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Lipoprotein(a) [Lp(a)] is a unique lipoprotein that has emerged as an independent risk factor for cardiovascular vascular disease. Data from case control, epigenetic and mendelian randomization studies indicate that people with elevated Lp(a) have a two-fold to four-fold increased risk of cardiovascular events compared to people with low Lp(a) levels. Despite this risk, awareness of Lp(a) is still very low among health care providers. Even cardiologists often overlook Lp(a), in part because Lp(a) is not as well-understood as other risk factors and treatment options are still very limited. This book offers an authoritative and comprehensive overview of Lipoprotein(a). It provides an in-depth ...
Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. The epidemic of diabetes mellitus is expected to result in one of the steepest rises in human morbidity and mortality ever observed outside of wartime. Insulin resistance is a hallmark of pre-diabetes and type 2 diabetes mellitus, and is characterized by impaired insulin-signaling transduction. Authoritative and comprehensive, Lipoproteins in Diabetes Mellitus details the many changes wrought by insulin resistance and diabetes mellitus on lipid and lipoprotein metabolism. The book begins by summarizing the various techniques to measure lipoproteins and their subclasses. The mechanisms...
This book provides an introduction to the principles of both cardiovascular epidemiology and molecular pathophysiology; as a unique aspect, it also outlines and discusses the molecular concepts underlying epidemiological observations. This second volume is focused on all aspects concerning “secondary risk factors” in terms of diseases associated with enhanced risk for cardiovascular events. The book promotes the use of interdisciplinary approaches in the field of preventive medicine based on recent advances in molecular and cellular pathophysiology. The book offers a valuable resource for researchers in basic biomedical fields and clinical scientists alike, as well as guidelines for novel avenues of research in both basic pathophysiology and cardiovascular therapy and prevention.
Discover the Secrets to a Healthier Heart with "10 Commandments of Heart Health" In "10 Commandments of Heart Health," renowned cardiologists Dr. Warrick Bishop and Dr. Karam Kostner, along with writer Penelope Edman, unveil a groundbreaking approach to understanding and combating one of the world's most prevalent killers: heart disease. This book is not just a guide; it's a lifesaver. Why This Book? Heart disease remains the leading cause of death globally, but Drs. Bishop and Kostner believe it doesn’t have to be this way. Their book offers a blend of expert knowledge, patient experiences, and actionable advice distilled into 10 core principles for heart health. Whether you're looking to...
India in particular and South-Asia in general have witnessed a rapid increase in the prevalence and incidence of cardiovascular disease over the past 25 years. Lifestyles changes, unhealthy diet, lack of regular physical exercise, and obesity have all led to rising prevalence of metabolic syndrome. It is of no wonder that metabolic syndrome is being increasingly recognized as a clinical entity which is believed to be associated with increased risk of cardiovascular disease beyond individual risk factors, though this is at times debated. This monograph addresses the total nuance of metabolic syndrome in its entirety and answers questions frequently asked on this subject. The authors are inter...
This book is an up-to-date and comprehensive reference on lipidology. It will serve as a stimulus to the reader to continue to learn about the ever changing and fascinating field of therapeutic lipidology. It will also empower readers to improve and extend the lives of the patients they so conscientiously serve.
Cardiac Rehabilitation Explained is a must-read for anyone who has recently experienced a cardiac event, such as a heart attack, stenting, or cardiac surgery. This comprehensive guide not only explains the importance of cardiac rehabilitation, but also provides a thorough understanding of the causes of cardiac events, treatments available, and the steps individuals can take to recover or improve their cardiovascular health, thus also making Cardiac Rehabilitation Explained a powerful preventative tool for those who wish, at any age, to be proactive about their health.
Comprising contributions from leading lipidologists from around the world, this book presents the latest and most comprehensive knowledge on the different options for combination therapy of dyslipidemia and includes discussion of future therapies that are currently in late stages of clinical evaluation. Dyslipidemia is a leading cause of cardiovascular morbidity and mortality and most patients with this condition fail to achieve adequate control of their serum lipid levels with monotherapy. However, recent US and European guideline recommendations, based on randomized, controlled trials, fail to discuss combination therapy options for patients with dyslipidemia. Statins remain the mainstay o...
It is very likely that you or someone you love is one of the 30 million people worldwide who has the 'irregularly irregular' heartbeat of atrial fibrillation. Or, it is possible that you may be among the people who do not realise they have this highly unpredictable condition, the impact of which can range from inconvenience to blackout, heart failure or stroke. An ageing population and our Western lifestyle are ensuring that the prevalence of atrial fibrillation, often referred to by its initials, AF, is increasing at such a rate that it is predicted to be the next cardiac epidemic. Despite it being so widespread, AF does not allow a one-treatment-for-all approach. While it can be managed, c...
A number of years ago something incredible, an amazing coincidence, happened that started Doctor Warrick Bishop on the mission to prevent heart attacks rather than try to cure them. He was driving to work one day when he stopped at a commotion by the side of the road. A fun runner had collapsed during a fun run with a heart attack. He helped in his resuscitation only to find out that had seen the very same man two years earlier and reassured him that he was fine. Warrick had missed the chance to make a difference and it nearly cost a life!! . Based on risk calculation and the best practice of the time, he shouldn't have been at high risk.....but he was! This important question started him on...