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The Welfare of Children
Takes a critical look at the child welfare system, finding that the emphasis on abuse has produced a system that serves largely as a last resort for only the worst and most dramatic cases in child welfare. This book is a blueprint for the comprehensive reform of the child welfare system.
Integrative Bioinformatics
This book provides an overview of the history of integrative bioinformatics and the actual situation and the relevant tools. Subjects cover the essential topics, basic introductions, and latest developments; biological data integration and manipulation; modeling and simulation of networks; as well as a number of applications of integrative bioinformatics. It aims to provide basic introduction of biological information systems and guidance for the computational analysis of systems biology. This book covers a range of issues and methods that unveil a multitude of omics data integration and relevance that integrative bioinformatics has today. It contains a unique compilation of invited and selected articles from the Journal of Integrative Bioinformatics (JIB) and annual meetings of the International Symposium on Integrative Bioinformatics.
Lie Groups and Invariant Theory
This volume, devoted to the 70th birthday of A. L. Onishchik, contains a collection of articles by participants in the Moscow Seminar on Lie Groups and Invariant Theory headed by E. B. Vinberg and A. L. Onishchik. The book is suitable for graduate students and researchers interested in Lie groups and related topics.
Rickettsial Diseases
The only available reference to comprehensively discuss the common and unusual types of rickettsiosis in over twenty years, this book will offer the reader a full review on the bacteriology, transmission, and pathophysiology of these conditions. Written from experts in the field from Europe, USA, Africa, and Asia, specialists analyze specific patho
Anion Channels and Transporters
This book provides an overview on recent progress in anion channels and transporters. It covers multiple scales of analysis ranging from studying the molecular basis of function at atomic resolution to cellular consequences to channel/transporter dysfunction and approaches to correct such processes by pharmacological intervention. Similar anion channels and transporters are expressed in multiple tissues – often fulfilling similar cellular tasks, but also clearly distinct functions. The aim is to combine work on multiple cell and organ systems.
Reviews of Physiology, Biochemistry and Pharmacology 158
Contents E.I. Christensen and R. Nielsen: Role of Megalin and Cubilin in Renal Physiology and Pathophysiology G. Zifarelli and M. Pusch: CLC Chloride Channels and Transporters: A Biophysical and Physiological Perspective S.F.J. van de Graaf, R.J.M. Bindels and J.G.J. Hoenderop: Physiology of Epithelial Ca2 and Mg2+ Transport
Chloride Movements Across Cellular Membranes
All living cells are surrounded by a lipidic membrane that isolates them from the often harsh environment. However, to take up nutrients, to excrete waste, and to communicate among each other, Nature has invented an incredibly diverse set of transmembrane transport proteins. Specialized transporters exist to shuttle electrically charged ions, positive cations like sodium or negative anions like chloride, across the membrane. In the recent years, tremendous progress has been made in the field of chloride transport. The present book presents the state of the art of this rapidly expanding and interest-gaining field of membrane transport. It is addressed at a broad medically, physiologically, biologically, and biophysically interested readership. - Describes the state-of-the-art in anion transport research - Written by leaders in the field - Presents a timely discussion of this rapidly emerging and expanding field
Addictions
Addiction, increasingly perceived as a heterogeneous brain disorder, is one of the most peculiar psychiatric pathologies in that its management involves various, often non-overlapping, resources from the biological, psychological, medical, economical, social, and legal realms. Despite extensive efforts from the players of these various fields, to date there are no reliably effective treatments of addiction. This may stem from a lack of understanding of the etiology and pathophysiology of this disorder as well as from the lack of interest into the potential differences among patients in the way they interact compulsively with their drug. This book offers an overview of the psychobiology of addiction and its current management strategies from pharmacological, social, behavioural, and psychiatric points of view.
The Foster Care Crisis
The inadequacy of the foster care system has long been recognized. One of the biggest obstacles to reforming the system is the relative unavailability of research data from the field, information that would shed light on key empirical trends and pressing issues. ø This long overdue volume provides a much-needed overview of the current state of foster care. Leading researchers and practitioners summarize and discuss the results of their current research, providing through their data an unparalleled, detailed glimpse of the inner workings of the foster care system in its entirety. The volume is also valuable for its survey and syntheses of important issues and trends affecting foster care. Subjects discussed include welfare reform, reporting systems, family reunification, mental health services, and the needs of minority children. Wide-ranging and detailed in its coverage, this collection is destined to become an essential reference and guide to the foster care system.
The Neuroscience of Human Relationships 2e
An exploration of human relationships as understood through basic concepts of interpersonal neurobiology, this revised edition reflects the wealth of social neuroscience research just out, including how mirror neurons, the polyvagal theory, and epigenetics affect the architecture and development of brain systems and, in turn, how we interact with others.
