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Cerebellar Disorders
"This book on cerebellar disorders begins with our current understanding of the anatomy and physiology of the cerebellum, and then dives into the diagnosis and treatment of the many different disorders. As virtually all pathological processes can affect the cerebellum, the book actually covers much of neurology. Dr. Manto has been devoted to the study of the cerebellum in his career. His contributions are numerous in many areas, and his enthusiasm led him to found and edit the journal, The Cerebellum, which has rapidly become quite distinguished with an impact factor approaching 4. When dealing with the different disorders, the book approaches the patient in multiple ways. What is the differential diagnosis by age or by pathologic entity? What is the differential diagnosis for recessive, dominant, or X-linked disorders? What laboratory tests should be done to clarify the situation? What scales can be used to quantify the disorder? And then, what can be done for treatment? There is no reason to take a dim view of treatment when the possibilities are taken as a whole for all the ataxias"--Provided by publisher
Cerebellar Disorders
During the last three decades, many laboratories worldwide have dedicated their research activities to understanding the roles of the cerebellum in motor control, cognitive processes and the biology of mental processes, behavioral symptoms and emotion. These advances have been associated with discoveries of new clinical disorders, in particular in the field of genetic ataxias, and the growing number of diseases presents a source of difficulty for clinicians during daily practice. This practical guide summarizes and evaluates current knowledge in the field of cerebellar disorders. Encompassing details of both common and uncommon cerebellar ataxias, including vascular, immune, neoplastic, infectious, traumatic, toxic and inherited disorders, this book will assist clinicians in the diagnosis and management of the full spectrum of cerebellar ataxias encountered in daily practice. Essential reading for clinicians, including general practitioners, neurologists, pediatricians, radiologists, psychiatrists and neuropsychologists, this will also prove a valuable tool for students, trainees and researchers.
The Linguistic Cerebellum
The Linguistic Cerebellum provides a comprehensive analysis of this unique part of the brain that has the most number of neurons, each operating in distinct networks to perform diverse functions. This book outlines how those distinct networks operate in relation to non-motor language skills. Coverage includes cerebellar anatomy and function in relation to speech perception, speech planning, verbal fluency, grammar processing, and reading and writing, along with a discussion of language disorders. Discusses the neurobiology of cerebellar language functions, encompassing both normal language function and language disorders Includes speech perception, processing, and planning Contains cerebellar function in reading and writing Explores how language networks give insight to function elsewhere in the brain
Trials for Cerebellar Ataxias
Despite the critical importance of the cerebellum in brain function, the scientific community still lacks effective treatments for most cerebellar ataxias. This book provides a link between the pathogenesis and therapies of cerebellar ataxias while also providing a comprehensive assessment of the preclinical and clinical trials dedicated to cerebellar ataxias over the past 20 years of progress. This is the first book fully dedicated to the trials and therapies of these disorders. It is a truly authoritative and comprehensive reference, and comes at a time of major advances in genetic tools and neuroimaging assessments. The coverage begins by laying a foundation of the basic science of the cerebellum and ataxias, proceeds to discuss biomarkers and the tools of trials, offers guidelines on conducting trials, and then explores the full range of therapeutics and their trials, including gene therapy and cell transplantation. The authors are top experts on cerebellar research and the contributing authors have all made seminal contributions in the field.
The Cerebellum: Disorders and Treatment
The Cerebellum: Disorders and Treatment, Volume 155 updates readers on the latest and clinically relevant advances in the study of cerebellar diseases in children and adults. It is organized into sections detailing: (1) Disorders (starting from the fetal cerebellum, to adult cerebellum) encountered during daily practice, and (2) Therapy (including insights into innovative drug and rehabilitative approaches). The book's innovative structure discusses cerebellar disorders in children and adults as a continuum, with its companion volume, The Cerebellum: From Embryology to Diagnostic Investigations detailing embryology, anatomy, function and diagnostic investigations and neuroimaging, including conventional sequences, diffusion tensor imaging, functional MRI, and connectivity studies. Provides an in-depth understanding of the cerebellum and its involvement in a wide variety of diseases Explores long-term outcome data of pediatric cerebellar diseases and potential problems in adult life for patients with pediatric cerebellar diseases Features chapters co-authored by two experts, combining expertise in both pediatric and adult cerebellar diseases
The Cerebellum: From Embryology to Diagnostic Investigations
The Cerebellum: From Embryology to Diagnostic Investigations, Volume 154 is designed to update the reader on the latest and clinically relevant advances in the study of cerebellar diseases in children and adults. It is organized into sections detailing: (1) Embryology, Anatomy and Function, and (2) Diagnostic investigations: Neuroimaging, and includes content on conventional sequences, diffusion tensor imaging, functional MRI, and connectivity studies. Its companion volume, The Cerebellum: Disorders and Treatment, describes disorders (starting from the fetal cerebellum, to adult cerebellum) encountered during daily practice and therapy (including insights into innovative drug and rehabilitative approaches to treat children and adults with cerebellar disorders). Provides an in-depth understanding of the cerebellum and its involvement in a wide variety of diseases Explores the long-term outcome data of pediatric cerebellar diseases and potential problems in adult life for patients with pediatric cerebellar diseases Features chapters co-authored by two experts, combining expertise in both pediatric and adult cerebellar diseases
Essentials of Cerebellum and Cerebellar Disorders
This monograph, now in its 2nd edition with 31 new chapters and significant updates, is the first book of its kind written specifically for graduate students and clinicians. The monograph is based on the 4-volume treatise, Handbook of the Cerebellum and Cerebellar Disorders (Springer, 2013; 2nd edition: 2022), the definitive reference for scientists and neurologists in the field of cerebellar neurobiology and related areas. There have been fundamental advances in the basic science and clinical neurology of the cerebellum and its role in sensorimotor function and cognition. Essentials of the Cerebellum and Cerebellar Disorders makes this large and expanding body of knowledge readily accessibl...
4th European Conference of the International Federation for Medical and Biological Engineering 23 - 27 November 2008, Antwerp, Belgium
The 4th European Congress of the International Federation for Medical and Biological Federation was held in Antwerp, November 2008. The scientific discussion on the conference and in this conference proceedings include the following issues: Signal & Image Processing ICT Clinical Engineering and Applications Biomechanics and Fluid Biomechanics Biomaterials and Tissue Repair Innovations and Nanotechnology Modeling and Simulation Education and Professional
Mechanisms and Emerging Therapies in Tremor Disorders
Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness, and damping are all factors that influence the features of tremor. This completely updated new edition discusses the pathophysiology of tremor, including membrane mechanisms and rodent models, the advances in genetics, and the musculoskeletal models pertinent to body oscillations. The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects. The book covers recent advances in ...
The Cerebellum and Its Disorders
The first comprehensive text on the cerebellum and its disorders for many years.
