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It Won't Be Easy
Tom Rademacher wishes someone had handed him this sort of book along with his teaching degree: a clear-eyed, frank, boots-on-the ground account of what he was getting into. But first he had to write it. And as 2014’s Minnesota Teacher of the Year, Rademacher knows what he’s talking about. Less a how-to manual than a tribute to an impossible and impossibly rewarding profession, It Won’t Be Easy captures the experience of teaching in all its messy glory. The book follows a year of teaching, with each chapter tackling a different aspect of the job. Pulling no punches (and resisting no punch lines), he writes about establishing yourself in a new building; teaching meaningful classes, keepi...
Glycoimmunology 2
The Jenner International Glycoimmunology Meetings have charted the rapid devel opment of glycobiology within the field of inflammation. In less than a decade, the science has grown from basically being involved in carbohydrate analysis to the understanding of how sugars are associated with inflammation and how they have potential as anti inflammatory therapeutics. The 4th Jenner International Glycoimmunology Meeting was re cently held in Loutraki, Greece, and set the scene for what promises to be an exciting future for the speciality. Discussion reflected the rapid advances glycobiology is making and ranged from the basic biochemistry of carbohydrate physiology to therapeutic trials utilizin...
Conformal Field Theory, Automorphic Forms and Related Topics
This book, part of the series Contributions in Mathematical and Computational Sciences, reviews recent developments in the theory of vertex operator algebras (VOAs) and their applications to mathematics and physics. The mathematical theory of VOAs originated from the famous monstrous moonshine conjectures of J.H. Conway and S.P. Norton, which predicted a deep relationship between the characters of the largest simple finite sporadic group, the Monster and the theory of modular forms inspired by the observations of J. MacKay and J. Thompson. The contributions are based on lectures delivered at the 2011 conference on Conformal Field Theory, Automorphic Forms and Related Topics, organized by the editors as part of a special program offered at Heidelberg University that summer under the sponsorship of the Mathematics Center Heidelberg (MATCH).
Probability in Banach Spaces, 9
The papers contained in this volume are an indication of the topics th discussed and the interests of the participants of The 9 International Conference on Probability in Banach Spaces, held at Sandjberg, Denmark, August 16-21, 1993. A glance at the table of contents indicates the broad range of topics covered at this conference. What defines research in this field is not so much the topics considered but the generality of the ques tions that are asked. The goal is to examine the behavior of large classes of stochastic processes and to describe it in terms of a few simple prop erties that the processes share. The reward of research like this is that occasionally one can gain deep insight, ev...
The Alkaloids: Chemistry and Pharmacology
The Alkaloids: Chemistry and Pharmacology
Iminosugars
Iminosugars form undoubtedly the most attractive of carbohydrate mimics reported so far. In these structures, the substitution of the endocyclic oxygen of sugars by a basic nitrogen atom leads to remarkable biological properties and raises many challenges in organic synthesis. Since the discovery of their biological activity as glycosidase inhibitors in the 1970’s, these polyvalent molecules have progressively made their way from the laboratory to the clinic. The impressive series of discoveries in the field over the past ten years indicates clearly that it is “a boom time” for iminosugar chemistry and biology. The scope of their profile as inhibitors has been extended to a number of e...
Cellular Cancer Markers
In Cellular Cancer Markers leading pathologists and physicians review today's most promising cellular cancer markers, an important emerging class of prognostic markers that can be used in the clinical evaluation of cancer patients. The markers reviewed have been chosen because they are biologically relevant to the growth of cells and possess an accurate and reproducible assay for detection. They also are predictors of tumor behavior, are useful in making clinical decisions, and are cost effective. Cellular Cancer Markers provides a status report for markers of tumor cell activation, proliferation, and longevity that makes possible an informed judgment regarding the value of many newly proposed tumor markers. It also offers insight into the latest approaches to diagnosing cancer and an appreciation of how these marker-based tests can clarify the prognosis of cancer.
Carbohydrate Chemistry
A review of coverage relevant to the chemistry of monosaccharides and oligosaccharides in a given year.
Complement Regulatory Proteins
From small beginnings in the early 1970s, the study of complement regulatory proteins has grown in the last decade to the point where it dominates the complement field. This growth has been fueled by the discovery of new regulators, the cloning of old and new regulators, the discovery that many of the regulators are structurally and evolutionarily related to each other and the development of recombinant forms for use in therapy. There are now more proteins known to be involved in controlling the complement system than there are components of the system and the list continues to grow. The time is ripe for a comprehensive review of our current knowledge of these intriguing proteins. This book ...
Glycosphingolipids in the Central Nervous System
Glycosphingolipids in the Central Nervous System: Diversity in Structure, Metabolism, Distribution, and Function comprehensively covers progress made in the discovery, profiling and understanding of the metabolism, function and functional mechanism of GSLs in the CNS –as well as their synthesis, relationships with and therapeutic applications to neurodegenerative disorders, and related CNS diseases. Due to the important roles of GSLs in the CNS and various CNS-related diseases, the interest in these biomolecules is growing. GSLs are the principal glycolipids on the cell surface and an essential constituent of the cell membrane. They are widespread, but especially enriched in the central nervous system (CNS) in vertebrates. The diversity of GSL structures forges the molecular foundation for their broad spectrum of activity. - Presents a systematic review of literature and potential future developments in Glycosphingolipid research - Highlights interdisciplinary interplay between various aspects of the neuronal system and its structural and functional properties - Provides an overview, general trends, cases studies, summaries and future implications
