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This text presents a detailed overview of the principal radiologic and pathologic findings of the most common pulmonary diseases. Its primary radiologic emphasis is on the appearance of the diseases and abnormalities. The goal is to offer the radiologist a greater appreciation of the patterns and distribution of the histopathologic abnormalities as shown on the imaging studies, and the pulmonary pathologist better understanding of the radiologic findings. The text features radiologic-pathologic correlation throughout and a strong emphasis on high-resolution CT, which generally provides the best depiction of anatomic features. Reviewers praised the concise and succinct narrative style of the first edition.
Bringing together pathologists, clinicians and diagnostic radiologists to produce a simplified analysis and a unification of the existing concepts in the diagnosis and treatment of diffuse lung diseases, this volume highlights pathological changes and presents the latest diagnostic modalities. Detailed therapeutic strategies are proposed based on epidemiological findings, radiographic manifestations, and the complex pathophysiological basis of each disorder. The result will appeal not only to the sophisticated practitioner but will also provide material that is sufficiently organised and didactic to be used by the young physician.
This book provides readers with a comprehensive and up-to-date guide to non-invasive mechanical ventilation in palliative medicine, focusing on why and when it may be necessary. Physicians will find a practical guide to this specific context, particularly focused on pulmonary function and physiology in the elderly, and on ventilatory management in surgery and chronic stable conditions. The book provides detailed information on the rationale for invasive and non-invasive ventilation, the different modes of ventilation, indications and contraindications, prognostic factors, and outcomes. It addresses in detail the role of postoperative mechanical ventilation following various forms of surgery,...
This book provides a comprehensive and up-to-date review of current understanding of periostin and its importance for human health and disease. Periostin is a secretory matricellular protein that has been revealed to play key roles in fibrillogenesis and cell migration, including metastasis of cancer cells. The production of periostin is upregulated during fibrotic responses and the mechanisms by which it promotes fibrosis have become a focus of interest owing to the potential clinical benefit to be derived from periostin blockade. In this book, readers will find coverage of all aspects, from the basic properties of periostin and its function as a scaffold for assembly of extracellular proteins through to its roles in bone and tissue regeneration, tumorigenesis, myocardial infarction, inflammatory and immune system disorders, and other diseases. Readers will also find the latest information on functions of periostin related to stemness and the application of periostin as a biomarker. It is hoped that the detailed knowledge of periostin and its pathobiological significance provided in this book will aid in the search for effective treatments for currently incurable diseases.
The study of rare lung disorders enhances our understanding of common pulmonary diseases such as fibrosis and emphysema. Molecular Basis of Lung Disease: Insights from Rare Disorders brings together a panel of distinguished clinicians and molecular scientists who are experts in a range of rare lung diseases and their underlying molecular defects. Each chapter focuses on the pathogenic mechanisms and therapeutic targets suggested by basic research and follows an easy to read format: brief introduction followed by discussion of epidemiology, genetic basis and molecular pathogenesis, animal models, clinical presentation, diagnostic approaches, conventional management and treatment strategies, as well as future therapeutic targets and directions. Disorders ranging from the Marfan and Goodpasture’s syndromes to Sarcoidosis and alpha one titrypsin deficiency are treated in detail. Written for pulmonary clinicians and scientists alike, Molecular Basis of Lung Disease: Insights from Rare Disorders is a comprehensive and invaluable nesource that sheds new light on the molecular mechanisms influencing the clinical presentation and treatment strategies for these debilitating disorders.
This extensively illustrated atlas for radiologists, pulmonologists and pathologists describes the anatomic and pathogenetic bases of various radiologic abnormalities seen in chest disease. Organized according to patterns seen on standard chest radiographs and CT scans (e.g., a solitary pulmonary nodule, multiple cavities, etc.), each pattern is defined and illustrated by a number of cases. Also featured is a succinct background of diseases, including clinical and pathological definition. Compatibility: BlackBerry(R) OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile(TM) Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC
Part of the highly regarded Specialty Imaging series, this fully updated second edition by Drs. Santiago Martínez-Jiménez, Melissa L. Rosado-de-Christenson, and Brett W. Carter, reflects the many recent changes in HRCT diagnostic interpretation. An easy-to-read bulleted format and state of the art imaging examples guide you step-by-step through every aspect of thin-section CT and HRCT in the evaluation of patients with suspected lung disease. This book is an ideal resource for radiologists who need an easily accessible tool to help them understand the indications, strengths, and limitations of HRCT in their practice. - Superb illustrations with comprehensive captions display both typical a...
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