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The Nucleolus
As the first comprehensive overview of the nucleolus since 1985, The Nucleolus covers our current understanding of the cell nucleolus, including its role in ribosome assembly and its additional newly-discovered activities. The eighteen chapters have been written by experts who are actively engaged in research on the nucleolus and have an in depth review of the following topics: - nucleolar ultrastructure and dynamics, - behavior during mitosis, - ribosomal DNA gene and chromatin structure, - pre-ribosomal RNA transcription, - processing and modification, - ribosome assembly, - small nucleolar RNAs, - proteomics and non-traditional functions of the nucleolus. Separate chapters are also provided for yeast and higher eukaryotes on many topics. The Nucleolus will appeal not only to scientists directly engaged in nucleolar research, but also those working in related areas such as gene expression, protein biosynthesis, ribosome structure, transcription, chromatin structure, molecular genetics and the structure and functions of the cell nucleus in general.
The Functional Nucleus
This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.
Essential Cell Biology: Cell function
Recent advances in our understanding of cells have put cell biology at the centre of biological and medical research. Covers traditional and recently developed techniques and includes the detail necessary for immediate application in the laboratory.
Debating Design
In this book, first published in 2004, William Dembski, Michael Ruse, and other prominent philosophers provide a comprehensive balanced overview of the debate concerning biological origins - a controversial dialectic since Darwin published The Origin of Species in 1859. Invariably, the source of controversy has been 'design'. Is the appearance of design in organisms (as exhibited in their functional complexity) the result of purely natural forces acting without prevision or teleology? Or, does the appearance of design signify genuine prevision and teleology, and, if so, is that design empirically detectable and thus open to scientific inquiry? Four main positions have emerged in response to these questions: Darwinism, self-organisation, theistic evolution, and intelligent design. The contributors to this volume define their respective positions in an accessible style, inviting readers to draw their own conclusions. Two introductory essays furnish a historical overview of the debate.
Cells
Using a collection of articles, gives a brief overview of cell biology, explaining what a cell is, what a virus is, and the differences between prokaryotic and eukaryotic cells and helpful and harmful bacteria.
Who's Who in Fluorescence 2007
The Journal of Fluorescence’s fifth Who’s Who directory publishes the names, contact details, specialty keywords, and a brief description of scientists employing fluorescence methodology and instrumentation in their working lives. In addition, it provides company contact details with a brief list of fluorescence-related products.
RNA Trafficking and Nuclear Structure Dynamics
This volume explores nuclear structure and trafficking involving or relevant to RNA and RNPs. Topics include advances and current problems in the structural organization of different subnuclear compartments, Cajal bodies and gems, speckles containing splicing factors, and PML bodies characteristic of ProMyelocytic leukemia. The book also describes the dynamic aspects of RNA trafficking and the latest technologies for live cell imaging of mRNA.
Principles of Molecular Biology
Includes access to the Student Companion Website with every print copy of the text.Written for the more concise course, Principles of Molecular Biology is modeled after Burton Tropp's successful Molecular Biology: Genes to Proteins and is appropriate for the sophomore level course. The author begins with an introduction to molecular biology, discussing what it is and how it relates to applications in "real life" with examples pulled from medicine and industry. An overview of protein structure and function follows, and from there the text covers the various roles of technology in elucidating the central concepts of molecular biology, from both a historical and contemporary perspective. Tropp ...
Mutation, Randomness, and Evolution
The author draws on a detailed knowledge of mutational mechanisms to argue that the randomness doctrine is best understood, not as a fact-based conclusion, but as the premise of a neo-Darwinian research program focused on selection.
