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Pediatric Vaccines and Vaccinations
This graduate textbook serves as a highly readable guide on vaccines and vaccination in infants, children and adolescents from an European perspective. The first part of the book is dedicated to childhood and adolescent vaccine schedules, maternal and neonatal immunization and safety of vaccines. In a second part we focus on viral and bacterial vaccines. Further chapters discuss pediatric travel vaccines, vaccines in the pipeline and the European registration process. This book is intended to be a reference textbook and will help to standardize the information on vaccines and immunization program in the WHO European Region.
Modern Vaccinology
The recent developments in modern vaccinology are mainly based on: (i) cloning of microbial genes into recombinant vectors containing genetic information for expression of desired neutralizing immunogens; (ii) alternatives of attenuated vectors with deleted genes permitting the insertion of several foreign genes expressing antigens exposed to the host immune system during the abortive replication of such vectors; (iii) combined vaccines with the aim to protect against many diseases with a limited number of administrations; (iv) evidence demonstrating the ability of animals to respond serologically to DNA injections considered as a potential method of vaccination; (v) the possibility to manip...
Feigin and Cherry's Textbook of Pediatric Infectious Diseases - E-Book
Widely considered the premier text in pediatric infectious diseases, Feigin and Cherry's Textbook of Pediatric Infectious Diseases, 9th Edition, provides authoritative, up-to-date coverage of this rapidly changing field. Extensively revised by Drs. James Cherry, Sheldon L. Kaplan, Gail J. Demmler-Harrison, William J. Steinbach, Peter J. Hotez, and new editor John V. Williams, this two-volume reference delivers the information you need on epidemiology, public health, preventive medicine, clinical manifestations, diagnosis, treatment, and much more. It serves as a reliable, everyday resource for practicing ID specialists, and an invaluable reference for medical students, residents, and fellows...
Gastroenteritis Viruses
This important book covers the structure and molecular biology of small round structured viruses (SSRVs) such as caliciviruses and astroviruses, and the basic pathology of infection. It provides readers with the knowledge needed to make progress in the prevention and treatment of these infections. Readers will also find an overview of gastroentitis vaccines, their structure and molecular biology, as well as the basic pathology of infection, epidemiology and surveillance. Provides an interdisciplinary approach, offering contributions from basic and clinical research Discusses the prevention and treatment of regimes Includes an overview of gastroentitis vaccines
Novel Diarrhoea Viruses
Until recently a neglected disease syndrome, diarrhea is responsible for many millions of infant deaths in developing countries. The result of a 1987 symposium, this volume reflects advances in the aetiology of diarrhea while addressing such puzzling problems as the difficulty of growing viruses in a controlled setting. The volume is deliberately restricted to so-called ``novel'' diarrhea viruses and is not concerned with ``classical'' rotaviruses, which have formed the basis of previous symposia. Articles concentrate on: atypical rotaviruses; the enteric adenoviruses; small round viruses such as astroviruses, caliciviruses and Norwalk virus; and the Berne and Breda viruses, suggested as a new family Toroviridae. The contributions come from an interdisciplinary mix of virologists (both human and veterinary), epidemiologists, molecular biologists, and pathologists.
Progress in Vaccinology
Vaccines have historically been considered to be the most cost-effective method for preventing communicable diseases. It was a vaccine that en abled global eradication of the dreaded disease smallpo. .
Guide to Paediatric Drug Development and Clinical Research
Children in the developed world have never enjoyed better medical care: mortality has decreased and many fatal diseases of the past can today be prevented or even cured. However, the current practice of pharmacotherapy in children does not reflect existing scientific knowledge and has come under scrutiny by paediatricians, pharmacists and regulatory authorities. In order to advance the development of medicines tailored to paediatric needs, US and EU legislators have taken action, and the WHO has initiated a global paediatric campaign. This book gives an overview over the worldwide activities that increasingly include children in the development of new medicines. Triggered by both a better un...
Mathematical Studies on Human Disease Dynamics
This volume contains the proceedings of the AMS-SIAM-IMS Joint Summer Research Conference on Modeling the Dynamics of Human Diseases: Emerging Paradigms and Challenges, held in Snowbird, Utah, July 17-21, 2005. The goal of the conference was to bring together leading and upcoming researchers to discuss the latest advances and challenges associated with the modeling of the dynamics of emerging and re-emerging diseases, and to explore various control strategies. The articles included in this book are devoted to some of the significant recent advances, trends, and challenges associated with the mathematical modeling and analysis of the dynamics and control of some diseases of public health impo...
WHO Expert Committee on Biological Standardization
This report presents the recommendations of a WHO Expert Committee commissioned to coordinate activities leading to the adoption of international recommendations to assure the quality safety and efficacy of vaccines blood products and other biological medicines and the establishment of international biological reference standards for these products and related diagnostic devices. The report of particular relevance to manufacturers and national regulatory authorities starts with a discussion of general issues brought to the Committee's attention. The second part of the report contains written specifications that establish international regulatory expectations for the following products; DNA vaccines pertussis (whole cell) vaccine plasma (human) for fractionation rabies vaccine and rotavirus vaccine. The report also provides a risk assessment and defines conditions for the safe production of pandemic strain influenza vaccines. The third part of the report provides information on the status and development of international reference materials for various antibodies antigens blood products and related substances and in vitro diagnostic devices.
