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#1 NEW YORK TIMES, WALL STREET JOURNAL, AND BOSTON GLOBE BESTSELLER • One of the most acclaimed books of our time: an unforgettable memoir about a young woman who, kept out of school, leaves her survivalist family and goes on to earn a PhD from Cambridge University “Extraordinary . . . an act of courage and self-invention.”—The New York Times NAMED ONE OF THE TEN BEST BOOKS OF THE YEAR BY THE NEW YORK TIMES BOOK REVIEW • ONE OF PRESIDENT BARACK OBAMA’S FAVORITE BOOKS OF THE YEAR • BILL GATES’S HOLIDAY READING LIST • FINALIST: National Book Critics Circle’s Award In Autobiography and John Leonard Prize For Best First Book • PEN/Jean Stein Book Award • Los Angeles Times...
This book presents recent developments in multivariate and robust statistical methods. Featuring contributions by leading experts in the field it covers various topics, including multivariate and high-dimensional methods, time series, graphical models, robust estimation, supervised learning and normal extremes. It will appeal to statistics and data science researchers, PhD students and practitioners who are interested in modern multivariate and robust statistics. The book is dedicated to David E. Tyler on the occasion of his pending retirement and also includes a review contribution on the popular Tyler’s shape matrix.
The Alkaloids: Chemistry and Physiology, Volume VIII: The Indole Alkaloids focuses on the advances in the chemistry of indole alkaloids. This book discusses the tryptamine and its derivatives, postulated biosyntheses of the physostigmine ring system, and source of the alkaloids. The simple lysergic acid amides, mass spectra of mitraphylline and rhynchophylline, and alkaloids of gelsemium species are also elaborated. This text likewise covers the determination of the structure of the alkaloids, stereochemistry of cinchonamine, dimeric alkaloids of calabash curare, and chemistry of the reserpine group. Other topics include the biology of ergot and short history of its active principles up to the discovery of ergotamine. This volume is recommended for chemists and researchers interested in indole alkaloids.
Does Echinacea fight the common cold? Does St. John's Wort (SJW) really counteract depression? What about chondroitin for joint health? Today's healthcare professionals are increasingly confronted with questions from patients who want to use herbal supplements to treat various conditions. A critical and scientific assessment of medicinal plant rese
From Tyler Henry, celebrated medium, comes the ultimate self-help guide detailing the insights the departed have communicated about how to live our best, most meaningful lives. Do you want to live more meaningfully, and in turn fulfill your life’s potential? Do you want to have the capability to transform your life and make it infinitely better, by paying attention to what those who have lived and died have come to understand about the meaning of life itself? As one of the world’s most accomplished mediums, Tyler Henry has had thousands of communications with those who’ve already gone through humanity’s final frontier: physical death. The life lessons he’s learned from those conversations have been truly transformative. In Here & Hereafter Tyler explains that by listening and learning from the departed, following their guidance, and paying attention to what they might have done differently, we can get more fulfillment and purpose from our own lives. Here & Hereafter will shed light on the most powerful understandings Tyler has gained from modern day mediumship—and explain how those understandings can lead us to live a more meaningful life.
Advances in Applied Microbiology
SHORTLISTED FOR THE WILBUR SMITH ADVENTURE WRITING PRIZE 2018 'A great, gripping story, ferociously well-written, with characters that live and breathe' STEF PENNEY, bestselling author of Under a Pole Star
Iminosugars form undoubtedly the most attractive of carbohydrate mimics reported so far. In these structures, the substitution of the endocyclic oxygen of sugars by a basic nitrogen atom leads to remarkable biological properties and raises many challenges in organic synthesis. Since the discovery of their biological activity as glycosidase inhibitors in the 1970’s, these polyvalent molecules have progressively made their way from the laboratory to the clinic. The impressive series of discoveries in the field over the past ten years indicates clearly that it is “a boom time” for iminosugar chemistry and biology. The scope of their profile as inhibitors has been extended to a number of e...
From a bestselling author and economist, a contemporary moral case for economic growth—and a dose of inspiration and optimism about our future possibilities. Growth is good. Through history, economic growth, in particular, has alleviated human misery, improved human happiness and opportunity, and lengthened human lives. Wealthier societies are more stable, offer better living standards, produce better medicines, and ensure greater autonomy, greater fulfillment, and more sources of fun. If we want to continue on our trends of growth, and the overwhelmingly positive outcomes for societies that come with it, every individual must become more concerned with the welfare of those around us. So, ...