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Advances in DNA Damage and Repair
In recent years the field of DNA repair has flourished due to new findings on DNA repair mechanisms and the molecular basis of cancer. This volume covers the most recent developments in this research field and contains contributions from scientists working in various fields.
Critical Reviews of Oxidative Stress and Aging
This two-volume reference examines the translational research field of oxidative stress and ageing. It focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases, with the goal of developing new methods for treating the human ageing processes.
Free Radicals in Biology and Medicine
Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and t...
Proceedings of 4th World Congress on Mass Spectrometry 2017
June 19-21, 2017 London, UK Key Topics : Applications of Mass Spectrometry, New Approaches in Mass Spectrometry, Recent Advances and Development in Mass Spectrometry, Mass spectrometry Imaging, Fundamentals of Mass Spectrometry, Ionization Techniques, Mass Spectrometry Configurations and Separation Techniques, Chromatography and High Performance Liquid Chromatography (HPLC), Maintenance, Troubleshooting, Data Analysis and Experimentation in Mass Spectrometry, Mass Spectrometry in Proteome Research, Proteomics and its applications, Mass Spectrometry in Metabolomics and Lipidomics, Hyphenated Techniques (LC-NMR-MS, HPLC-ESI-MS, MC-ICP-MS, HPLC-ICP-MS, UPLC-Q-TOF/MS), Mass spectrometry in environmental analysis, Spectroscopy, Clinical application of mass spectrometry, UV, IR and Ion Spectroscopy, Nuclear Magnetic Resonance(NMR) Spectroscopy, Mass Spectrometry in Toxicology, Mass spectrometry in Analytical Science, Mass Spectrometry in Pharmaceutical Analysis,
Oxidative Damage & Repair
This book was inspired by the presentations delivered at the Oxidative Damage & Repair Symposium (November, 1990). The book is organized into 20 chapters which mirror the 20 session topics of the Oxidative Damage & Repair Symposium.
Thyroid Care: A Nine-Step Program for Busy Women
The prevalence of abnormal thyroid function (hypothyroidism) in the United States is at an increase, despite inadequate screening methods, which leave the true numbers in question. Amongst those that are diagnosed and treated for hypothyroidism there remains a significant population that does not respond to conventional treatment. There are also those who are undiagnosed and are considered subclinical and remain untreated, many progress to hypothyroidism. These two groups may suffer from secondary hypothyroidism (not stemming from an organic disturbance in the pituitary or thyroid gland), the natural history of which may be unknown. Currently there is a lack of a comprehensive, clinically ho...
Tissue Engineering, Stem Cells, and Gene Therapies
Recent years have seen an upsurge of significant interest in cell-based technologies. A range of productive and lively debate have taken place relating to tissue engineering, namely the construction of tissues and whole organs using molecularly-designed resorbable biomaterials to create tissue de novo, the potential use of human embryonic stem cells for transplantation and regenerative medicine, with similar potential for adult-derived stem cells, and gene therapy, in relation to cell transplantation. New findings in biomimetic materials, cell signalling pathways, extracellular matrix receptors and ligands, growth factors, and the human genome project, all present particularly motivating sou...
Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes
Proceedings of a NATO ASI held in Antalya, Turkey, August 31 - September 11, 1997
Path to Effective Recovering of DNA from Formalin-Fixed Biological Samples in Natural History Collections
Museums catalogue our knowledge of the Earth's biodiversity, and their collections represent many decades of work by experts. Access to DNA sequence information in archival specimens would greatly extend knowledge of the genetic relationships within our biosphere. However, molecular genetic analysis of museum specimens has been slowed by the usual practice of fixation and storage of samples in formalin. Formalin is an environmental toxin and induces genetic and chromosomal alterations to the samples. Few of the many attempts to obtain and sequence DNA from formalin-fixed specimens stored in aqueous formalin or ethanol have been successful. All of the protocols are slow, difficult, and often expensive, and few produce DNA fragments longer than 500 base pairs. Path to Effective Recovering of DNA from Formalin-Fixed Biological Samples in Natural History Collections examines past attempts on DNA recovery from formalin-preserved biological specimens and discusses the research needed to advance the development of similar but more efficient and cost-effective protocols.
Sample Preparation for Hyphenated Analytical Techniques
Linking “standard” but often mutually incompatible analytical techniques – so called hyphenation – generally leads to enhanced analytical performance, so hyphenated techniques are widely used in areas where samples are presented in complex matrices, eg environmental, pharmaceutical and biochemical analysis. With these hyphenated techniques, sample preparation is often the most time-consuming step in analysis, particularly where compounds are present in low concentration, and it has a huge influence on the quality of the analytical results. Sample preparation is still not given the importance it deserves, however. The purpose of this book is to demonstrate the sample preparation chemi...
