advances receive detailed attention. In addition, the structure of the book has been adapted to align with the revised 2016 version of the WHO Brain Tumor Classification. Once again, the contributors have been carefully selected as leading experts in the field. Oncology of CNS Tumors is already established as a widely used reference, and this new edition will provide optimal value for highly specialized comprehensive neuro-oncology centers as well as practicing clinicians and researchers.
Spectroscopic Data Relative to Diatomic Molecules provides information pertinent to the electronic spectrum and spectroscopic properties of diatomic molecules. This book consists of a collection of tables that mainly deal with electronic spectra located in the infrared, the visible and the ultraviolet. Thermochemical data have been used in this book to make estimates of dissociation energies while results from electron diffraction experiments have been used to determine internuclear distances. This text provides information regarding potential energy curves, ionization potential, correlations with atomic states, electronic configuration, lifetimes, transition probabilities, astrophysical applications, and chemical physics. This book is a valuable resource for spectroscopists.
This book is based on the lectures delivered at the 19th Canberra International Physics Summer School held at the Australian National University in Canberra (Australia) in January 2006.The problem of turbulence and coherent structures is of key importance in many fields of science and engineering. It is an area which is vigorously researched across a diverse range of disciplines such as theoretical physics, oceanography, atmospheric science, magnetically confined plasma, nonlinear optics, etc. Modern studies in turbulence and coherent structures are based on a variety of theoretical concepts, numerical simulation techniques and experimental methods, which cannot be reviewed effectively by a ...
This book is based on the proceedings of the COSNet/CSIRO Workshop on Turbulence and Coherent Structures held at the Australian National University in Canberra in January 2006.It codifies recent developments in our understanding of the dynamics and statistical dynamics of turbulence and coherent structures in fluid mechanics, atmospheric and oceanic dynamics, plasma physics, and dynamical systems theory. It brings together articles by internationally acclaimed researchers from around the world including Dijkstra (Utrecht), Holmes (Princeton), Jimenez (UPM and Stanford), Krommes (Princeton), McComb (Edinburgh), Chong (Melbourne), Dewar (ANU), Watmuff (RMIT) and Frederiksen (CSIRO).The book will prove a useful resource for researchers as well as providing an excellent reference for graduate students working in this frontier area.