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The second edition of this book updates, reviews, and discusses the latest findings on the pathophysiology, diagnosis, and management of cardiovascular disease in the older patient. It explains the physiological changes associated with the normal aging process that may lead to the development of disease, to adverse consequences once disease develops, and which alter the risk-benefit equation for medical and other interventions designed to diagnose, assess, and treat cardiovascular disease. Chapters address key issues in the management of cardiovascular disease in the elderly including prevention, coronary artery disease, valvular disease, hypertensive disease, arrhythmias, and interventions. Wherever possible, the authors take an evidence-based approach to recommendations and rely heavily on clinical trials. The value of lifestyle changes in the aging population, the use of primary and secondary prevention strategies, treatments, and complications are also discussed. Cardiovascular Disease in the Elderly offers physicians and other related providers who care for older patients a gold-standard approach to understanding and managing cardiovascular disease in this group.
The thoroughly updated second edition of this key textbook provides an authoritative discussion of cardiovascular disease for the practicing primary care clinician. It examines a variety of disease states with emphasis on risk factors, risk estimation, and established cardiac disease. The book also explores the co-morbid conditions that surround cardiovascular disease. It includes key points, algorithms, case studies, recommendations on evidence-based practice, and summary boxes. A key resource for the busy practitioner, the Second Edition of Comprehensive Cardiovascular Medicine in the Primary Care Setting is designed to give residents, fellows, and primary care physicians the skills to confidently perform assessments, initiate and maintain efficacious therapy, and know when a referral to a cardiologist is advisable.
This book examines new technologies (device and pharmacologic) that have evolved over the past few years in treating peripheral arterial disease. Chapters offer optimal strategies to treat PAD, supported by peer-reviewed data. The pillars of this strategy will focus on (a) changing vessel compliance to allow better lumen expansion, (b) less recoil and dissections, and (c) less bailout stenting. Chapters also review embolic protection devices and apply the adjunctive use of anti-proliferative therapy to maintain good long term outcomes. In addition, the book reviews drug coated balloons and drug eluting stent technologies and other means of drug delivery into the vessel wall. The goal of this...
This issue of PET Clinics focuses on Recent Advances in Imaging with PET, CT, and MR Techniques and is edited by Drs. Habib Zaidi, Abass Alavi and Drew A. Torigian. Articles will include: Total-body PET imaging: Developments in instrumentation; Prospects for total-body PET imaging using plastic scintillators; Total-body imaging: Potential clinical applications; New challenges for PET image reconstruction for total-body imaging; Advances in preclinical PET instrumentation; Applications of hybrid PET/MRI in CNS disorders; Applications of hybrid PET-MRI in MSK disorders; Assessment of total body atherosclerosis burden by PET-CT; Recent advances on CT and MR imaging in radiology; Potential impact of Total Body PET imaging in measuring global disease burden in systemic inflammatory disorders; Applications of PET-MRI in CV disorders; and more!
Comprehensive Cardiovascular Medicine in the Primary Care Setting provides an authoritative, detailed discussion of cardiovascular disease balanced with practical utility. Disease states are explained with emphasis on risk factors, risk estimation, and established cardiac disease. The book also delves into the co-morbid conditions which surround cardiovascular disease, including peripheral vascular disease, chronic kidney disease, depression, and erectile dysfunction, with the goal of improving quality of life for affected individuals. An abundance of algorithms, case studies, and recommendations on evidence-based best practices facilitate rapid learning. A key resource for the busy practitioner, this book is designed to give the reader the skills to confidently perform assessments, initiate and maintain efficacious therapy, and know when a referral to a cardiologist is advisable.
Our life is dominated by hardware: a USB stick, the processor in our laptops or the SIM card in our smart phone. But who or what makes sure that these systems work stably, safely and securely from the word go? The computer - with a little help from humans. The overall name for this is CAD (computer-aided design), and it’s become hard to imagine our modern industrial world without it. So how can we be sure that the hardware and computer systems we use are reliable? By using formal methods: these are techniques and tools to calculate whether a system description is in itself consistent or whether requirements have been developed and implemented correctly. Or to put it another way: they can b...
This Open Access book presents the results of the "Collaborative Embedded Systems" (CrESt) project, aimed at adapting and complementing the methodology underlying modeling techniques developed to cope with the challenges of the dynamic structures of collaborative embedded systems (CESs) based on the SPES development methodology. In order to manage the high complexity of the individual systems and the dynamically formed interaction structures at runtime, advanced and powerful development methods are required that extend the current state of the art in the development of embedded systems and cyber-physical systems. The methodological contributions of the project support the effective and effic...
The topics covered in this book range from modeling and programming languages and environments, via approaches for design and verification, to issues of ethics and regulation. In terms of techniques, there are results on model-based engineering, product lines, mission specification, component-based development, simulation, testing, and proof. Applications range from manufacturing to service robots, to autonomous vehicles, and even robots than evolve in the real world. A final chapter summarizes issues on ethics and regulation based on discussions from a panel of experts. The origin of this book is a two-day event, entitled RoboSoft, that took place in November 2019, in London. Organized with...
Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.
Lipoprotein(a) [Lp(a)] is a unique lipoprotein that has emerged as an independent risk factor for cardiovascular vascular disease. Data from case control, epigenetic and mendelian randomization studies indicate that people with elevated Lp(a) have a two-fold to four-fold increased risk of cardiovascular events compared to people with low Lp(a) levels. Despite this risk, awareness of Lp(a) is still very low among health care providers. Even cardiologists often overlook Lp(a), in part because Lp(a) is not as well-understood as other risk factors and treatment options are still very limited. This book offers an authoritative and comprehensive overview of Lipoprotein(a). It provides an in-depth ...