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Genetic Instabilities and Neurological Diseases
Genetic Instabilities and Neurological Diseases covers DNA repeat instability and neurological disorders, covering molecular mechanisms of repeat expansion, pathogenic mechanisms, clinical phenotype, parental gender effects, genotype-phenotype correlation, and diagnostic applications of the molecular data. This updated edition provides updates of these repeat expansion mutations, including the addition of many new chapters, and old chapters rewritten as extensions of the previous edition. This book is an invaluable reference source for neuroscientists, geneticists, neurologists, molecular biologists, genetic counsellors and students. - Contributions by most of the principal research teams in the area, edited by world-renowned leaders - Lays the background for future investigations on related diseases
Current Neurology
The goal of the CURRENT NEUROLOGY series is to address the latest advances in the Neurosciences and their application to Neurologic disease. No field is changing more rapidly than Neurology, and all Neurologists have an increasing responsibility to use this information to help devise meaningful therapeutic strategies for the patients. To help achieve this goal, several areas for in-depth discussions are selected. The rapid advances in the muscular dystrophies is addressed with specific emphasis as to how these genetic breakthroughs will impact the therapy of these disorders in the future. Also discussed is therapeutic Neuro-ophthalmology which has always been of clinical importance for importance for Neurologists. Finally, the problem of pain is extremely important, and the latest understanding of neuropeptides and neuronal re-organization are discussed as the basis for future therapeutic approaches.
Neurology Secrets E-Book
Revised and updated, Neurology Secrets, 5th Edition has the answers you need. A two-color page layout, portable size, and a list of the "Top 100 Secrets" in neurology help you better meet the challenges you face today. You’ll find all the features you rely on from the Secrets Series®—a question-and-answer format, lists, mnemonics, tables, and an informal tone—that make study or reference fast and easy. • Expedites reference and review with a question-and-answer format, bulleted lists, mnemonics, and practical tips from the authors. • Features a two-color page layout, "Key Points" boxes, and lists of useful web sites to enhance your reference power. • Presents a chapter containing "Top 100 Secrets," providing you with a quick and concise overview of essential material for last-minute study or self-assessment. • Fits comfortably in the pocket of your lab coat to allow quick access to essential information when you need it the most. • Presents completely revised chapters, covering all of today's most common neurologic conditions and their treatment to keep you up to date.
A Short-Cut to Understanding Affective Neuroscience
A Short-Cut to Understanding Affective Neuroscience is a remarkable book that will appeal to academics and laymen, theoreticians and clinicians. Readers will appreciate Lucy Biven's thorough research and her straightforward language. She does not avoid complexity and uncertainty when addressing challenging questions in neuroscience. -Donald Campbell: Past President and Distinguished Fellow of the British Psychoanalytical Society This book clarifies and evaluates vast amounts of neuroscientific research, arriving at a clear and concise framework that demonstrates how to ground mental health practice in the results of neuroscience. With a seamless narrative that weaves and explains complex the...
Triple Repeat Diseases of the Nervous Systems
World of Unstable Mutations The book "Triplet Repeat Diseases of the Nervous System" overviews the lat est data on several disorders associated with unstable mutations. This field of re search is progressing extremely fast. The number of polymorphic mutations and diseases caused by these mutations is increasing almost every month. There is a strong interest to molecular bases of triplet repeat disorders. This is explained by growing necessity to develop molecular approaches for cure of these diseases. There fore, the authors of this book describe unstable mutations with the emphasis on molecular pathology. Broad discussion is presented on how polymorphic expan sions cause cell dysfunction. o...
Immunobiology of Proteins and Peptides VI
The articles in this volume represent papers delivered by invited speakers at the 6th International Symposium on the Immunobiology of Proteins and Peptides. In addition, a few of the abstracts submitted by participants were scheduled for minisymposia and some of the authors, whose presentations were judged by the Scientific Council to be of high quality, were invited to submit papers for publication in this volume. This symposium was established in 1976 for the purpose of bringing together, once every two or three years, active investigators in the forefront of contemporary immunology, to present their findings and discuss t heir significance in the light of current concepts and to identify ...
Trials for Cerebellar Ataxias
Despite the critical importance of the cerebellum in brain function, the scientific community still lacks effective treatments for most cerebellar ataxias. This book provides a link between the pathogenesis and therapies of cerebellar ataxias while also providing a comprehensive assessment of the preclinical and clinical trials dedicated to cerebellar ataxias over the past 20 years of progress. This is the first book fully dedicated to the trials and therapies of these disorders. It is a truly authoritative and comprehensive reference, and comes at a time of major advances in genetic tools and neuroimaging assessments. The coverage begins by laying a foundation of the basic science of the cerebellum and ataxias, proceeds to discuss biomarkers and the tools of trials, offers guidelines on conducting trials, and then explores the full range of therapeutics and their trials, including gene therapy and cell transplantation. The authors are top experts on cerebellar research and the contributing authors have all made seminal contributions in the field.
Neurology Secrets: First South Asia Edition - E-book
Part of the bestselling Secrets Series, this updated edition of Neurology Secrets continues to provide an up-to-date, concise overview of the most important topics in neurology today. It serves as a comprehensive introduction for medical students, physician assistants, and nurse practitioners, and is also a handy reference and refresher for residents and practitioners. Lists, tables, and clear illustrations throughout expedite review, while the engaging Secrets Series format makes the text both enjoyable and readable. New lead editors, Drs. Kass and Mizrahi, join this publication from a leading neurology program to lend a fresh perspective and expert knowledge. - Expedites reference and review with a question-and-answer format, bulleted lists, and practical tips from the authors. - Covers the full range of essential topics in understanding the practice of neurology. - Features a two-color page layout and "Key Points" boxes to further enhance your reference power. - Presents "Top 100 Secrets" for an overview of essential material for last-minute study or self-assessment. - Fits comfortably in the pocket of your lab coat to allow quick access to essential information.
Huntington's Disease
Huntingtons disease, or Huntingtons chorea, is a progressive genetic disease marked by death of brain cells coupled with loss of muscular control and coordination, declining mental abilities, and erratic behavior. Currently, this form of dementia has no cure. "Huntingtons Disease" offers introduces this disease, detailing its history and progression, and discusses the search for the gene that causes it and the development of genetic tests for the gene. This title also addresses the ethical questions of testing people for a disease whose symptoms typically develop later in life.
