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Isaac Hecker and His Friends
Story of the founding of the Paulist Fathers.
Systems Biological Approaches in Infectious Diseases
This book brings together the various fields of functional genomics and systems biology that provide information on metabolic function. There is special emphasis on the identification of drug targets. The book includes practical examples from the various "omic" sciences as well as theoretical examples of how integrated knowledge of these sciences can be applied to drug discovery. It is of interest to researchers in the pharmaceutical drug discovery environment.
Advances in Microbial Physiology
Advances in Microbial Physiology is one of the most successful and prestigious series from Academic Press, an imprint of Elsevier. It publishes topical and important reviews, interpreting physiology to include all material that contributes to our understanding of how microorganisms and their component parts work. First published in 1967, it is now in its 55th volume. The Editors have always striven to interpret microbial physiology in the broadest context and have never restricted the contents to "traditional views of whole cell physiology. Now edited by Professor Robert Poole, University of Sheffield, Advances in Microbial Physiology continues to be an influential and very well reviewed series. - 2007 impact factor of 4.9, placing it 13th in the highly competitive category of microbiology - Contributions by leading international scientists - The latest research in microbial physiology
Mass Spectrometry for Microbial Proteomics
New advances in proteomics, driven largely by developments in mass spectrometry, continue to reveal the complexity and diversity of pathogenic mechanisms among microbes that underpin infectious diseases. Therefore a new era in medical microbiology is demanding a rapid transition from current procedures to high throughput analytical systems for the diagnosis of microbial pathogens. This book covers the broad microbiological applications of proteomics and mass spectrometry. It is divided into six sections that follow the general progression in which most microbiology laboratories are approaching the subject –Transition, Tools, Preparation, Profiling by Patterns, Target Proteins, and Data Analysis.
Pathogenomics
The first book on this young, highly dynamic, and expanding field. This comprehensive, interdisciplinary text focuses on those pathogenic bacteria that are of high scientific and public health interest, yet which also display great potential for the development of new diagnostic, prophylactic and therapeutic procedures. The authors cover all aspects of pathogenomics, including methods, genomics and applications. In addition, the ongoing development of genome, transcriptome, proteome and bioinformatic analyses of pathogenic microorganisms and their host interactions makes for a comprehensive introduction to the field of modern genomic analysis. This result is invaluable to researchers and students wishing to gain a general overview of microbial functional genome analysis and pathogenesis, while also representing a good starting point for those new to the area.
Case in Semitic
This book reconstructs the Semitic case system, based on a detailed analysis of the expression of grammatical roles and relations in the attested Semitic languages. It brings typological methods to bear on the study of comparative Semitics and includes detailed analyses of a wide range of data. The book will interest Semiticists and typologists.
Regulated Proteolysis in Microorganisms
This book contains an extensive collection of critical reviews, from leading researchers in the field of regulated protein degradation. It covers the role of regulated proteolysis in a range of microorganisms (from Gram positive, Gram negative and pathogenic bacteria to Archaea and the Baker’s yeast Saccharomyces cerevisiae).
Function and Control of the Spx-Family of Proteins Within the Bacterial Stress Response
This SpringerBrief on Spx reviews the investigations that led to the discovery of Spx and its orthologs and ties together the results of various studies that have explored the function and control of spx in Gram-positive organisms. Spx of Bacillus subtilis has been extensively studied, but very little has been published about it. This book incorporates a number of studies that have been conducted in other Gram positive bacteria, which examined the role of Spx orthologs in stress response, bacterial development and virulence. The book contains an overview that will introduce the protein and its orthologous forms, its association with RNA polymerase, the species of Gram-positive bacteria in which it is found, and the conditions in which it is abundant and active. Spx is a member of a large group of proteins belonging to the ArsC/Spx protein family, so the review touches upon the bioinformatic support for the protein family composition and its meaning with regard to protein structure/function.
Friedrich Hecker
Friedrich Hecker (1811-1881) lived the first half of his life in the Grand Duchy of Baden, a small state in southern Germany. He was a major leader of a rebellion on behalf of the German republican movement in 1848, but his defeat forced him into exile in America. There he spent the second half of his life as a farmer in southern Illinois, helping to found the Republican Party and campaigning among his countrymen in local and national elections. During the Civil War he served bravely, fighting in some of the most important battles. Although much better known in Germany than in America, he founded a remarkable family in the Midwest that is still flourishing and is a major example of the melding of the European and American traditions of liberty. The work draws heavily from original sources, including letters and diaries at the Western Historical Manuscript Collection, the Missouri Historical Society, and the St. Louis Mercantile Library.
