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Climate change continues to impact our health and safety, the economy, and natural systems. With climate-related protections and programs under attack at the federal level, it is critical for cities to address climate impacts locally. Every day there are new examples of cities approaching the challenge of climate change in creative and innovative ways—from rethinking transportation, to greening city buildings, to protecting against sea-level rise. Climate Action Planning is designed to help planners, municipal staff and officials, citizens and others working at local levels to develop and implement plans to mitigate a community's greenhouse gas emissions and increase the resilience of comm...
Providing current information and guidance on the uses of various nucleic acid amplification technologies for clinical laboratory diagnosis, this book goes beyond the Polymerase Chain Reaction to explore a broader range of important alternative DNA/RNA amplification methods including the Ligase Chain Reaction, Q[beta] Replicase Assays and TMA. There are many examples of specific applications of these technologies, discussions of yet unresolved issues and demonstrations of the relevance of these technologies to medical research and disease diagnostics. Individual chapters cover uses of these methods in clinical situations such as detection of food pathogens, viral infections, STDs, Mycobacteria drug resistance mutations, and heritable diseases. Automation, diagnostic test evaluation, and the synthesis of artificial DNA are also discussed. This book is designed for all biomedical scientists interested in the application of molecular biology to clinical diagnosis.
Reviews the latest research in the field for researchers and clinicians. After a general introduction to DNA base excision repair, chapters cover uracil DNA glycosylases, repair of oxidized purines in DNA, mammalian mismatch-specific DNA glycosylases, repair of apurinic/apyrimidic sites in DNA by AP endonucleases, mutagenesis of abasic sites, a pro
Reforming the North offers a broad perspective on the Protestant Reformation in Scandinavia and on the implications of the reformation for Northern history.
The papers in this volume were presented at the 9th Annual International C- puting and Combinatorics Conference (COCOON 2003), held July 25–28, 2003, in Big Sky, MT, USA. The topics cover most aspects of theoretical computer science and combinatorics related to computing. Submissionstotheconferencethisyearwereconductedelectronically.Atotal of 114 papers were submitted, of which 52 were accepted. The papers were evaluated by an international program committee consisting of Nina Amenta, Tetsuo Asano, Bernard Chazelle, Zhixiang Chen, Francis Chin, Kyung-Yong Chwa, Robert Cimikowski, Anne Condon, Michael Fellows, Anna Gal, Michael Hallett,DanielHuson,NaokiKatoh,D.T.Lee,BernardMoret,BrendanMume...
This book constitutes the refereed proceedings of the 10th International Conference on Distributed Computing and Networking, ICDCN 2009, held in Hyderabad, India, during January 3-6, 2009. The 20 papers and 32 short presentations presented together with 3 keynote talks and a memorial lecture on A.K. Choudhury were carefully reviewed and selected from 179 submissions. The topics addressed are sensor networks, multi-core and shared memory, peer-to-peer-computing, reliability and security, distributed computing, network algorithms, fault tolerance and models, fault tolerance and replication, wireless networks, and grid and cluster computing.
In recent years the field of DNA repair has flourished due to new findings on DNA repair mechanisms and the molecular basis of cancer. This volume covers the most recent developments in this research field and contains contributions from scientists working in various fields.
Middleware is a critical foundation needed to leverage the development of a wide range of mobile and ubiquitous applications. Intrinsic challenges when building such middleware require the combination of expertise from areas like distributed systems, networking, software engineering, and application development. This textbook provides a comprehensive introduction to the main fundamental problems, technologies, paradigms, and solutions of concern to developers of middleware for mobile environments. The contributions are grouped into four parts, on networking and programming issues, communication models, middleware issues, and application issues. Each chapter is structured as a self-contained tutorial, presenting an overview of a specific topic and the state-of-the-art solutions for the related problems. In addition, the book also includes an authoritative reference list. The material has been successfully used in several thematic training schools organized by the ESF MiNEMA (Middleware for Network Eccentric and Mobile Applications) program, and the book's organization and presentation is ideal for an advanced course on middleware.
Computing increasingly happens somewhere, with that geographic location important to the computational process itself. Many new and evolving spatial technologies, such as geosensor networks and smartphones, embody this trend. Conventional approaches to spatial computing are centralized, and do not account for the inherently decentralized nature of "computing somewhere": the limited, local knowledge of individual system components, and the interaction between those components at different locations. On the other hand, despite being an established topic in distributed systems, decentralized computing is not concerned with geographical constraints to the generation and movement of information. ...