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This book covers every aspect of radiation myelopathy and considers the evidence from all species in which it has been studied. The historical and current understanding of the pathogenesis of this rare but devastating injury is first discussed. The evidence regarding the role of a variety of factors in radiation myelopathy is then reviewed. Readers will find detailed information on the impacts of total radiation dose, radiation volume, dose fractionation, hyper fractionation, age, anatomic level, comorbidities, radiation modifiers, other therapies, and retreatment of the spinal cord. Given the similarity of the pathogenesis of radiation myelopathy in humans and experimental animals, the pote...
Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource. Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of research Combines the knowledge and expertise of over 170 international specialists across 106 chapters Includes new chapters addressing basic science experiments in stem-cell biology, immunology, and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision-making Includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more References for this new edition are online only, accessible via the Wiley Digital Edition code printed inside the front cover or at www.wiley.com/go/forman/hematopoietic.
Fundamentals of Radiation Oncology: Physical, Biological, and Clinical Aspects, Fourth Edition, is written by a team of renowned experts. This book is a must-have resource for anyone practicing radiation oncology. From basic principles to more-advanced planning and delivery of radiation therapy to treat cancer, this book is a go-to resource for mastering the art and science of radiation oncology. - Recent advances in SRS, SBRT, proton therapy, an immunotherapy - New chapters on adaptive radiotherapy, and artificial intelligence in radiation therapy - IMRT and IGRT techniques are covered in depth in all clinical chapters - Latest landmark studies provide evidence-based rationale for recommended treatments - Radiation treatment toxicity and its management
This volume places a strong emphasis on "volume-effects" phenomenon & the radiation pharmacokinetics that is required to achieve timely & accurate predictions of the clinically acceptable radiation responses in the tumor & normal tissues. Such findings are especially appropriate to the current period of self-examination & introspection by the medical profession occasioned by the augmenting concerns of payors & patients alike for the appropriateness & effectiveness of the increasing volume & intensity of medical services now delivered. The proceedings specifically discusses the topics of 3D & IMRT based therapies & their radiobiological & clinical impact.
The aim of this book is to provide a uniquely comprehensive source of information on the entire field of radiation therapy physics. The very significant advances in imaging, computational, and accelerator technologies receive full consideration, as do such topics as the dosimetry of radiolabeled antibodies and dose calculation models. The scope of the book and the expertise of the authors make it essential reading for interested physicians and physicists and for radiation dosimetrists.