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Latent Inhibition
Latent inhibition is a phenomenon by which exposure to an irrelevant stimulus impedes the acquisition or expression of conditioned associations with that stimulus. Latent inhibition, an integral part of the learning process, is observed in many species. This comprehensive collection of studies of latent inhibition, from a variety of disciplines including behavioural/cognitive psychology, neuroscience and genetics, focuses on abnormal latent inhibition effects in schizophrenic patients and schizotypal normals. Amongst other things, the book addresses questions such as, is latent inhibition an acquisition or performance deficit? What is the relationship of latent inhibition to habituation, extinction, and learned irrelevance? Does reduced latent inhibition predict creativity? What are the neural substrates, pharmacology, and genetics of latent inhibition? What do latent inhibition research and theories tell us about schizophrenia? This book provides a single point of reference for neuroscience researchers, graduate students, and professionals, such as psychologists and psychiatrists.
Integrative Neuroscience and Personalized Medicine
This book takes an in depth and hard look at the current status and future direction of treatment predictive markers in Personalized Medicine for the brain from the perspectives of the researchers on the cutting edge and those involved in healthcare implementation. The contents provide a comprehensive text suitable as both a pithy introduction to and a clear summary of the "science to solutions" continuum in this developing field of Personalized Medicine and Integrative Neuroscience. The science includes both measures of genes using whole genome approaches and SNIPS as well as BRAINmarkers of direct brain function such as brain imaging, biophysical changes and objective cognitive and behavio...
Eye movement-related brain activity during perceptual and cognitive processing
The recording and analysis of electrical brain activity associated with eye movements has a history of several decades. While the early attempts were primarily focused on uncovering the brain mechanisms of eye movements, more recent approaches use eye movements as markers of the ongoing brain activity to investigate perceptual and cognitive processes. This recent approach of segmenting brain activity based on eye movement behavior has several important advantages. First, the eye movement system is closely related to cognitive functions such as perception, attention and memory. This is not surprising since eye movements provide the easiest and the most accurate way to extract information from...
Trends in Schizophrenia Research
Schizophrenia is a chronic, severe, and disabling psychosis, which is an impairment of thinking in which the interpretation of reality is abnormal. Psychosis is a symptom of a disordered brain. Approximately 1 percent of the population worldwide develops schizophrenia during their lifetime. Although schizophrenia affects men and women with equal frequency, the disorder often appears earlier in men, usually in the late teens or early twenties, than in women, who are generally affected in the twenties to early thirties. People with schizophrenia often suffer symptoms such as hearing internal voices not heard by others, or believing that other people are reading their minds, controlling their t...
Cognition across the psychiatric disorder spectrum: From mental health to clinical diagnosis
Psychiatric symptoms are considered to be distributed along a continuum, from good mental health to a diagnosable psychiatric disorder. In the case of psychosis, subclinical psychotic experiences, which can include odd behaviors, strange speech, unusual perceptual experiences and social/emotional withdrawal, are often referred to as schizotypy. Research examining schizotypal traits in non-clinical populations is rapidly expanding. The exploration of schizotypy allows us to identify areas of overlap with psychiatric disorders (schizophrenia and related disorders) at genetic, biological, environmental and psychosocial levels, thus identifying putative risk factors, as well as exploring potenti...
Schizotypy
For several decades there has been an increasing move towards viewing the psychotic illnesses from a dimensional perspective, seeing them as continuous with healthy functioning. The idea, concentrating mostly on schizophrenia, has generated considerable theoretical debate as well as empirical research, conducted under the rubric of 'schizotypy'. This book offers a timely discussion of the most significant themes and developments in this research area. Divided into four key sections which represent current concerns in schizotypy research – Measurement, Brain and Biology; Development and Environment; Consequences and Outcomes; and Future Directions – chapters reflect a broad range of appro...
Moral Brains
In the last fifteen years, there has been significant interest in studying the brain structures involved in moral judgments using novel techniques from neuroscience. This is the first volume to take stock of fifteen years of research of this fast-growing field of moral neuroscience and recommend future directions for research.
